Validation of a method for acute and subchronic exposure of cells in vitro to volatile organic solvents

Toxicology in Vitro

Volumn 21, Issue 1, 2007, Pages 116-124

  McDermott, Catherine ^a   Allshire, Ashley ^a   van Pelt, Frank N A M ^a   Heffron, James J A ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

In vitro; Partition coefficient; Volatile organic solvent

Indexed keywords

2 BUTANONE; HEXANE; TOLUENE; TRYPAN BLUE; VOLATILE ORGANIC COMPOUND;

ARTICLE; CALCULATION; CELL CULTURE; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CULTURE MEDIUM; EXPOSURE; GAS; GAS CHROMATOGRAPHY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LIPOPHILICITY; PARTITION COEFFICIENT; RELIABILITY; STATISTICAL SIGNIFICANCE; VALIDATION STUDY;

ACUTE DISEASE; ACUTE TOXICITY TESTS; ALGORITHMS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, GAS; CHRONIC DISEASE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; JURKAT CELLS; NEUROBLASTOMA; SOLVENTS; TOLUENE; TOXICITY TESTS, CHRONIC; TRYPAN BLUE;

EID: 33845226133     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2006.08.002     Document Type: Article

References (37)

1. Al-Ghamdi S.S., Raftery M.J., and Yaqoob M.M. Acute solvent exposure induced activation of cytochrome P450E1 causes proximal tubular necrosis by oxidative stress. Toxicology in Vitro 17 (2003) 335-341
2. Anderson D., and Russell T. The Status of Alternative Methods in Toxicology (1995), The Royal Society of Chemistry
3. Bakand S., Winder C., Khalil C., and Hayes A. A novel in vitro exposure technique for toxicity testing of selected volatile organic compounds. Journal of Environmental Monitoring 8 (2006) 100-105
4. Blaauboer B.J. The applicability of in vitro-derived data in hazard identification and characterisation of chemicals. Environmental Toxicology and Pharmacology 11 (2002) 213-225
5. Bruning T., and Bolt H.M. Renal toxicity and carcinogenicity of trichloroethylene: Key results, mechanisms and controversies. Critical Reviews in Toxicology 30 3 (2000) 253-258
6. Bushnell P.J., Shafer T.J., Bale A.S., Boyes W.K., Simmons J.E., Eklund C., and Jackson T.L. Developing an exposure-dose-response model for the acute neurotoxicity of organic solvents: Overview and progress on in vitro models and dosimetry. Environmental Toxicology and Pharmacology 19 (2005) 607-614
7. Combes R.D. Assessing risk to humans from chemical exposure by using non-animal test data. Toxicology in Vitro 19 (2005) 921-924
8. Croute F., Pinsot J., Gaubin Y., Beau B., Simon V., Torres L., and Soleilhavoup J.P. Evaluation of the cytotoxic threshold of benzene and its chlorinated derivatives and related stress protein expression (Hsp72, Hsp90 and Grp78) in human cell in vitro. Fresenius Environmental Bulletin 9 (2000) 373-380
9. Croute F., Poinsot J., Gaubin Y., Beau B., Simon V., Murat J.C., and Soleilhavoup J.P. Volatile organic compounds cytotoxicity and expression of Hsp72, Hsp90 and Grp78 stress proteins in cultured human cells. Biochemica et Biophysica Acta 50 (2002) 147-155
10. Davila J.C., Rodriguez R.J., Melchert R.B., and Acosta D. Predictive value of in vitro model systems in toxicology. Annual Review of Pharmacology and Toxicology 38 (1998) 63-96
11. DeJongh J., Verhaar H.J.M., and Hermens J.L.M. Role of kinetics in acute lethality of nonreactive volatile organic compounds (VOCs). Toxicological Sciences 45 (1998) 26-32
12. DeJongh J., Forsby A., Houston J.B., Beckman M., Combes R., and Blaauboer B.J. An integrated approach to the prediction of systemic toxicity using computer-based biokinetic models and biological in vitro test methods: Overview of a prevalidation study based on the ECITTS project. Toxicology In Vitro 13 (1999) 549-554
13. Dreiem A., Myhre O., and Fonnum F. Relationship between lipophilicity of C6-10 hydrocarbon solvents and their ROS-inducing potency in rat cerebellar granule cells. NeuroToxicology 23 (2002) 701-709
14. Dreiem A., Myhre O., and Fonnum F. Involvement of the extracellular signal regulated kinase pathway in hydrocarbon-induced reactive oxygen species formation in human neutrophil granulocytes. Toxicology and Applied Pharmacology 190 2 (2003) 102-110
15. Eisenbrand G., Pool-Zobel B., Baker V., Balls M., Blaauboer B.J., Boobis A., Carere A., Kevekordes S., Pieters R., and Kleiner J. Methods of in vitro toxicology. Food and Chemical Toxicology 40 (2002) 193-236
