Respiratory and metabolic responses to early postnatal chronic intermittent hypoxia and sustained hypoxia in the developing rat

Pediatric Research

Volumn 60, Issue 6, 2006, Pages 680-686

  Reeves, Stephen R ^a   Gozal, David ^a,b  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF LOUISVILLE SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMBIENT AIR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; MALE; METABOLIC DISORDER; NEWBORN HYPOXIA; NONHUMAN; PLETHYSMOGRAPHY; POSTNATAL DEVELOPMENT; PREVALENCE; PRIORITY JOURNAL; RAT; RESPIRATORY FUNCTION;

ANIMALS; ANIMALS, NEWBORN; ANOXIA; BLOOD GAS ANALYSIS; MALE; PULMONARY VENTILATION; RATS; RATS, SPRAGUE-DAWLEY; RESPIRATORY SYSTEM; TIME FACTORS;

EID: 33751226890     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/01.pdr.0000246073.95911.18     Document Type: Article

References (35)

1. Powell FL, Milsom WK, Mitchell GS 1998 Time domains of the hypoxic ventilatory response. Respir Physiol 112:123-134
2. Lin J, Suguihara C, Huang J, Hehre D, Devia C, Bancalari E 1996 Effect of N-methyl-D-aspartate-receptor blockade on hypoxic ventilatory response in unanesthetized piglets. J Appl Physiol 80:1759-1763
3. Mizusawa A, Ogawa H, Kikuchi Y, Hida W, Kurosawa H, Okabe S, Takishima T, Shirato K 1994 In vivo release of glutamate in nucleus tractus solitarii of the rat during hypoxia. J Physiol 478:55-66
4. Soto-Arape I, Burton MD, Kazemi H 1995 Central amino acid neurotransmitters and the hypoxic ventilatory response. Am J Respir Crit Care Med 151:1113-1120
5. Ohtake PJ, Torres JE, Gozal YM, Graff GR, Gozal D 1998 NMDA receptors mediate peripheral chemoreceptor afferent input in the conscious rat. J Appl Physiol 84:853-861
6. Aaron EA, Powell FL 1993 Effect of chronic hypoxia on hypoxic ventilatory response in awake rats. J Appl Physiol 74:1635-1640
7. Mortola JP, Morgan CA, Virgona V 1986 Respiratory adaptation to chronic hypoxia in newborn rats. J Appl Physiol 61:1329-1336
8. Eden GJ, Hanson MA 1987 Effects of chronic hypoxia from birth on the ventilatory response to acute hypoxia in the newborn rat. J Physiol 392:11-19
9. Peyronnet J, Dalmaz Y, Ehrstrom M, Mamet J, Roux JC, Pequignot JM, Thoren HP, Lagercrantz H 2002 Long-lasting adverse effects of prenatal hypoxia on developing autonomic nervous system and cardiovascular parameters in rats. Pflugers Arch 443:858-865
10. Peyronnet J, Roux JC, Geloen A, Tang LQ, Pequignot JM, Lagercrantz H, Dalmaz Y 2000 Prenatal hypoxia impairs the postnatal development of neural and functional chemoafferent pathway in rat. J Physiol 524:525-537
11. Sladek M, Parker RA, Grogaard JB, Sundell HW 1993 Long-lasting effect of prolonged hypoxemia after birth on the immediate ventilatory response to changes in arterial partial pressure of oxygen in young lambs. Pediatr Res 34:821-828
12. Jackson A, Nurse C 1995 Plasticity in cultured carotid body chemoreceptors: environmental modulation of GAP-43 and neurofilament. J Neurobiol 26:485-496
13. Sterni LM, Bamford OS, Wasicko MJ, Carroll JL 1999 Chronic hypoxia abolished the postnatal increase in carotid body type I cell sensitivity to hypoxia. Am J Physiol 277:L645-L652
14. Bavis RW, Olson EB Jr, Vidruk EH, Fuller DD, Mitchell GS 2004 Developmental plasticity of the hypoxic ventilatory response in rats induced by neonatal hypoxia. J Physiol 557:645-660
