Pretreatment with a single, low dose of recombinant human thyrotropin allows dose reduction of radioiodine therapy in patients with nodular goiter

Journal of Clinical Endocrinology and Metabolism

Volumn 88, Issue 7, 2003, Pages 3121-3129

  Nieuwlaat, Willy Anne ^a,b   Huysmans, Dyde A ^a   Van Den Bosch, Harrie C ^a   Sweep, C G ^b   Ross, H Alec ^b   Corstens, Frans H ^b   Hermus, Ad R ^b  

^a CATHARINA HOSPITAL   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

IODINE 123; IODINE 131; RADIOACTIVE IODINE; RECOMBINANT THYROTROPIN; THYROTROPIN; THYROTROPIN RECEPTOR ANTIBODY; THYROXINE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DRUG EFFICACY; DRUG SAFETY; DRUG UPTAKE; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; HYPERTHYROIDISM; LOW DRUG DOSE; MALE; NODULAR GOITER; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; THYROID FUNCTION; THYROID GLAND; THYROID SCINTISCANNING; THYROIDITIS; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; TRACHEA COMPRESSION; TREATMENT OUTCOME;

AGED; COMBINED MODALITY THERAPY; FEMALE; FOLLOW-UP STUDIES; GOITER, NODULAR; HUMANS; IODINE RADIOISOTOPES; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; RADIATION DOSAGE; RECOMBINANT PROTEINS; THYROID GLAND; THYROTROPIN;

EID: 0038637271     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2002-021554     Document Type: Article

References (21)

1. Hegedüs L, Hansen BM, Knudsen N, Hansen JM 1988 Reduction of size of thyroid with radioactive iodine in multinodular non-toxic goitre. Br Med J 297:661-662
2. Nygaard B, Hegedüs L, Gervil M, Hjalgrim H, Soe-Jensen P, Hansen JM 1993 Radioiodine treatment of multinodular non-toxic goitre. Br Med J 307:828-832.
3. Huysmans DAKC, Hermus ARMM, Corstens FHM, Barentsz JO, Kloppenborg PWC 1994 Large, compressive goiters treated with radioiodine. Ann Intern Med 121:757-762
4. 131I therapy in patients with non-toxic multinodular goiter. Eur J Endocrinol 132:86-87
5. de Klerk JMH, van Isselt JW, van Dijk A, Hakman ME, Pameijer FA, Koppeschaar HPF, Zelissen PMJ, van Schaik JPJ, van Rijk PP 1997 Iodine-131 therapy in sporadic nontoxic goiter. J Nucl Med 38:372-376
6. Bonnema SJ, Bertelsen H, Mortensen J, Andersen PB, Knudsen DU, Bastholt L, Hegedüs L 1999 The feasibility of high dose iodine 131 treatment as an alternative to surgery in patients with a very large goiter: effect on thyroid function and size and pulmonary function. J Clin Endocrinol Metab 84:3636-3641
7. Wesche MFT, Tiel-v Buul MMC, Lips P, Smits NJ, Wiersinga WM 2001 A randomized trial comparing levothyroxine with radioactive iodine in the treatment of sporadic nontoxic goiter. J Clin Endocrinol Metab 86:998-1005
8. Huysmans D, Hermus A, Edelbroek M, Barentz J, Corstens F, Kloppenborg P 1997 Radioiodine for nontoxic multinodular goiter. Thyroid 7:235-239
9. Hermus AR, Huysmans DA 1998 Treatment of benign nodular thyroid disease. N Engl J Med 338:1438-1447
10. 131I-treatment of multinodular nontoxic goiter evaluated by flow volume loop curves. J Endocrinol Invest 19:71-75
11. Huysmans DAKC, Buijs WCAM, van de Ven MTP, van den Broek WJM, Kloppenborg PWC, Hermus ARMM, Corstens FHM 1996 Dosimetry and risk estimates of radioiodine therapy for large, multinodular goiters. J Nucl Med 37:2072-2079
12. Huysmans DA, Nieuwlaat W-A, Erdtsieck RJ, Schellekens AP, Bus JW, Bravenboer B, Hermus AR 2000 Administration of a single, low dose of recombinant human thyrotropin significantly enhances thyroid radioiodide uptake in nontoxic nodular goiter. J Clin Endocrinol Metab 85:3592-3596
13. Nieuwlaat W-A, Hermus AR, Sivro-Prndelj F, Corstens FH, Huysmans DA 2001 Pretreatment with recombinant human thyrotropin changes the regional distribution of radioiodine on thyroid scintigrams of nodular goiters. J Clin Endocrinol Metab 86:5330-5336
14. 131I therapy of multinodular goitre. Clin Endocrinol (Oxf) 41:715-718
15. DeGroot LJ 1975 Graves' disease diagnosis and treatment. Multinodular goitre. In: DeGroot LJ, Stanbury JB, eds. The thyroid and its diseases. 4th ed. New York: Wiley; 314-367 and 637-665
16. Doering P, Kramer K 1958 Die Bestimmung des Schilddrüsengewichtes mit der Szintigraphie nach Gabe von Radiojod; Ein Beitrag zur Dosierung des Radioisotopes. Strahlenther 105:245-259
17. Huysmans DAKC, de Haas MM, van den Broek WJM, Hermus ARMM, Barentsz JO, Corstens FHM, Ruijs SHJ 1994 Magnetic resonance imaging for volume estimation of large multinodular goitres; a comparison with scintigraphy. Br J Radiol 67:519-523
18. Rohrer F 1915 Der Strömungswiderstand in den menschlichen Atemwegen und der EinfluB der unregelmäBigen Verzweigung des Bronchialsystems auf den Atmungsverlauf verscheidenen Lungenbezirken. Pflügers Arch ges Physiol 162:225-299
19. Le Moli R, Wesche MFT, Tiel-van Buul MMC, Wiersinga WM 1999 Determinants of long-term outcome of radioiodine therapy of sporadic non-toxic goitre. Clin Endocrinol (Oxf) 50:783-789
20. Huysmans DAKC, Hermus ARMM, Edelbroek MAL, Tjabbes T, Oostdijk A, Ross HA, Corstens FHM, Kloppenborg PWC 1997 Autoimmune hyperthyroidism occurring late after radioiodine treatment for volume reduction of large multinodular goiters. Thyroid 7:535-539
21. Verelst J, Bonnyns M, Glinoer D 1990 Radioiodine therapy in voluminous multinodular non-toxic goitre. Acta Endocrinol (Copenh) 122:417-421