메뉴 건너뛰기




Volumn 52, Issue 4, 2006, Pages 253-256

CYP2D6 genotype and phenotype relationship in South Indians

Author keywords

CYP2D6; Genotype phenotype correlation; South Indians

Indexed keywords

CYTOCHROME P450 2D6; DEXTROMETHORPHAN; DEXTRORPHAN; DRUG METABOLITE;

EID: 33845258952     PISSN: 00223859     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (12)

References (18)
  • 1
    • 13544249943 scopus 로고    scopus 로고
    • Genetic polymorphism of Cytochrome P450 2D6 (CYP2D6): Clinical consequences, evolutionary aspects and functional diversity
    • Ingelman-Sundberg M. Genetic polymorphism of Cytochrome P450 2D6 (CYP2D6): Clinical consequences, evolutionary aspects and functional diversity. Pharmacogenomics J 2005;5:6-13.
    • (2005) Pharmacogenomics J , vol.5 , pp. 6-13
    • Ingelman-Sundberg, M.1
  • 5
    • 33845261883 scopus 로고    scopus 로고
    • [Updated Mar 15;Cited 2006 Apr 17]; Available from
    • CYP2D6 allele nomenclature. [Updated 2006 Mar 15;Cited 2006 Apr 17]; Available from: 〈http://www.imm.ki.se/CYPalleles/cyp2d6.htm〉
    • (2006) CYP2D6 Allele Nomenclature
  • 7
    • 0031038038 scopus 로고    scopus 로고
    • Cytochrome P450 2D6 variants in a Caucasian population: Allele frequencies and phenotypic consequences
    • Sachse C, Brockmoller J, Bauer S, Roots I. Cytochrome P450 2D6 variants in a Caucasian population: Allele frequencies and phenotypic consequences. Am J Hum Genet 1997;60:284-95.
    • (1997) Am J Hum Genet , vol.60 , pp. 284-295
    • Sachse, C.1    Brockmoller, J.2    Bauer, S.3    Roots, I.4
  • 9
    • 0025243460 scopus 로고
    • The human CYP2D locus associated with a common genetic defect in drug oxidation: A G1934-A base change in intron 3 of a mutant CYP2D6 allele results in an aberrant 3′ splice recognition site
    • Hanioka N, Kimura S, Meyer UA, Gonzalez FJ. The human CYP2D locus associated with a common genetic defect in drug oxidation: A G1934-A base change in intron 3 of a mutant CYP2D6 allele results in an aberrant 3′ splice recognition site. Am J Hum Genet 1990;47:994-1001.
    • (1990) Am J Hum Genet , vol.47 , pp. 994-1001
    • Hanioka, N.1    Kimura, S.2    Meyer, U.A.3    Gonzalez, F.J.4
  • 10
    • 0029102348 scopus 로고
    • Detection of the poor metabolizer-associated CYP2D6 (D) gene deletion allele by long-PCR technology
    • Steen VM, Andreassen OA, Daly AK, Tefre T, Borresen AL, Idle JR, et al. Detection of the poor metabolizer-associated CYP2D6 (D) gene deletion allele by long-PCR technology. Pharmacogenetics 1995;5:215-23.
    • (1995) Pharmacogenetics , vol.5 , pp. 215-223
    • Steen, V.M.1    Andreassen, O.A.2    Daly, A.K.3    Tefre, T.4    Borresen, A.L.5    Idle, J.R.6
  • 11
    • 0027527966 scopus 로고
    • Evidence for a new variant CYP2D6 allele CYP2D6J in a Japanese population associated with lower in vivo rates of sparteine metabolism
    • Yokota H, Tamura S, Furuya H, Kimura S, Watanabe M, Kanazawa I, et al. Evidence for a new variant CYP2D6 allele CYP2D6J in a Japanese population associated with lower in vivo rates of sparteine metabolism. Pharmacogenetics 1993;3:256-63.
    • (1993) Pharmacogenetics , vol.3 , pp. 256-263
    • Yokota, H.1    Tamura, S.2    Furuya, H.3    Kimura, S.4    Watanabe, M.5    Kanazawa, I.6
  • 12
    • 0026731087 scopus 로고
