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Volumn 218, Issue 6, 2006, Pages 355-365

Immunotherapy in children: Report from the Reisensburg-Symposium October 20-22, 2004 and recent advances

Author keywords

Children; Clinical application; Immunotherapy; Phase I II studies

Indexed keywords

ANTIINFECTIVE AGENT; ANTILEUKEMIC AGENT; ANTINEOPLASTIC AGENT; CANCER VACCINE; CYCLOPHOSPHAMIDE; DOXORUBICIN; PREDNISONE; RITUXIMAB; TUMOR ANTIGEN; VINCRISTINE;

EID: 33845251109     PISSN: 03008630     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-942277     Document Type: Article
Times cited : (4)

References (61)
  • 1
    • 2942752408 scopus 로고    scopus 로고
    • Characterization of CD34+ progenitor-derived dendritic cells pulsed with tumor cell lysate for a vaccination strategy in children with malignant solid tumors and a poor prognosis
    • Ackermann B, Troger A, Glouchkova L, Korholz D, Gobel U, Dilloo D. Characterization of CD34+ progenitor-derived dendritic cells pulsed with tumor cell lysate for a vaccination strategy in children with malignant solid tumors and a poor prognosis. Klin Padiatr 2004; 216: 176-182
    • (2004) Klin Padiatr , vol.216 , pp. 176-182
    • Ackermann, B.1    Troger, A.2    Glouchkova, L.3    Korholz, D.4    Gobel, U.5    Dilloo, D.6
  • 2
    • 0029841565 scopus 로고    scopus 로고
    • Antigen-specific targeting of CD28-mediated T cell co-stimulation using chimeric single-chain antibody variable fragment-CD28 receptors
    • Alvarez-Vallina L, Hawkins RE. Antigen-specific targeting of CD28-mediated T cell co-stimulation using chimeric single-chain antibody variable fragment-CD28 receptors. Eur J Immunol 1996; 26: 2304-2309
    • (1996) Eur J Immunol , vol.26 , pp. 2304-2309
    • Alvarez-Vallina, L.1    Hawkins, R.E.2
  • 14
    • 0037481021 scopus 로고    scopus 로고
    • Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence
    • Cavalieri S, Cazzaniga S, Geuna M, Magnani Z, Bordignon C, Naldini L, Bonini C. Human T lymphocytes transduced by lentiviral vectors in the absence of TCR activation maintain an intact immune competence. Blood 2003; 102: 497-505
    • (2003) Blood , vol.102 , pp. 497-505
    • Cavalieri, S.1    Cazzaniga, S.2    Geuna, M.3    Magnani, Z.4    Bordignon, C.5    Naldini, L.6    Bonini, C.7
  • 16
    • 0036179943 scopus 로고    scopus 로고
    • Pilot trial of tumor-specific peptide vaccination and continuous infusion interleukin-2 in patients with recurrent Ewing sarcoma and alveolar rhabdomyosarcoma: An inter-institute NIH study
    • Dagher R, Long LM, Read EJ, Leitman SF, Carter CS, Tsokos M, Goletz TJ, Avila N, Berzofsky JA, Helman LJ, Mackall CL. Pilot trial of tumor-specific peptide vaccination and continuous infusion interleukin-2 in patients with recurrent Ewing sarcoma and alveolar rhabdomyosarcoma: an inter-institute NIH study. Med Pediatr Oncol 2002; 38: 158-164
    • (2002) Med Pediatr Oncol , vol.38 , pp. 158-164
    • Dagher, R.1    Long, L.M.2    Read, E.J.3    Leitman, S.F.4    Carter, C.S.5    Tsokos, M.6    Goletz, T.J.7    Avila, N.8    Berzofsky, J.A.9    Helman, L.J.10    Mackall, C.L.11
  • 18
    • 0347994955 scopus 로고    scopus 로고
    • Activation of resting human primary T cells with chimeric receptors: Costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain
    • Finney HM, Akbar AN, Lawson AD. Activation of resting human primary T cells with chimeric receptors: costimulation from CD28, inducible costimulator, CD134, and CD137 in series with signals from the TCR zeta chain. J Immunol 2004; 172:104-113