15. Jones KL, Krous HF, Nadeau J, Blackbourne B, Zielke HR, Gozal D 2003 Vascular endothelial growth factor in the cerebrospinal fluid of infants who died of sudden infant death syndrome: evidence for antecedent hypoxia. Pediatrics 111:358-363
16. Gozal D, Lipton AJ, Jones KL 2002 Circulating vascular endothelial growth factor levels in patients with obstructive sleep apnea. Sleep 25:59-65
17. Reeves SR, Gozal E, Guo SZ, Sachleben LR Jr, Brittian KR, Lipton AJ, Gozal D 2003 Effect of long-term intermittent and sustained hypoxia on hypoxic ventilatory and metabolic responses in the adult rat. J Appl Physiol 95:1767-1774
18. Gozal D, Reeves SR, Row BW, Neville JJ, Guo SZ, Lipton AJ 2003 Respiratory effects of gestational intermittent hypoxia in the developing rat. Am J Respir Crit Care Med 167:1540-1547
19. Reeves SR, Gozal D 2005 Changes in ventilatory adaptations associated with long-term intermittent hypoxia across the age spectrum in the rat. Respir Physiol Neurobiol
20. Reeves SR, Gozal D 2006 Changes in ventilatory adaptations associated with long-term intermittent hypoxia across the age spectrum in the rat. Respir Physiol Neurobiol 150:135-143
21. Dwinell MR, Powell FL 1999 Chronic hypoxia enhances the phrenic nerve response to arterial chemoreceptor stimulation in anesthetized rats. J Appl Physiol 87:817-823
22. Gamboa A, Leon-Velarde F, Rivera-Ch M, Palacios JA, Pragnell TR, O'Connor DF, Robbins PA 2003 Selected contribution: acute and sustained ventilatory responses to hypoxia in high-altitude natives living at sea level. J Appl Physiol 94:1255-1262
23. Leon-Velarde F, Gamboa A, Rivera-Ch M, Palacios JA, Robbins PA 2003 Selected contribution: peripheral chemoreflex function in high-altitude natives and patients with chronic mountain sickness. J Appl Physiol 94:1269-1278
24. Alea OA, Czapla MA, Lasky JA, Simakajornboon N, Gozal E, Gozal D 2000 PDGF-beta receptor expression and ventilatory acclimatization to hypoxia in the rat. Am J Physiol Regul Integr Comp Physiol 279:R1625-R1633
25. Frappell PB, Mortola JP 1994 Hamsters vs. rats: metabolic and ventilatory response to development in chronic hypoxia. J Appl Physiol 77:2748-2752
26. Trippenbach T 1994 Ventilatory and metabolic effects of repeated hypoxia in conscious newborn rabbits. Am J Physiol 266:R1584-R1590
27. Peng YJ, Rennison J, Prabhakar NR 2004 Intermittent hypoxia augments carotid body and ventilatory response to hypoxia in neonatal rat pups. J Appl Physiol 97:2020-2025
28. Waters KA, Laferriere A, Paquette J, Goodyer C, Moss IR 1997 Curtailed respiration by repeated vs. isolated hypoxia in maturing piglets is unrelated to NTS ME or SP levels. J Appl Physiol 83:522-529
29. Waters KA, Tinworth KD 2001 Depression of ventilatory responses after daily, cyclic hypercapnic hypoxia in piglets. J Appl Physiol 90:1065-1073
30. Wickstrom HR, Berner J, Holgert H, Hokfelt T, Lagercrantz H 2004 Hypoxic response in newborn rat is attenuated by neurokinin-1 receptor blockade. Respir Physiol Neurobiol 140:19-31
31. Gozal D, Gozal E 1999 Episodic hypoxia enhances late hypoxic ventilation in developing rat: putative role of neuronal NO synthase. Am J Physiol 276:R17-R22
32. Peng YJ, Prabhakar NR 2004 Effect of two paradigms of chronic intermittent hypoxia on carotid body sensory activity. J Appl Physiol 96:1236-1242
33. Waters KA, Gozal D 2003 Responses to hypoxia during early development. Respir Physiol Neurobiol 136:115-129
34. McGuire M, