A polymorphism of C-to-T substitution at -31 IL1B is associated with the risk of advanced gastric adenocarcinoma in a Japanese population

Journal of Human Genetics

Volumn 51, Issue 11, 2006, Pages 927-933

  Ikehara, Sanae Kabata ^a,b   Ikehara, Yuzuru ^b   Matsuo, Keitaro ^b   Hirose, Kaoru ^b   Niwa, Toru ^b   Ito, Hidemi ^b   Ito, Seiji ^b   Kodera, Yasuhiro ^a   Yamamura, Yoshitaka ^b   Nakanishi, Hayao ^b   Tatematsu, Masae ^b   Tajima, Kazuo ^a,b  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b AICHI CANCER CENTER HOSPITAL   (Japan)

Author keywords

FAS; Gastric cancer; IL1B; NF B; Polymorphism

Indexed keywords

CYTOKINE; CYTOSINE; FAS ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1BETA; THYMIDINE;

ADULT; ADVANCED CANCER; AGED; ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; CANCER GROWTH; CANCER INCIDENCE; CANCER RISK; CANCER STAGING; CELL STIMULATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; GENE; GENE LINKAGE DISEQUILIBRIUM; GENE MUTATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; GENOTYPE; HUMAN; HUMAN EXPERIMENT; IL1B GENE; INFLAMMATION; JAPAN; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; POPULATION GENETICS; PROGNOSIS; PROTEIN FUNCTION; RISK ASSESSMENT; SIGNAL TRANSDUCTION; STOMACH ADENOCARCINOMA;

ADENOCARCINOMA; ADULT; AGED; ALLELES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INTERLEUKIN-1BETA; JAPAN; MALE; MIDDLE AGED; NF-KAPPA B; POLYMORPHISM, GENETIC; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS;

EID: 33751270603     PISSN: 14345161     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10038-006-0040-2     Document Type: Article

References (41)