    • (2004) J Immunol , vol.172 , pp. 104-113
    • Finney, H.M.1    Akbar, A.N.2    Lawson, A.D.3
  • 19
    • 27444442561 scopus 로고    scopus 로고
    • A generic RNA-pulsed dendritic cell vaccine strategy for renal cell carcinoma
    • Geiger C, Regn S, Weinzierl A, Noessner E, Schendel DJ. A generic RNA-pulsed dendritic cell vaccine strategy for renal cell carcinoma. J Transl Med 2005; 3: 29
    • (2005) J Transl Med , vol.3 , pp. 29
    • Geiger, C.1    Regn, S.2    Weinzierl, A.3    Noessner, E.4    Schendel, D.J.5
  • 21
    • 1542358819 scopus 로고    scopus 로고
    • Cytotoxic activity of natural killer cells lacking killer-inhibitory receptors for self-HLA class I molecules against autologous hematopoietic stem cells in healthy individuals
    • Grau R, Lang KS, Wernet D, Lang P, Niethammer D, Pusch CM, Handgretinger R. Cytotoxic activity of natural killer cells lacking killer-inhibitory receptors for self-HLA class I molecules against autologous hematopoietic stem cells in healthy individuals. Exp Mol Pathol 2004; 76: 90-98
    • (2004) Exp Mol Pathol , vol.76 , pp. 90-98
    • Grau, R.1    Lang, K.S.2    Wernet, D.3    Lang, P.4    Niethammer, D.5    Pusch, C.M.6    Handgretinger, R.7
  • 22
    • 7744234339 scopus 로고    scopus 로고
    • Cellular therapy of Epstein-Barr-virus-associated post-transplant lymphoproliferative disease
    • Heslop HE, Savoldo B, Rooney CM. Cellular therapy of Epstein-Barr-virus- associated post-transplant lymphoproliferative disease. Best Pract Res Clin Haematol 2004; 17; 401-413
    • (2004) Best Pract Res Clin Haematol , vol.17 , pp. 401-413
    • Heslop, H.E.1    Savoldo, B.2    Rooney, C.M.3
  • 23
    • 0041308270 scopus 로고    scopus 로고
    • Kinetics of cell death in T lymphocytes genetically modified with two novel suicide fusion genes
    • Junker K, Koehl U, Zimmerman S, Stein S, Schwabe D, Klingebiel T, Grez M. Kinetics of cell death in T lymphocytes genetically modified with two novel suicide fusion genes. Gene Ther 2003; 10: 1189-1197
    • (2003) Gene Ther , vol.10 , pp. 1189-1197
    • Junker, K.1    Koehl, U.2    Zimmerman, S.3    Stein, S.4    Schwabe, D.5    Klingebiel, T.6    Grez, M.7
  • 25
    • 14844356322 scopus 로고    scopus 로고
    • Approval of clinical trials of immunobiological medicinal products at the Paul Ehrlich Institute
    • Krafft H, Cichutek K. [Approval of clinical trials of immunobiological medicinal products at the Paul Ehrlich Institute]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 2005; 48: 168-172
    • (2005) Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz , vol.48 , pp. 168-172
    • Krafft, H.1    Cichutek, K.2
  • 26
    • 2342585342 scopus 로고    scopus 로고
    • Chimeric CD19 antibody mediates cytotoxic activity against leukemic blasts with effector cells from pediatric patients who received T-cell-depleted allografts
    • Lang P, Barbin K, Feuchtinger T, Greil J, Peipp M, Zunino SJ, Pfeiffer M, Handgretinger R, Niethammer D, Fey GH. Chimeric CD19 antibody mediates cytotoxic activity against leukemic blasts with effector cells from pediatric patients who received T-cell-depleted allografts. Blood 2004; 103: 3982-3985
    • (2004) Blood , vol.103 , pp. 3982-3985
    • Lang, P.1    Barbin, K.2    Feuchtinger, T.3    Greil, J.4    Peipp, M.5    Zunino, S.J.6    Pfeiffer, M.7    Handgretinger, R.8    Niethammer, D.9    Fey, G.H.10
  • 28
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells
    • Le Blanc K, Rasmusson I, Sundberg B, Gotherstrom C, Hassan M, Uzunel M, Ringden O. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 2004; 363: 1439-1441
    • (2004) Lancet , vol.363 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3    Gotherstrom, C.4    Hassan, M.5    Uzunel, M.6    Ringden, O.7
  • 31
    • 0033660412 scopus 로고    scopus 로고
    • Tyrosine hydroxylase-based DNA-vaccination is effective against murine neuroblastoma
    • Lode HN, Pertl U, Xiang R, Gaedicke G, Reisfeld RA. Tyrosine hydroxylase-based DNA-vaccination is effective against murine neuroblastoma. Med Pediatr Oncol 2000; 35: 641-646
    • (2000) Med Pediatr Oncol , vol.35 , pp. 641-646
    • Lode, H.N.1    Pertl, U.2    Xiang, R.3    Gaedicke, G.4    Reisfeld, R.A.5
  • 33
    • 0034068948 scopus 로고    scopus 로고
    • Amplification of T cell-mediated immune responses by antibody-cytokine fusion proteins
    • Lode HN, Xiang R, Gillies SD, Reisfeld RA. Amplification of T cell-mediated immune responses by antibody-cytokine fusion proteins. Immunol Invest 2000; 29: 117-120
    • (2000) Immunol Invest , vol.29 , pp. 117-120
    • Lode, H.N.1    Xiang, R.2    Gillies, S.D.3    Reisfeld, R.A.4
  • 35
    • 0142215546 scopus 로고    scopus 로고
    • T-cell alloreactivity dominates natural killer cell alloreactivity in minimally T-cell-depleted HLA-non-identical paediatric bone marrow transplantation
    • Lowe EJ, Turner V, Handgretinger R, Horwitz EM, Benaim E, Hale GA, Woodard P, Leung W. T-cell alloreactivity dominates natural killer cell alloreactivity in minimally T-cell-depleted HLA-non-identical paediatric bone marrow transplantation. Br J Haematol 2003; 123: 323-326
    • (2003) Br J Haematol , vol.123 , pp. 323-326
    • Lowe, E.J.1    Turner, V.2    Handgretinger, R.3    Horwitz, E.M.4    Benaim, E.5    Hale, G.A.6    Woodard, P.7    Leung, W.8
  • 36
    • 0036436213 scopus 로고    scopus 로고
    • Enhancing immune reconstitution after stem cell transplants with cytokines
    • Mackall CL. Enhancing immune reconstitution after stem cell transplants with cytokines. Cytotherapy 2002; 4: 427-428
    • (2002) Cytotherapy , vol.4 , pp. 427-428
    • Mackall, C.L.1
  • 37
    • 2942595706 scopus 로고    scopus 로고
    • Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation
    • Meisel R, Zibert A, Laryea M, Gobel U, Daubener W, Dilloo D. Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation. Blood 2004; 103: 4619-4621
    • (2004) Blood , vol.103 , pp. 4619-4621
    • Meisel, R.1    Zibert, A.2    Laryea, M.3    Gobel, U.4    Daubener, W.5    Dilloo, D.6
  • 38
    • 4444243490 scopus 로고    scopus 로고
    • Killer immunoglobulin-like receptors
    • Moretta L, Moretta A. Killer immunoglobulin-like receptors. Curr Opin Immunol 2004; 16: 626-633
    • (2004) Curr Opin Immunol , vol.16 , pp. 626-633
    • Moretta, L.1    Moretta, A.2
  • 40
    • 13844281761 scopus 로고    scopus 로고
    • T cell suicide gene therapy to aid haematopoietic stem cell transplantation
    • Qasim W, Gaspar HB, Thrasher AJ. T cell suicide gene therapy to aid haematopoietic stem cell transplantation. Curr Gene Ther 2005; 5: 121-132
    • (2005) Curr Gene Ther , vol.5 , pp. 121-132
    • Qasim, W.1    Gaspar, H.B.2    Thrasher, A.J.3
  • 41
    • 21044431642 scopus 로고    scopus 로고
    • Improving the ex vivo retroviral-mediated suicide-gene transfer process in T lymphocytes to preserve immune function
    • Robinet E, Fehse B, Ebeling S, Sauce D, Ferrand C, Tiberghien P. Improving the ex vivo retroviral-mediated suicide-gene transfer process in T lymphocytes to preserve immune function. Cytotherapy 2005; 7: 150-157
    • (2005) Cytotherapy , vol.7 , pp. 150-157
    • Robinet, E.1    Fehse, B.2    Ebeling, S.3    Sauce, D.4    Ferrand, C.5    Tiberghien, P.6
  • 42
    • 3042772669 scopus 로고    scopus 로고
    • Genetic modification of T lymphocytes for adoptive immunotherapy
    • Rossig C, Brenner MK. Genetic modification of T lymphocytes for adoptive immunotherapy. Mol Ther 2004; 10: 5-18
    • (2004) Mol Ther , vol.10 , pp. 5-18
    • Rossig, C.1    Brenner, M.K.2
  • 46
    • 22044450331 scopus 로고    scopus 로고
    • Cytotoxic minor histocompatibility antigen HA-1-specific CD8+ effector memory T cells: Artificial APCs pave the way for clinical application by potent primary in vitro induction
    • Schilbach K, Kerst G, Walter S, Eyrich M, Wernet D, Handgretinger R, Xie W, Rammensee HG, Muller I, Buhring HJ, Niethammer D. Cytotoxic minor histocompatibility antigen HA-1-specific CD8+ effector memory T cells: artificial APCs pave the way for clinical application by potent primary in vitro induction. Blood 2005; 106: 144-149
    • (2005) Blood , vol.106 , pp. 144-149
    • Schilbach, K.1    Kerst, G.2    Walter, S.3    Eyrich, M.4    Wernet, D.5    Handgretinger, R.6    Xie, W.7    Rammensee, H.G.8    Muller, I.9    Buhring, H.J.10    Niethammer, D.11
  • 48
    • 4444371613 scopus 로고    scopus 로고
    • Consolidation treatment with chimeric anti-GD2-antibody ch14.18 in children older than 1 year with metastatic neuroblastoma
    • Simon T, Hero B, Faldum A, Handgretinger R, Schrappe M, Niethammer D, Berthold F. Consolidation treatment with chimeric anti-GD2-antibody ch14.18 in children older than 1 year with metastatic neuroblastoma. J Clin Oncol 2004; 22: 3549-3557
    • (2004) J Clin Oncol , vol.22 , pp. 3549-3557
    • Simon, T.1    Hero, B.2    Faldum, A.3    Handgretinger, R.4    Schrappe, M.5    Niethammer, D.6    Berthold, F.7
  • 49
    • 18944401132 scopus 로고    scopus 로고
    • Infants with stage 4 neuroblastoma: The impact of the chimeric anti-GD2-antibody ch14.18 consolidation therapy
    • Simon T, Hero B, Faldum A, Handgretinger R, Schrappe M, Niethammer D, Berthold F. Infants with stage 4 neuroblastoma: the impact of the chimeric anti-GD2-antibody ch14.18 consolidation therapy. Klin Padiatr 2005; 217: 147-152
    • (2005) Klin Padiatr , vol.217 , pp. 147-152
    • Simon, T.1    Hero, B.2    Faldum, A.3    Handgretinger, R.4    Schrappe, M.5    Niethammer, D.6    Berthold, F.7
  • 51
    • 18144382659 scopus 로고    scopus 로고
    • Immunotherapy in allogeneic hematopoietic stem cell transplantation-not just a case for effector cells
    • Troeger A, Meisel R, Moritz T, Dilloo D. Immunotherapy in allogeneic hematopoietic stem cell transplantation-not just a case for effector cells. Bone Marrow Transplant 2005; 35 (Suppl 1): S 59- S 64
    • (2005) Bone Marrow Transplant , vol.35 , Issue.SUPPL. 1
    • Troeger, A.1    Meisel, R.2    Moritz, T.3    Dilloo, D.4
  • 52
    • 0034885940 scopus 로고    scopus 로고
    • Chimeric antigen receptors for the retargeting of cytotoxic effector cells
    • Uherek C, Groner B, Wels W. Chimeric antigen receptors for the retargeting of cytotoxic effector cells. J Hematother Stem Cell Res 2001; 10: 523-534
    • (2001) J Hematother Stem Cell Res , vol.10 , pp. 523-534
    • Uherek, C.1    Groner, B.2    Wels, W.3
  • 53
    • 0037103311 scopus 로고    scopus 로고
    • Retargeting of natural killer-cell cytolytic activity to ErbB2-expressing cancer cells results in efficient and selective tumor cell destruction
    • Uherek C, Tonn T, Uherek B, Becker S, Schnierle B, Klingemann HG, Wels W. Retargeting of natural killer-cell cytolytic activity to ErbB2-expressing cancer cells results in efficient and selective tumor cell destruction. Blood 2002; 100: 1265-1273
    • (2002) Blood , vol.100 , pp. 1265-1273
    • Uherek, C.1    Tonn, T.2    Uherek, B.3    Becker, S.4    Schnierle, B.5    Klingemann, H.G.6    Wels, W.7
  • 54
    • 0036326792 scopus 로고    scopus 로고
    • Definition of gene content for nine common group B haplotypes of the Caucasoid population: KIR haplotypes contain between seven and eleven KIR genes
    • Uhrberg M, Parham P, Wernet P. Definition of gene content for nine common group B haplotypes of the Caucasoid population: KIR haplotypes contain between seven and eleven KIR genes. Immunogenetics 2002; 54: 221-229
    • (2002) Immunogenetics , vol.54 , pp. 221-229
    • Uhrberg, M.1    Parham, P.2    Wernet, P.3
  • 56
    • 0142215564 scopus 로고    scopus 로고
    • The role of haploidentical stem cell transplantation in the management of children with haematological disorders
    • Veys P, Amrolia P, Rao K. The role of haploidentical stem cell transplantation in the management of children with haematological disorders. Br J Haematol 2003; 123: 193-206
    • (2003) Br J Haematol , vol.123 , pp. 193-206
    • Veys, P.1    Amrolia, P.2    Rao, K.3
  • 57
    • 0242495753 scopus 로고    scopus 로고
    • Cutting edge: Predetermined avidity of human CD8 T cells expanded on calibrated MHC/anti-CD28-coated microspheres
    • Walter S, Herrgen L, Schoor O, Jung G, Wernet D, Buhring HJ, Rammensee HG, Stevanovic S. Cutting edge: predetermined avidity of human CD8 T cells expanded on calibrated MHC/anti-CD28-coated microspheres. J Immunol 2003; 171: 4974-4978
    • (2003) J Immunol , vol.171 , pp. 4974-4978
    • Walter, S.1    Herrgen, L.2    Schoor, O.3    Jung, G.4    Wernet, D.5    Buhring, H.J.6    Rammensee, H.G.7    Stevanovic, S.8
  • 58
    • 1542297653 scopus 로고    scopus 로고
    • Recombinant immunotoxins and retargeted killer cells: Employing engineered antibody fragments for tumor-specific targeting of cytotoxic effectors
    • Wels W, Biburger M, Muller T, Dalken B, Giesubel U, Tonn T, Uherek C. Recombinant immunotoxins and retargeted killer cells: employing engineered antibody fragments for tumor-specific targeting of cytotoxic effectors. Cancer Immunol Immunother 2004; 53: 217-226
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 217-226
    • Wels, W.1    Biburger, M.2    Muller, T.3    Dalken, B.4    Giesubel, U.5    Tonn, T.6    Uherek, C.7
  • 61
    • 12944279749 scopus 로고    scopus 로고
    • A novel four-colour flow cytometric assay to determine natural killer cell or T-cell-mediated cellular cytotoxicity against leukaemic cells in peripheral or bone marrow specimens containing greater than 20% of normal cells
    • Zimmermann SY, Esser R, Rohrbach E, Klingebiel T, Koehl U. A novel four-colour flow cytometric assay to determine natural killer cell or T-cell-mediated cellular cytotoxicity against leukaemic cells in peripheral or bone marrow specimens containing greater than 20% of normal cells. J Immunol Methods 2005; 296: 63-76
    • (2005) J Immunol Methods , vol.296 , pp. 63-76
    • Zimmermann, S.Y.1    Esser, R.2    Rohrbach, E.3    Klingebiel, T.4    Koehl, U.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.