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Volumn 844, Issue 2, 2006, Pages 268-277
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Development and validation of a selective and robust LC-MS/MS method for high-throughput quantifying rizatriptan in small plasma samples: Application to a clinical pharmacokinetic study
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Author keywords
5 HT1B 1D receptor agonist; LC MS MS; Pharmacokinetics; Rizatriptan
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Indexed keywords
ACETIC ACID;
EXTRACTION;
IONIZATION;
LIQUID CHROMATOGRAPHY;
MASS SPECTROMETRY;
PHARMACOKINETICS;
AMMONIUM ACETATE-ACETIC ACID;
HUMAN PLASMA;
ION ELECTROSPRAY IONIZATION (ESI);
LIQUID-LIQUID EXTRACTION (LLE);
RIZATRIPTAN;
PROTEINS;
ACETIC ACID;
AMMONIUM ACETATE;
GRANISETRON;
RIZATRIPTAN;
SEROTONIN 1B AGONIST;
SEROTONIN 1D AGONIST;
ACCURACY;
ADULT;
AQUEOUS SOLUTION;
ARTICLE;
BLOOD SAMPLING;
CONTROLLED STUDY;
DRUG BLOOD LEVEL;
DRUG DETERMINATION;
DRUG ISOLATION;
DRUG MONITORING;
ELECTROSPRAY MASS SPECTROMETRY;
HIGH THROUGHPUT SCREENING;
HUMAN;
HUMAN EXPERIMENT;
LINEAR SYSTEM;
LIQUID CHROMATOGRAPHY;
LIQUID LIQUID EXTRACTION;
MASS SPECTROMETRY;
NORMAL HUMAN;
PRIORITY JOURNAL;
PROCESS DEVELOPMENT;
QUALITY CONTROL;
QUANTITATIVE ANALYSIS;
TANDEM MASS SPECTROMETRY;
VALIDATION STUDY;
ADULT;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
GRANISETRON;
HUMANS;
MALE;
MOLECULAR STRUCTURE;
REFERENCE STANDARDS;
REPRODUCIBILITY OF RESULTS;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
TANDEM MASS SPECTROMETRY;
TRIAZOLES;
TRYPTAMINES;
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EID: 33751318206
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2006.07.027 Document Type: Article |
Times cited : (25)
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References (13)
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