1. Balkwill F, Mantovani A (2001) Inflammation and cancer: back to Virchow? Lancet 357:539-545
2. Bonizzi G, Karin M (2004) The two NF-kappaB activation pathways and their role in innate and adaptive immunity. Trends Immunol 25:280-288
3. Chang YW, Jang JY, Kim NH, Lee JW, Lee HJ, Jung WW, Dong SH, Kim HJ, Kim BH, Lee JI, Chang R (2005) Interleukin-1B (IL-1B) polymorphisms and gastric mucosal levels of IL-1beta cytokine in Korean patients with gastric cancer. Int J Cancer 114:465-471
4. Clevers H (2004) At the crossroads of inflammation and cancer. Cell 118:671-674
5. Cordon-Cardo C, Prives C (1999) At the crossroads of inflammation and tumorigenesis. J Exp Med 190:1367-1370
6. El-Omar EM, Carrington M, Chow WH, McColl KE, Bream JH, Young HA, Herrera J, Lissowska J, Yuan CC, Rothman N, Lanyon G, Martin M, Fraumeni JF, Jr. Rabkin CS (2000) Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature 404:398-402
7. El-Omar EM, Carrington M, Chow WH, McColl KE, Bream JH, Young HA, Herrera J, Lissowska J, Yuan CC, Rothman N, Lanyon G, Martin M, Fraumeni JF, Jr. Rabkin CS (2001) The role of interleukin-1 polymorphisms in the pathogenesis of gastric cancer. Nature 412:499
8. El-Omar EM, Rabkin CS, Gammon MD, Vaughan TL, Risch HA, Schoenberg JB, Stanford JL, Mayne ST, Goedert J, Blot WJ, Fraumeni JF, Jr. Chow WH (2003) Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms. Gastroenterology 124:1193-1201
9. Engelmark MT, Renkema KY, Gyllensten UB (2004) No evidence of the involvement of the Fas-670 promoter polymorphism in cervical cancer in situ. Int J Cancer 112:1084-1085
10. Greten FR, Karin M (2004) The IKK/NF-kappaB activation pathway - a target for prevention and treatment of cancer. Cancer Lett 206:193-199
11. Group HC (2001) Gastric cancer and Helicobacter pylori: a combined analysis of 12 case control studies nested within prospective cohorts. Gut 49:347-353
12. Hall SK, Perregaux DG, Gabel CA, Woodworth T, Durham LK, Huizinga TW, Breedveld FC, Seymour AB (2004) Correlation of polymorphic variation in the promoter region of the interleukin-1 beta gene with secretion of interleukin-1 beta protein. Arthritis Rheum 50:1976-1983
13. Hamajima N, Hirose K, Inoue M, Takezaki T, Kuroishi T, Tajima K (1995) Age-specific risk factors of breast cancer estimated by a case-control study in Japan. J Epidemiol 5:99-105
14. Hamajima N, Matsuo K, Saito T, Hirose K, Inoue M, Takezaki T, Kuroishi T, Tajima K (2001a) Gene-environment interactions and polymorphism studies of cancer risk in the hospital-based epidemiologic research program at Aichi Cancer Center II (HERPACC-II). Asian Pac J Cancer Prev 2:99-107
15. Hamajima N, Matsuo K, Saito T, Tajima K, Okuma K, Yamao K, Tominaga S (2001b) Interleukin 1 polymorphisms, lifestyle factors, and Helicobacter pylori infection. Jpn J Cancer Res 92:383-389
16. Huang QR, Morris D, Manolios N (1997) Identification and characterization of polymorphisms in the promoter region of the human Apo-1/Fas (CD95) gene. Mol Immunol 34:577-582
17. Hwang IR, Kodama T, Kikuchi S, Sakai K, Peterson LE, Graham DY, Yamaoka Y (2002) Effect of interleukin 1 polymorphisms on gastric mucosal interleukin 1beta production in Helicobacter pylori infection. Gastroenterology 123:1793-1803
18. Ikehara Y, Nishihara S, Kudo T, Hiraga T, Morozumi K, Hattori T, Narimatsu H (1998) The aberrant expression of Lewis a antigen in intestinal metaplastic cells of gastric mucosa is caused by augmentation of Lewis enzyme expression. Glycoconj J 15:799-807
19. Ikehara Y, Nishihara S, Yasutomi H, Kitamura T, Matsuo K, Shimizu N, Inada K, Kodera Y, Yamamura Y, Narimatsu H, Hamajima N, Tatematsu M (2001) Polymorphisms of two fucosyltransferase genes (Lewis and Secretor genes) involving type I Lewis antigens are associated with the presence of anti-Helicobacter pylori IgG antibody. Cancer Epidemiol Biomarkers Prev 10:971-977
20. Inoue M, Tajima K, Hirose K, Hamajima N, Takezaki T, Kuroishi T, Tominaga S (1997) Epidemiological features of first-visit outpatients in Japan: comparison with general population and variation by sex, age, and season. J Clin Epidemiol 50:69-77
21. Kanemitsu S, Ihara K, Saifddin A, Otsuka T, Takeuchi T, Nagayama J, Kuwano M, Hara T (2002) A functional polymorphism in fas (CD95/APO-1) gene promoter associated with systemic lupus erythematosus. J Rheumatol 29:1183-1188
