Neurological sequelae of intrauterine warfarin exposure

Journal of Clinical Neuroscience

Volumn 14, Issue 2, 2007, Pages 99-103

  Raghav, Sanjay ^a   Reutens, David ^a  

^a MONASH MEDICAL CENTRE   (Australia)

Author keywords

Cervical myelopathy; Pregnancy complications; Warfarin embryopathy

Indexed keywords

WARFARIN;

ADULT; ANAMNESIS; BONE DISEASE; CASE REPORT; DEEP VEIN THROMBOSIS; EMBRYOPATHY; HEARING DISORDER; HEARING LOSS; HUMAN; HYPOPLASIA; INTELLECTUAL IMPAIRMENT; KYPHOSIS; LANGUAGE DISABILITY; MALE; NEUROLOGIC DISEASE; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSICAL EXAMINATION; PRENATAL EXPOSURE; PRIORITY JOURNAL; REVIEW; SPINAL CORD COMPRESSION;

ABNORMALITIES, DRUG-INDUCED; ADULT; ANTICOAGULANTS; COGNITION DISORDERS; DEAFNESS; HUMANS; MALE; NASAL BONE; SPINAL CORD DISEASES; SPINE; WARFARIN;

EID: 33845220971     PISSN: 09675868     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jocn.2006.03.031     Document Type: Review

References (44)

