Clinical significance of evaluation of serum zinc concentrations in C-viral chronic liver disease

Digestive Diseases and Sciences

Volumn 51, Issue 11, 2006, Pages 1967-1977

  Moriyama, Mitsuhiko ^a   Matsumura, Hiroshi ^a   Fukushima, Akiko ^a   Ohkido, Kenji ^a   Arakawa, Yasuo ^a   Nirei, Kazushige ^a   Yamagami, Hiroaki ^a   Kaneko, Miki ^a   Tanaka, Naohide ^a   Arakawa, Yasuyuki ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Chronic hepatitis C; Cumulative incidence of HCC development; Hepatocellular carcinoma (HCC); Liver cirrhosis; Multivariate analysis; Zinc

Indexed keywords

ALBUMIN; HEPATITIS C ANTIBODY; VIRUS RNA; ZINC;

ADULT; AGED; ALBUMIN BLOOD LEVEL; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; CANCER PATIENT; CANCER SURVIVAL; CHRONIC HEPATITIS; CHRONIC LIVER DISEASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; EVALUATION; FEMALE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RNA ANALYSIS; SURVIVAL RATE; SYMPTOM; THROMBOCYTE COUNT; TUMOR VOLUME; VIRUS CARRIER; ZINC BLOOD LEVEL;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; FEMALE; FERRITINS; FIBROSIS; HEPATITIS C; HUMANS; LIVER CIRRHOSIS; LIVER DISEASES; LIVER NEOPLASMS; MALE; MIDDLE AGED; ZINC;

EID: 33751541159     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-005-9051-7     Document Type: Article

References (32)