22. Karin M, Cao Y, Greten FR, Li ZW (2002) NF-kappaB in cancer: from innocent bystander to major culprit. Nat Rev Cancer 2:301-310
23. Kimura R, Nishioka T, Soemantri A, Ishida T (2004) Cis-acting effect of the IL1B C-31T polymorphism on IL-1 beta mRNA expression. Genes Immun 5:572-575
24. Lai HC, Sytwu HK, Sun CA, Yu MH, Yu CP, Liu HS, Chang CC, Chu TY (2003) Single nucleotide polymorphism at Fas promoter is associated with cervical carcinogenesis. Int J Cancer 103:221-225
25. Lin A, Karin M (2003) NF-kappaB in cancer: a marked target. Semin Cancer Biol 13:107-114
26. Ma Y, Liu H, Tu-Rapp H, Thiesen HJ, Ibrahim SM, Cole SM, Pope RM (2004) Fas ligation on macrophages enhances IL-1R1-Toll-like receptor 4 signaling and promotes chronic inflammation. Nat Immunol 5:380-387
27. Machado JC, Figueiredo C, Canedo P, Pharoah P, Carvalho R, Nabais S, Castro Alves C, Campos ML, Van Doorn LJ, Caldas C, Seruca R, Carneiro F, Sobrinho-Simoes M (2003) A proinflammatory genetic profile increases the risk for chronic atrophic gastritis and gastric carcinoma. Gastroenterology 125:364-371
28. Osaki M, Kase S, Kodani I, Watanabe M, Adachi H, Ito H (2001) Expression of Fas and Fas ligand in human gastric adenomas and intestinal-type carcinomas: correlation with proliferation and apoptosis. Gastric Cancer 4:198-205
29. Palli D, Saieva C, Luzzi I, Masala G, Topa S, Sera F, Gemma S, Zanna I, D'Errico M, Zini E, Guidotti S, Valeri A, Fabbrucci P, Moretti R, Testai E, del Giudice G, Ottini L, Matullo G, Dogliotti E, Gomez-Miguel MJ (2005) Interleukin-1 gene polymorphisms and gastric cancer risk in a high-risk Italian population. Am J Gastroenterol 100:1941-1948
30. Peek RM Jr Blaser MJ (2002) Helicobacter pylori and gastrointestinal tract adenocarcinomas. Nat Rev Cancer 2:28-37
31. Sasaki N, Morisaki T, Hashizume K, Yao T, Tsuneyoshi M, Noshiro H, Nakamura K, Yamanaka T, Uchiyama A, Tanaka M, Katano M (2001) Nuclear factor-kappaB p65 (RelA) transcription factor is constitutively activated in human gastric carcinoma tissue. Clin Cancer Res 7:4136-4142
32. Senftleben U, Karin M (2002) The IKK/NF-kappa B pathway. Crit Care Med 30:S18-S26
33. Sibley K, Rollinson S, Allan JM, Smith AG, Law GR, Roddam PL, Skibola CF, Smith MT, Morgan GJ (2003) Functional FAS promoter polymorphisms are associated with increased risk of acute myeloid leukemia. Cancer Res 63:4327-4330
34. Sicinschi LA, Lopez-Carrillo L, Camargo MC, Correa P, Sierra RA, Henry RR, Chen J, Zabaleta J, Piazuelo MB, Schneider BG (2006) Gastric cancer risk in a Mexican population: role of Helicobacter pylori CagA positive infection and polymorphisms in interleukin-1 and -10 genes. Int J Cancer 118:649-657
35. Sun T, Miao X, Zhang X, Tan W, Xiong P, Lin D (2004) Polymorphisms of death pathway genes FAS and FASL in esophageal squamous-cell carcinoma. J Natl Cancer Inst 96:1030-1036
36. Uemura N, Okamoto S, Yamamoto S, Matsumura N, Yamaguchi S, Yamakido M, Taniyama K, Sasaki N, Schlemper RJ (2001) Helicobacter pylori infection and the development of gastric cancer. N Engl J Med 345:784-789
37. Vollmers HP, Dammrich J, Hensel F, Ribbert H, Meyer-Bahlburg A, Ufken-Gaul T, von Korff M, Muller-Hermelink HK (1997) Differential expression of apoptosis receptors on diffuse and intestinal type stomach carcinoma. Cancer 79:433-440
38. Xuan J, Deguchi R, Watanabe S, Ozawa H, Urano T, Ogawa Y, Fukuda R, Kijima H, Koga Y, Takagi A (2005) Relationship between IL-1beta gene polymorphism and gastric mucosal IL-1beta levels in patients with Helicobacter pylori infection. J Gastroenterol 40:796-801
39. Yang J, Hu Z, Xu Y, Shen J, Niu J, Hu X, Guo J, Wei Q, Wang X, Shen H (2004) Interleukin-1B gene promoter variants are associated with an increased risk of gastric cancer in a Chinese population. Cancer Lett 215:191-198
40. Yoshimura K, Hanaoka T, Ohnami S, Kohno T, Liu Y, Yoshida T, Sakamoto H, Tsugane S (2003) Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: data from population-based Japanese random samples. J Hum Genet 48:654-658
41. Zeng ZR, Hu PJ, Hu S, Pang RP, Chen MH, Ng M, Sung JJ (2003) Association of interleukin 1B gene polymorphism and gastric cancers in high and low prevalence regions in China. Gut 52:1684-1689