Stimulation with 0,3 mg recombinant human thyrotropin (rhTSH) increases the effect of 131 I therapy in patients with nontoxic nodular goiter. A prospective, randomized, double-blind trial - Secondary publication;Stimulation med 0,3 mg rekombinant human thyrotropin øger effekten af 131I- behandling hos patienter med atoksisk nodulær struma. En prospektiv, randomiseret, dobbeltblindet undersøgelse - Sekundærpublikation

Ugeskrift for Laeger

Volumn 168, Issue 47, 2006, Pages 4098-4101

  Nielsen, Viveque Egsgaard ^a   Bonnema, Steen Joop ^a   Boel Jørgensen, Henrik ^a   Grupe, Peter ^a   Hegedüs, Laszlo ^a  

^a ODENSE UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

IODINE 131; PLACEBO; RECOMBINANT THYROTROPIN;

ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG POTENTIATION; HUMAN; HYPOTHYROIDISM; MAJOR CLINICAL STUDY; NODULAR GOITER; PATIENT SATISFACTION; RANDOMIZED CONTROLLED TRIAL; THYROID FUNCTION; TREATMENT OUTCOME; TREATMENT RESPONSE;

EID: 33751427000     PISSN: 00415782     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Hegedüs L, Bonnema SJ, Bennedbaek FN. Management of simple nodular goiter: current status and future perspectives. Endocr Rev 2003;24:102-32.
2. Nielsen VE, Bonnema SJ, Hegedüs L. The effects of recombinant human thyrotropin, in normal subjects and patients with goitre. Clin Endocrinol (Oxf) 2004;61:655-63.
3. Albino CC, Mesa CO, Jr., Olandoski M et al. Recombinant human thyrotropin as adjuvant in the treatment of multinodular goiters with radioiodine. J Clin Endocrinol Metab 2005;90:2775-80.
4. Cohen O, Ilany J, Hoffman C et al. Low-dose recombinant human thyrotropinaided radioiodine treatment of large, multinodular goiters in elderly patients. Eur J Endocrinol 2006;154:243-52.
5. Nieuwlaat WA, Huysmans DA, van den Bosch HC et al. Pretreatment with a single, low dose of recombinant human thyrotropin allows dose reduction of radioiodine therapy in patients with nodular goiter. J Clin Endocrinol Metab 2003;88:3121-9.
6. Silva MNC, Rubio IGS, Romao R et al. Administration of a single dose of recombinant human Thyrotropin enhances the efficacy of radioiodine treatment of large compressive multinodular goitres. Clin Endocrinol (Oxf) 2004;59:1-9.
7. Nielsen VE, Bonnema SJ, Boel-Jørgensen H et al. Recombinant human thyrotropin markedly changes the 131I kinetics during 131I therapy of patients with nodular goiter: an evaluation by a randomized double-blinded trial. J Clin Endocrinol Metab 2005;90:79-83.
8. Nielsen VE, Bonnema SJ, Hegedüs L. Effects of 0.9 mg recombinant human TSH on thyroid size and function, in normal subjects. J Clin Endocrinol Metab 2004;89:2242-7.
9. Nielsen VE, Bonnema SJ, Hegedüs L. Transient goiter enlargement after administration of 0.3 mg recombinant human thyrotropin (rhTSH) in patients with benign nontoxic nodular goiter. J Clin Endocrinol Metab 2006;91:1317-22.