1. Dibley MJ (2002) Present knowledge in nutrition, 18th ed. Kenpakusha, Tokyo, pp 344-345
2. Krebs NF (2000) Overview of zinc absorption and excretion in the human gastrointestinal tract. J Nutr 130(Suppl 5):1374S-137S
3. Yoshikawa T, Naito Y, Tanigawa T, Yoneta T, Yasuda M, Ueda S, Oyamada H, Kondo M (1991) Effect of zinc-carnosine chelate compound (Z-103), a novel antioxidant, on acute gastric mucosal injury induced by ischemia-reperfusion in rats. Free Radic Res Commun 14(4):289-296
4. Handa O, Yoshida N, Tanaka Y, Ueda M, Ishikawa T, Takagi T, Matsumoto N, Naito Y, Yoshikawa T (2002) Inhibitory effect of polaprezinc on the inflammatory response to Helicobacter pylori. Can J Gastroenterol 16(11):785-789
5. Yoshikawa T, Yamaguchi T, Yoshida N, Yamamoto H, Kitazumi S, Takahashi S, Naito Y, Kondo M (1997) Effect of Z-103 on TNB-induced colitis in rats. Digestion 58(5):464-468
6. Ferahman M, Unal E, Sakoglu N, Ersoy YE, As A, Ozdemir S (2003) Zinc and copper status in acute pancreatitis: an experimental study. Biol Trace Elem Res 91(1):89-94
7. Takagi H, Nagamine T, Abe T, Takayama H, Sato K, Otsuka T, Kakizaki S, Hashimoto Y, Matsumoto T, Kojima A, Takezawa J, Suzuki K, Sato S, Mori M (2001) Zinc supplementation enhances the response to interferon therapy in patients with chronic hepatitis C. J Viral Hepat 8(5):367-371
8. Ebara M, Fukuda H, Hatano R, Yoshikawa M, Sugiura N, Saisho H, Kondo F, Yukawa M (2003) Metal contents in the liver of patients with chronic liver disease caused by hepatitis C virus. Reference to hepatocellular carcinoma. Oncology 65(4):323-330
9. Riggio O, Merli M, Capocaccia L (1992) Zinc supplementation reduce blood ammonia and increases liver ornithin transcarbamirase activity in experimental cirrhosis. Hepatology 16:785-789
10. Muranaka H, Kato N (1969) Detection of serum zinc by atomic absorption spectrometry. Rinsho Byori 17:559-562 (in Japanese)
11. Oka S, Ogino K, Matsuura S, Yoshimura S, Yamamoto K, Okazaki Y, Takemoto T, Kato N, Uda T (1989) Human serum immunoreactive copper, zinc-superoxide dismutase assayed with an enzyme monoclonal immunosorbent in patients with digestive cancer. Clin Chim Acta 182(2):209-219
12. Matsumura H, Moriyama M, Goto I, Tanaka N, Okubo H, Arakawa Y (2000) Natural course of progression of liver fibrosis in patients with chronic liver disease type C in Japan - A study of 527 patients at one establishment in Japan. J Viral Hepat 7:375-381
13. Ono E, Shiratori Y, Okudaira T, Imamura M, Teratani T, Kanai F, Kato N, Yoshida H, Shiina S, Omata M (1999) Platelet count reflects stage of chronic hepatitis C. Hepatol Res 15:192-200
14. Moriyama M, Matsumura H, Aoki H, Shimizu T, Nakai K, Saito T, Yamagami H, Shioda A, Kaneko M, Goto I, Tanaka N, Arakawa Y (2003) Long-term outcome, with monitoring of platelet counts, in patients with chronic hepatitis C and liver cirrhosis after interferon therapy. Intervirology 46:296-307
15. Okamoto H, Sugiyama Y, Okada S, Kurai K, Akahane Y, Sugai Y, Tanaka T, Tanaka T, Sato K, Tsuda F, Miyakawa Y, Mayumi M (1992) Typing of hepatitis C virus by PCR with type-specific primers: application to clinical surveys and tracing infectious sources. J Gen Virol 73:673-679
16. Simmonds P, Alberti A, Alter HJ, Bonino F, Bradley DW, Brechot C, Brouwer JT, Chan SW, Chayama K, Chen DS, Choo QL, Colombo M, Cuypers HTM, Date T, Dusheiko GM, Esteban JI, Fay O, Hadziyannis SJ, Han J, Hatzakis A, Holmes EC, Hotta H, Houghton M, Irvine B, Kohara M, Kolberg JA, Kuo G, Lau JYN, Lelie PN, Maertens G, McOmish F, Miyamura T, Mizokami M, Nomoto A, Prince AM, Reesink HW, Rice C, Roggendorf M, Schalm SW, Shikata T, Shimotohno K, Stuyver L, Trepo C, Weiner A, Yap PL, Urdea MS (1994) A proposed system for the nomenclature of hepatitis C viral genotypes. Hepatology 19:1321-1324
17. Levy I, Sherman M, the Liver Cancer Study Group of the University of Toronto (2002) Staging of hepatocellular carcinoma: assessment of the CLIP, Okuda, and Child-Pugh staging systems in a cohort of 257 patients in Toronto. Gut 50:881-885
18. Boyett JD, Sullivan JF (1970) Distribution of protein-bound zinc in normal and cirrhotic serum. Metabolism 19(2):148-157
19. Boyett JD, Sullivan JF (1970) Zinc and collagen content of cirrhotic liver. Am J Dig Dis 15(9):797-802
20. Scholmerich J, Becher MS, Kottgen E, Rauch N, Haussinger D, Lohle E, Vuilleumier JP, Gerok W (1983) The influence of portosystemic shunting on zinc and vitamin A metabolism in liver cirrhosis. Hepatogastroenterology 30(4):143-147
21. Wakiyama K, Arakawa Y, Suzuki T, Miyamoto M, Matsuo Y, Honda T, Tomioka E, Mano M, Kigoshi K, Sasaki A, Takeuchi S (1986) A pathophysiological significance of trace metals in rats with experimental cirrhosis. Acta Pathol Hepatica 140:1182-1183 (In Japanese)
22. Evans GW, Winter TW (1975) Zinc transport by transferrin in rat portal blood plasma. Biochem Biophys Res Commun 66(4):1218-1224
23. Evans GW (1976) Transferrin function in zinc absorption and transport. Proc Soc Exp Biol Med 151(4):775-778
24. Fisher GL (1975) Function and homeostasis of copper and zinc in mammals. Sci Total Environ 4(4):373-412
25. Vargaftig BB, Tranier Y, Chignard M (1975) Blockade by metal complexing agents and by catalase of the effects of arachidonic acid on platelets: relevance to the study of anti-inflammatory mechanisms. Eur J Pharmacol 33:19-29
26. Nagasue N, Kolno H, Chang YC, Nakamura T (1989) Iron, copper and zinc levels in serum and cirrhotic liver of patients with and without hepatocellular carcinoma. Oncology 46:293-296
27. Ebara M, Fukuda H, Hatano R, Saisho H, Nagato Y, Suzuki K, Nakajima K, Yukawa M, Kondo F, Nakayama A, Sakurai H (2000) Relationship between copper, zinc and metallothionein in hepatocellular carcinoma and its surrounding liver parenchyma. J Hepatol 33(3):415-422
28. Stempniak M, Hostomska Z, Nodes BR, Hostomsky Z (1997) The NS3 proteinase domain of hepatitis C virus is a zinc-containing enzyme. J Virol 71(4):2881-2886
29. Love RA, Parge HE, Wickersham JA, Hostomsky Z, Habuka N, Moomaw EW, Adachi T, Hostomska Z (1996) The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site. Cell 87(2):331-342
30. Tellinghuisen TL, Marcotrigiano J, Gorbalenya AE, Rice CM (2004) The NS5A protein of hepatitis C virus is a zinc metalloprotein. J Biol Chem 279(47):48576-48587
31. Jiang Y, Kang YJ (2004) Metallothionein gene therapy for chemical-induced liver fibrosis in mice. Mol Ther 10:1130-1139
32. Camps J, Bargallo T, Gimenez A, Alie S, Caballeria J, Pares A, Joven J, Masana L, Rodes J (1992) Relationship between hepatic lipid peroxidation and fibrogenesis in carbon tetrachloride-treated rats: effect of zinc administration. Clin Sci (Lond) 83:695-700