    • Determination of dextromethorphan and its O-demethylated metabolite from urine
    • Marshal PS, Straka RJ, Johnson K. Determination of dextromethorphan and its O-demethylated metabolite from urine. Ther Drug Monit 1992;14:402-7.
    • (1992) Ther Drug Monit , vol.14 , pp. 402-407
    • Marshal, P.S.1    Straka, R.J.2    Johnson, K.3
  • 13
    • 0032586732 scopus 로고    scopus 로고
    • Analysis of the CYP2D6 gene in relation to dextromethorphan O-demethylation capacity in a Japanese population
    • Tateishi T, Chida M, Ariyoshi N, Mizorogi Y, Kamataki T, Kobayashi S. Analysis of the CYP2D6 gene in relation to dextromethorphan O-demethylation capacity in a Japanese population. Clin Pharmacol Ther 1999;65:570-5.
    • (1999) Clin Pharmacol Ther , vol.65 , pp. 570-575
    • Tateishi, T.1    Chida, M.2    Ariyoshi, N.3    Mizorogi, Y.4    Kamataki, T.5    Kobayashi, S.6
  • 14
    • 0034094251 scopus 로고    scopus 로고
    • Frequencies of CYP2D6 mutant alleles in a normal Japanese population and metabolic activity of dextromethorphan O-demethylation in different CYP2D6 genotypes
    • Kubota T, Yamaura Y, Ohkawa N, Hara H, Chiba K. Frequencies of CYP2D6 mutant alleles in a normal Japanese population and metabolic activity of dextromethorphan O-demethylation in different CYP2D6 genotypes. Br J Clin Pharmacol 2000;50:31-4.
    • (2000) Br J Clin Pharmacol , vol.50 , pp. 31-34
    • Kubota, T.1    Yamaura, Y.2    Ohkawa, N.3    Hara, H.4    Chiba, K.5
  • 15
    • 0034894010 scopus 로고    scopus 로고
    • CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: A first step towards subpopulation-specific dosages
    • Kirchheiner J, Brosen K, Dahl ML, Gram LF, Kasper S, Roots I, et al. CYP2D6 and CYP2C19 genotype-based dose recommendations for antidepressants: A first step towards subpopulation-specific dosages. Acta Psychiatr Scand 2001;104:173-92.
    • (2001) Acta Psychiatr Scand , vol.104 , pp. 173-192
    • Kirchheiner, J.1    Brosen, K.2    Dahl, M.L.3    Gram, L.F.4    Kasper, S.5    Roots, I.6
  • 16
    • 0029853664 scopus 로고    scopus 로고
    • A novel mutant variant of the CYP2D6 gene (CYP2D6*17) common in a black African population: Association with diminished debrisoquine hydroxylase activity
    • Masimirembwa C, Persson I, Bertilsson L, Hasler J, Ingelman-Sundberg M. A novel mutant variant of the CYP2D6 gene (CYP2D6*17) common in a black African population: Association with diminished debrisoquine hydroxylase activity. Br J Clin Pharmacol 1996;42:713-9.
    • (1996) Br J Clin Pharmacol , vol.42 , pp. 713-719
    • Masimirembwa, C.1    Persson, I.2    Bertilsson, L.3    Hasler, J.4    Ingelman-Sundberg, M.5
  • 18
    • 0032922093 scopus 로고    scopus 로고
    • CYP2D6 polymorphism in a Gabonese population: Contribution of the CYP2D6*2 and CYP2D6*17 alleles to the high prevalence of the intermediate metabolic phenotype
    • Panserat S, Sica L, Gerard N, Mathieu H, Jacqz-Aigrain E, Krishnamoorthy R. CYP2D6 polymorphism in a Gabonese population: Contribution of the CYP2D6*2 and CYP2D6*17 alleles to the high prevalence of the intermediate metabolic phenotype. Br J Clin Pharmacol 1999;47:121-4.
    • (1999) Br J Clin Pharmacol , vol.47 , pp. 121-124
    • Panserat, S.1    Sica, L.2    Gerard, N.3    Mathieu, H.4    Jacqz-Aigrain, E.5    Krishnamoorthy, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.