Testing effective connectivity changes with structural equation modeling: What does a bad model tell us?

Human Brain Mapping

Volumn 27, Issue 12, 2006, Pages 935-947

  Protzner, Andrea B ^a   McIntosh, Anthony R ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b ROTMAN RESEARCH INSTITUTE   (Canada)

Author keywords

Functional connectivity; Neuroimaging; Simulation; Statistics

Indexed keywords

ARTICLE; ARTIFICIAL NEURAL NETWORK; BRAIN MAPPING; NEUROANATOMY; NEUROIMAGING; PRIORITY JOURNAL; SIMULATION; STATISTICAL ANALYSIS; STRUCTURAL EQUATION MODELING; VALIDATION PROCESS;

ALGORITHMS; BRAIN MAPPING; COMPUTER SIMULATION; HUMANS; MODELS, NEUROLOGICAL; MODELS, STATISTICAL; NERVE NET;

EID: 33751517490     PISSN: 10659471     EISSN: None     Source Type: Journal    
DOI: 10.1002/hbm.20233     Document Type: Article

References (32)

1. Bentler PM (1985): Theory and implementation of EQS, a structural equations program. Los Angeles: BMDP Statistical Software.
2. Bentler PM, Weeks DG (1980): Linear structural equations with latent variables. Psychometrics 45:289-308.
3. Bollen KA (1989): Structural equations with latent variables. New York: John Wiley & Sons.
4. Buchel C, Friston K (1997): Modulation of connectivity in visual pathways by attention: cortical interactions evaluated with structural equation modeling and fMRI. Cereb Cortex 7:768-778.
5. Bullmore E, Horwitz B, Honey G, Brammer M, Williams S, Sharma T (2000): How good is good enough in path analysis of fMRI data? Neuroimage 11:289-301.
6. Friston K (1994): Functional and effective connectivity: a synthesis. Hum Brain Mapp 2:56-78.
7. Friston KJ, Harrison L, Penny W (2003): Dynamic causal modelling. Neuroimage 19:1273-1302.
8. Goncalves MS, Hall DA (2003): Connectivity analysis with structural equation modelling: an example of the effects of voxel selection. Neuroimage 20:1455-1467.
9. Goncalves MS, Hall DA, Johnsrude IS, Haggard MP (2001): Can meaningful effective connectivities be obtained between auditory cortical regions? Neuroimage 14:1353-1360.
10. Grady CL, McIntosh AR, Craik FI (2003): Age-related differences in the functional connectivity of the hippocampus during memory encoding. Hippocampus 13:572-586.
11. Hayduk L (1987): Structural equation modeling with LISREL. Baltimore: Johns Hopkins University Press.
12. Horwitz B (2003): The elusive concept of brain connectivity. Neuroimage 19:466-470.
13. Horwitz B, McIntosh AR, Haxby JV, Furey M, Salerno JA, Schapiro MB, Rapoport SI, Grady CL (1995): Network analysis of PET-mapped visual pathways in Alzheimer type dementia. Neuroreport 6:2287-2292.
14. Jennings JM, McIntosh AR, Kapur S, Zipursky RB, Houle S (1998): Functional network differences in schizophrenia: a rCBF study of semantic processing. Neuroreport 9:1697-1700.
15. Joreskog K, Sorbom D (1979): Advances in factor analysis and structural equation models. Cambridge, MA: Abt Publishers.
16. Joreskog KG, Sorbom D (1984): LISREL VI: user's guide, 3rd ed. Mooresville, IN: Scientific Software.
17. Kohler S, McIntosh AR, Moscovitch M, Winocur G (1998): Functional interactions between the medial temporal lobes and posterior neocortex related to episodic memory retrieval. Cereb Cortex 8:451-461.
18. Lee L, Harrison LM, Mechelli A (2003): A report of the functional connectivity workshop, Dusseldorf 2002. Neuroimage 19:457-465.
19. Loehlin JC (1987): Latent variable models. An introduction to factor, path, and structural analysis. Hillsdale, NJ: Lawrence Erlbaum.
20. MacCallum R (1995): Model specification: procedures, strategies, and related issues. In: Hoyle RH, editor. Structural equation modelling: concepts, issues, and applications. Thousand Oak, CA: Sage. p 16-36.
21. Maguire EA, Mummery CJ, Buchel C (2000): Patterns of hippocampal-cortical interaction dissociate temporal lobe memory subsystems. Hippocampus 10:475-482.
22. McIntosh AR (1999): Mapping cognition to the brain through neural interactions. Memory 7:523-548.
23. McIntosh AR, Gonzalez-Lima F (1992): Structural modeling of functional visual pathways mapped with 2-deoxyglucose: effects of patterned light and footshock. Brain Res 578:75-86.
24. McIntosh AR, Gonzalez-Lima F (1993): Network analysis of functional auditory pathways mapped with fluorodeoxyglucose: associative effects of a tone conditioned as a Pavlovian excitor or inhibitor. Brain Res 627:129-140.
25. McIntosh AR, Gonzalez-Lima F (1994): Structural equation modeling and its application to network analysis in functional brain imaging. Hum Brain Mapp 2:2-22.
26. McIntosh AR, Grady CL, Ungerleider LG, Haxby JV, Rapoport SI, Horwitz B (1994): Network analysis of cortical visual pathways mapped with PET. J Neurosci 14:655-666.
27. McIntosh AR, Grady CL, Haxby JV, Ungerleider LG, Horwitz B (1996): Changes in limbic and prefrontal functional interactions in a working memory task for faces. Cereb Cortex 6:571-584.
28. McIntosh AR, Cabeza RE, Lobaugh NJ (1998): Analysis of neural interactions explains the activation of occipital cortex by an auditory stimulus. J Neurophysiol 80:2790-2796.
29. Northoff G, Kotter R, Baumgart F, Danos P, Boeker H, Kaulisch T, Schlagenhauf F, Walter H, Heinzel A, Witzel T, Bogerts B (2004): Orbitofrontal cortical dysfunction in akinetic catatonia: a functional magnetic resonance imaging study during negative emotional stimulation. Schizophr Bull 30:405-427.
30. Schlosser R, Gesierich T, Kaufmann B, Vucurevic G, Hunsche S, Gawehn J, Stoeter P (2003): Altered effective connectivity during working memory performance in schizophrenia: a study with fMRI and structural equation modeling. Neuroimage 19:751-763.
31. Solodkin A, Hlustik P, Chen EE, Small SL (2004): Fine modulation in network activation during motor execution and motor imagery. Cereb Cortex 14:1246-1255.
32. Zhuang J, LaConte S, Peltier S, Zhang K, Hu X (2005): Connectivity exploration with structural equation modeling: an fMRI study of bimanual motor coordination. Neuroimage 25:462-470.