Sequential designs for logistic phase I clinical trials

Journal of Biopharmaceutical Statistics

Volumn 16, Issue 5, 2006, Pages 605-621

  Liu, Guohui ^a,e   Rosenberger, William F ^a,b,c   Haines, Linda M ^d  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c GEORGE MASON UNIVERSITY   (United States)

^d UNIVERSITY OF CAPE TOWN   (South Africa)

^e MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

Logit model; Maximum tolerated dose; Sequential design

Indexed keywords

DRUG;

ARTICLE; CLINICAL RESEARCH; CLINICAL TRIAL; DOSE CALCULATION; DOSE RESPONSE; DRUG RESEARCH; HUMAN; MAXIMUM LIKELIHOOD METHOD; MAXIMUM TOLERATED DOSE; MEDICAL ETHICS; NONPARAMETRIC TEST; PARAMETRIC TEST; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; SEQUENTIAL ANALYSIS; SIMULATION; STATISTICAL MODEL;

ALGORITHMS; CLINICAL TRIALS, PHASE I; COMPUTER SIMULATION; HUMANS; LOGISTIC MODELS; MODELS, STATISTICAL; RESEARCH DESIGN;

EID: 33751584850     PISSN: 10543406     EISSN: 15205711     Source Type: Journal    
DOI: 10.1080/10543400600860337     Document Type: Article

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