16. Engelke M., Tahti H., and Vaalavirta L. Perturbation of artificial and biological membranes by organic compounds of aliphatic. alicyclic and aromatic structures. Toxicology in Vitro 10 (1996) 111-115
17. Gaskell M. Comparison of mutagenic activity of the benzene metabolites, hydroquinone and para-benzoquinone in the supF forward mutation assay: A role for minor DNA adducts formed from hydroquinone in benzene mutagenicity. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 554 1-2 (2004) 387-398
18. Gonzalez R.J., and Tarloff J.B. Expression and activities of several drug-metabolizing enzymes in LLC-PK1 cells. Toxicology in Vitro 18 (2004) 887-894
19. Guitart R., Puigdemont A., and Arboix M. Rapid headspace gas chromatographic method for the determination of liquid/gas partition coefficients. Journal of Chromatography 491 (1989) 271-280
20. Gülden M., and Seibert H. In vitro-in vivo extrapolation: estimation of human serum concentrations of chemicals equivalent to cytotoxic concentrations in vitro. Toxicology 189 (2003) 211-222
21. Hsieh G.C., Saito I., Kamijima M., Yu X., Shibata E., Toida M., and Takeuchi Y. Immunotoxicological evaluation of toluene exposure via drinking water in mice. Environmental Research 49 (1989) 93-96
22. Karakaya A., Yucesoy B., Burgaz S., Sabir H.U., and Karakaya A.E. Some immunological parameters in workers occupationally exposed to n-hexane. Human Experimental Toxicology 15 (1996) 56-58
23. Kolb B., and Ettre L.S. Static Headspace Gas Chromatography: Theory and Practice (1997), Wiley-VCH, Inc. pp. 45-115
24. Lee C.C., Liao J.W., and King J.J. Motorcycle exhaust particles induce airway inflammation and airway hyperresponsiveness in BALB/C mice. Toxicological Science 79 2 (2004) 326-334
25. McIntosh J.M., and Heffron J.J.A. Modelling alterations in the partition coefficient in in vitro biological systems using headspace gas chromatography. Journal of Chromatography B 738 (2000) 207-216
26. Perbellini L., Brugnone F., Caretta D., and Maranelli G. MEK exposure in industrial workers - Uptake and kinetics. International Archives in Occupational and Environmental Health 54 (1984) 73-81
27. Ridgway P., Nixon T.E., and Leach J.P. Occupational exposure to organic solvents and long-term nervous system damage detectable by brain imaging, neurophysiology or histopathology. Food and Chemical Toxicology 41 (2003) 153-187
28. Rogers J.V., Siegel G.L., Pollard D.L., Rooney A.D., and McDougal J.N. The cytotoxicity of volatile JP-8 jet fuel components in keratinocytes. Toxicology 197 2 (2004) 112-120
29. Santos C.R.d., Passarelli M.M., and Nascimento E.d. Evaluation of 2,5-hexanedione in urine of workers exposed to n-hexane in Brazilian shoe factories. Journal of Chromatography B 778 (2002) 237-244
30. Sato A., and Nakajima T. Water/air, blood/air, oil/air, oil/water and oil/blood partition coefficients of some aromatic hydrocarbons. Japanese Journal of Industrial Health 19 (1977) 132-136
31. Sato A., and Nakajima T. Partition coefficients of some aromatic hydrocarbons and ketones in water, blood and oil. British. Journal of Industrial Medicine 36 3 (1979) 231-234
32. Sikkema J., deBont J.A.M., and Poolman B. Interaction of cyclic hydrocarbons with biological membranes. The Journal of Biological Chemistry 29 (1994) 8022-8028
33. Wallace L. Major sources of exposure to benzene and other volatile organic chemicals. Risk Analysis 10 1 (1990) 59-64
34. Wichmann G., Mühlenberg J., Fischäder G., Kulla C., Rehwagen M., Herbarth O., and Lehmann I. An experimental model for the determination of immunomodulating effects by volatile compounds. Toxicology in Vitro 19 (2005) 685-693
35. Yang J.H., Lee C.H., Monteiro-Riviere N.A., Riviere J.E., Tsang A.L., and Chou C.C. Toxicity of jet fuel aliphatic and aromatic hydrocarbon mixtures on human epidermal Keratinocytes: Evaluation based on in vitro cytotoxicity and interleukin-8 release. Archives of Toxicology 80 8 (2006) 508-523
36. Zapor L., Skowron J., and Golofit-Szymczak M. The cytotoxicity of some organic solvents on isolated hepatocytes in monolayer cultures. International Journal of Occupational Safety and Ergonomics 8 1 (2002) 121-129
37. Zucco F., DeAngelis I., Testai E., and Stammati A. Toxicology investigations with cell culture systems: 20 years after. Toxicology in Vitro 18 (2004) 153-163