Hypertonic saline for the treatment of intracranial hypertension: Worth its salt

Critical Care Medicine

Volumn 34, Issue 12, 2006, Pages 3037-3039

  Levine, Joshua M ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Hypertonic saline; Intracranial hypertension; Intracranial pressure; Subarachnoid hemorrhage

Indexed keywords

HETASTARCH; MANNITOL; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; BRAIN ARTERY ANEURYSM; BRAIN BLOOD FLOW; BRAIN EDEMA; BRAIN PERFUSION; CLINICAL ARTICLE; CONTROLLED STUDY; EDITORIAL; HUMAN; INTRACRANIAL HYPERTENSION; INTRACRANIAL PRESSURE; NONHUMAN; PERFUSION PRESSURE; PRIORITY JOURNAL; SODIUM BLOOD LEVEL; SUBARACHNOID HEMORRHAGE; TREATMENT INDICATION; TREATMENT OUTCOME;

CEREBROVASCULAR CIRCULATION; HETASTARCH; HUMANS; INTRACRANIAL PRESSURE; MANNITOL; RANDOMIZED CONTROLLED TRIALS; SALINE SOLUTION, HYPERTONIC; SODIUM; SUBARACHNOID HEMORRHAGE;

EID: 33751309841     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.CCM.0000248527.85721.16     Document Type: Editorial

References (18)

1. Hartl R, Medary MB, Ruge M, et al: Hypertonic/hyperoncotic saline attenuates microcirculatory disturbances after traumatic brain injury. J Trauma 1997; 42(5 Suppl):S41-S47
2. Mazzoni MC, Borgstrom P, Arfors KE, et al: Dynamic fluid redistribution in hyperosmotic resuscitation of hypovolemic hemorrhage. Am J Physiol 1988; 255(3 Pt 2):H629-H637
3. Nakayama S, Kramer GC, Carlsen RC, et al: Infusion of very hypertonic saline to bled rats: Membrane potentials and fluid shifts. J Surg Res 1985; 38:180-186
4. Munar F, Ferrer AM, de Nadal M, et al: Cerebral hemodynamic effects of 7.2% hypertonic saline in patients with head injury and raised intracranial pressure. J Neurotrauma 2000; 17:41-51
5. Taylor G, Myers S, Kurth CD, et al: Hypertonic saline improves brain resuscitation in a pediatric model of head injury and hemorrhagic shock. J Pediatr Surg 1996; 31:65-70
6. Simma B, Burger R, Falk M, et al: A prospective, randomized, and controlled study of fluid management in children with severe head injury: Lactated Ringer's solution versus hypertonic saline. Crit Care Med 1998; 26:1265-1270
7. Peterson B, Khanna S, Fisher B, et al: Prolonged hypernatremia controls elevated intracranial pressure in head-injured pediatric patients. Crit Care Med 2000; 28:1136-1143
8. Fisher B, Thomas D, Peterson B: Hypertonic saline lowers raised intracranial pressure in children after head trauma. J Neurosurg Anesthesiol 1992; 4:4-10
9. Battison C, Andrews PJ, Graham C, et al: Randomized, controlled trial on the effect of a 20% mannitol solution and a 7.5% saline/6% dextran solution on increased intracranial pressure after brain injury. Crit Care Med 2005; 33:196-202
10. Vialet R, Albanese J, Thomachot L, et al: Isovolume hypertonic solutes (sodium chloride or mannitol) in the treatment of refractory posttraumatic intracranial hypertension: 2 mL/kg 7.5% saline is more effective than 2 mL/kg 20% mannitol. Crit Care Med 2003; 31:1683-1687
11. Suarez JI, Qureshi AI, Bhardwaj A, et al: Treatment of refractory intracranial hypertension with 23.4% saline. Crit Care Med 1998; 26:1118-1122
12. Schatzmann C, Heissler HE, Konig K, et al: Treatment of elevated intracranial pressure by infusions of 10% saline in severely head injured patients. Acta Neurochir Suppl 1998; 71:31-33
13. Horn P, Munch E, Vajkoczy P, et al: Hypertonic saline solution for control of elevated intracranial pressure in patients with exhausted response to mannitol and barbiturates. Neurol Res 1999; 21:758-764
14. Tseng MY, Al-Rawi PG, Pickard JD, et al: Effect of hypertonic saline on cerebral blood flow in poor-grade patients with subarachnoid hemorrhage. Stroke 2003; 34:1389-1396
15. Suarez JI, Qureshi AI, Parekh PD, et al: Administration of hypertonic (3%) sodium chloride/acetate in hyponatremic patients with symptomatic vasospasm following subarachnoid hemorrhage. J Neurosurg Anesthesiol 1999; 11:178-184
16. Bentsen G, Breivik H, Lundar T, et al: Predictable reduction of intracranial hypertension with hypertonic saline hydroxyethyl starch: A prospective clinical trial in critically ill patients with subarachnoid haemorrhage. Acta Anaesthesiol Scand 2004; 48:1089-1095
17. Bentsen G, Breivik H, Lundar T, et al: Hypertonic saline (7.2%) in 6% hydroxyethyl starch reduces intracranial pressure and improves hemodynamics in a placebo-controlled study involving stable patients with subarachnoid hemorrhage. Crit Care Med 2006; 34:2912-2917
18. Khanna S, Davis D, Peterson B, et al: Use of hypertonic saline in the treatment of severe refractory posttraumatic intracranial hypertension in pediatric traumatic brain injury. Crit Care Med 2000; 28:1144-1151