Comparison of the solubility and dissolution rate of gliclazide-β-cyclodextrin inclusion complexes prepared by liquid/ liquid extraction and neutralization

Journal of Food and Drug Analysis

Volumn 14, Issue 3, 2006, Pages 230-235

  Lo, Yung Kuang ^a   Hsu, Chu Ping ^a   Tsai, Tong Rong ^a   Cham, Thau Ming ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cyclodextrin; Gliclazide; Liquid liquid extraction; Neutralization; Solubility

Indexed keywords

BETA CYCLODEXTRIN; GLICLAZIDE;

ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG MIXTURE; DRUG PURITY; DRUG SOLUBILITY; INFRARED SPECTROSCOPY; LIQUID LIQUID EXTRACTION; PARTICLE SIZE; STOICHIOMETRY;

EID: 33751374141     PISSN: 10219498     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Pitha, J., Milecki, J., Fales, H., Pannell, L., Uekama, K. 1986. Hydroxypropyl-β-cyclodextrin: preparation and characterization; effects on solubility of drugs. Int. J. Pharm. 29: 73-82.
2. Blanco, J., Vila-Jato, J.L., Otero, F., Anguiano, S. 1991. Influence of method of preparation on inclusion complexes of naproxen with different cyclodextrins. Drug Dev. Ind. Pharm. 17: 943-945.
3. Ammar, H.O., Ghorab, M., El-Nahhas, S.A., Emara, L.H., Makram, T.S. 1999. Inclusion complexation of furosemide in cyclodextrins. Pharmazie. 54: 142-144.
4. Andersen, F.A., Bundgaard, H. 1984. Inclusion complexation of metronidazole benzoate with β-cyclodextrin and its depression of anhydrate-hydrate transition in aqueous suspensions. Int. J. Pharm. 19: 189-197.
5. Chow, D., Karara, A. 1986. Characterization, dissolution and bioavailability in rats of ibuprofen-b-cyclodextrin complex system. Int. J. Pharm. 28: 95-101.
6. Bekers, O., Uijtendaal, E. V., Beijnen, J.H., Bult, A., Underberg, W.J.M. 1991. Cyclodextrins in pharmaceutical field. Drug Dev. Ind. Pharm. 17: 1503-1549.
7. Saenger, W. 1980. Cyclodextrin inclusion compounds in research and laboratory. Angew. Chem. Int. Ed. Engl. 19: 344-362.
8. Szejtli, J. 1998. Introduction and general overview of cyclodextrin chemistry. Chem. Rev. 98: 1743-1753.
9. Loftsson, T., Brewster, M.E. 1996. Pharmaceutical applications of cyclodextrins. I. Drug solubilisation and stabilization. J. Pharm. Sci. 85: 1012-1025.
10. Tessier, D., Dawson, K., Tetrault, J.P., Bravo, G., Meneilly, G.S. 1994. Glibenclamide vs gliclazide in type 2 diabetes of the elderly. Diabet. Med. 11: 974-980.
11. Gillmann, A.G., Rall, T.W., Nies, A.S., Taylor, P. 1990. In: Goodman and Gillmann's The Pharmacological Basis Therapeutics. 8th ed. pp. 1485-1486. Pergamon, Maxwell House, New York, U.S.A.
12. Moyano, J.R., Arias-Blanco, M.J., Gines, J.M. Giordano, F. 1997. Solid-state characterization and dissolution characteristics of gliclazide-β-cyclodextrin inclusion complexes. Int. J. Pharm. 148: 211-217.
13. Özkan, Y., Atay, T., Dikmen, N., Işimer, A., Aboul-Enein, HY. 2000. Improvement of water solubility and in vitro dissolution rate of gliclazide by complexation with beta-cyclodextrin. Pharm. Acta Helv. 74: 365-370.
14. Aggarwal, S., Singh, P.N., Mishra, B. 2002. Studies on solubility and hypoglycemic activity of gliclazide beta-cyclodextrin-hydroxypropylmethyl cellulose complexes. Pharmazie. 57: 191-3.
15. Moyano, J.R., Arias-Blanco, M.J., Gines, J.M., Rabasco, A.M., Perez-Martinez, J.I., Mor, M., Giordano, F. 1997. Nuclear magnetic resonance investigations of the inclusion complexation of gliclazide with beta-cyclodextrin. J Pharm Sci. 86: 72-5.
16. Higuchi, T., Connors, K.A. 1965. Phase-solubility techniques. Adv. Anal. Chem. Instrum. 4: 117-212.
17. Otagiri, M., Imai, T., Hirayama, F., Uekama, K., Yamasaki, M. 1983. Inclusion complex formations of the anti-inflammatory drug flurbiprofen with cyclodextrins in aqueous solution and in solid state. Acta Pharm. Suec. 20: 11-20.
18. Redenti, E., Peveri, T., Zanol, M., Ventura, P., Gnappi, G., Montenero, A. 1996. A study on the differentiation between amorphous piroxicam: β-cyclodextrin complex and a mixture of the two amorphous components. Int. J. Pharm. 129: 289-294.
19. Winters, C.S., York, P., Timmins, P. 1997. Solid state examination of a gliclazide: beta-cyclodextrin complex. Eur. J. Pharm. Sci. 5: 209-214.