1. Hall J.G., Pauli R.M., and Wilson K.M. Maternal and fetal sequelae of anticoagulation during pregnancy. Am J Med 68 (1980) 122-140
2. Whitfield M.F. Chondrodysplasia punctata after warfarin in early pregnancy. Case report and summary of the literature. Arch Dis Child 55 (1980) 139-142
3. Quenneville G., Barton B., McDevitt E., et al. The use of anticoagulants for thrombophlebitis during pregnancy. Am J Obstet Gynecol 77 (1959) 1135-1149
4. Jennings J.A., and Hodgkinson C.P. Anticoagulation for pulmonary embolism in pregnancy. Obstet Gynecol 24 (1964) 85-88
5. DiSaia P. Pregnancy and delivery of a patient with a Starr-Edwards mitral valve prosthesis. Obstetrics and Gynecology 28 (1966) 469-472
6. Furie B., and Furie B.C. Molecular basis of vitamin K-dependent gamma-carboxylation. Blood 75 (1990) 1753-1762
7. Lee H.C., Cho S.Y., Lee H.J., et al. Warfarin-associated fetal intracranial hemorrhage: a case report. J Korean Med Sci 18 (2003) 764-767
8. Warkany J. Warfarin embryopathy. Teratology 14 (1976) 205-209
9. Otawara Y., and Price P.A. Developmental appearance of matrix GLA protein during calcification in the rat. J Biol Chem 261 (1986) 10828-10832
10. Howe A.M., Lipson A.H., de Silva M., et al. Severe cervical dysplasia and nasal cartilage calcification following prenatal warfarin exposure. Am J Med Genet 71 (1997) 391-396
11. Takano H., Smith W.L., Sato Y., et al. Cervical spine abnormalities and instability with myelopathy in warfarin-related chondrodysplasia: 17-year follow-up. Pediatr Radiol 28 (1998) 497-499
12. Holzgreve W., Carey J.C., and Hall B.D. Warfarin-induced fetal abnormalities. Lancet 2 (1976) 914-915
13. Kaplan L.C., Anderson G.G., and Ring B.A. Congenital hydrocephalus and Dandy-Walker malformation associated with warfarin use during pregnancy. Birth Defects Orig Artic Ser 18 (1982) 79-83
14. Kaplan L.C. Congenital Dandy Walker malformation associated with first trimester warfarin: a case report and literature review. Teratology 32 (1985) 333-337
15. Kerber I.J., Warr III O.S., and Richardson C. Pregnancy in a patient with a prosthetic mitral valve. Associated with a fetal anomaly attributed to warfarin sodium. JAMA 203 (1968) 223-225
16. Pettifor J.M., and Benson R. Congenital malformations associated with the administration of oral anticoagulants during pregnancy. J Pediatr 86 (1975) 459-462
17. Tejani N. Anticoagulant therapy with cardiac valve prosthesis during pregnancy. Obstet Gynecol 42 (1973) 785-793
18. Kulman J.D., Harris J.E., Haldeman B.A., et al. Primary structure and tissue distribution of two novel proline-rich gamma-carboxyglutamic acid proteins. Proc Natl Acad Sci USA 94 (1997) 9058-9062
19. Prieto A.L., Weber J.L., Tracy S., et al. Gas6, a ligand for the receptor protein-tyrosine kinase Tyro-3, is widely expressed in the central nervous system. Brain Res 816 (1999) 646-661
20. Fridell Y.W., Villa Jr. J., Attar E.C., et al. GAS6 induces Axl-mediated chemotaxis of vascular smooth muscle cells. J Biol Chem 273 (1998) 7123-7126
21. Li J., Lin J.C., Wang H., et al. Novel role of vitamin k in preventing oxidative injury to developing oligodendrocytes and neurons. J Neurosci 23 (2003) 5816-5826
22. Carrie I., Portoukalian J., Vicaretti R., et al. Menaquinone-4 concentration is correlated with sphingolipid concentrations in rat brain. J Nutr 134 (2004) 167-172
23. Sundaram K.S., and Lev M. Warfarin administration reduces synthesis of sulfatides and other sphingolipids in mouse brain. J Lipid Res 29 (1988) 1475-1479
24. Denisova N.A., and Booth S.L. Vitamin K and sphingolipid metabolism: evidence to date. Nutr Rev 63 (2005) 111-121
25. Ashour Z.A., Shawky H.A., and Hassan Hussein M. Outcome of pregnancy in women with mechanical valves. Tex Heart Inst J 27 (2000) 240-245
26. Ben Ismail M., Abid F., Trabelsi S., et al. Cardiac valve prostheses, anticoagulation, and pregnancy. Br Heart J 55 (1986) 101-105
27. Pavankumar P., Venugopal P., Kaul U., et al. Pregnancy in patients with prosthetic cardiac valve. A 10-year experience. Scand J Thorac Cardiovasc Surg 22 (1988) 19-22
28. Al-Lawati A.A., Venkitraman M., Al-Delaime T., et al. Pregnancy and mechanical heart valve replacement; dilemma of anticoagulation. Eur J Cardiothorac Surg 22 (2002) 223-227
29. Chan W.S., Anand S., and Ginsberg J.S. Anticoagulation of pregnant women with mechanical heart valves: a systematic review of the literature. Arch Intern Med 160 (2000) 191-196
30. Vitale N., De Feo M., and Cotrufo M. Anticoagulation for prosthetic heart valves during pregnancy: the importance of warfarin daily dose. Eur J Cardiothorac Surg 22 (2002) 656 author reply 657
31. Bates S.M., Greer I.A., Hirsh J., et al. Use of antithrombotic agents during pregnancy: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest 126 (2004) 627S-644S
32. Hurwitz A., Milwidsky A., Medina A., et al. Failure of continuous intravenous heparinization to prevent stroke in a pregnant woman with a prosthetic valve and atrial fibrillation. A case report. J Reprod Med 30 (1985) 618-620
33. Golby A.J., Bush E.C., DeRook F.A., et al. Failure of high-dose heparin to prevent recurrent cardioembolic strokes in a pregnant patient with a mechanical heart valve. Neurology 42 (1992) 2204-2206
34. Sbarouni E., and Oakley C.M. Outcome of pregnancy in women with valve prostheses. Br Heart J 71 (1994) 196-201
35. Watson W.J., Freeman J., O'Brien C., et al. Embolic stroke in a pregnant patient with a mechanical heart valve on optimal heparin therapy. Am J Perinatol 13 (1996) 371-372
36. Ginsberg J.S., Chan W.S., Bates S.M., et al. Anticoagulation of pregnant women with mechanical heart valves. Arch Intern Med 163 (2003) 694-698
37. de Valk H.W., Banga J.D., Wester J.W., et al. Comparing subcutaneous danaparoid with intravenous unfractionated heparin for the treatment of venous thromboembolism. A randomized controlled trial. Ann Intern Med 123 (1995) 1-9
38. Gould M.K., Dembitzer A.D., Doyle R.L., et al. Low-molecular-weight heparins compared with unfractionated heparin for treatment of acute deep venous thrombosis. A meta-analysis of randomized, controlled trials. Ann Intern Med 130 (1999) 800-809
39. Dolovich L.R., Ginsberg J.S., Douketis J.D., et al. A meta-analysis comparing low-molecular-weight heparins with unfractionated heparin in the treatment of venous thromboembolism: examining some unanswered questions regarding location of treatment, product type, and dosing frequency. Arch Intern Med 160 (2000) 181-188
40. Sherman S., and Hall B.D. Warfarin and fetal abnormality. Lancet 1 (1976) 692
41. Pauli R.M., Madden J.D., Kranzler K.J., et al. Warfarin therapy initiated during pregnancy and phenotypic chondrodysplasia punctata. J Pediatr 88 (1976) 506-508
42. Carson M., and Reid M. Letter: Warfarin and fetal abnormality. Lancet 1 (1976) 1356
43. Gooch W.M., and Parvey L.S. Warfarin embryopathy: longitudinal and postmortem examination. Clinical Research 26 (1978) 74A
44. Pati S., and Helmbrecht G.D. Congenital schizencephaly associated with in utero warfarin exposure. Reprod Toxicol 8 (1994) 115-120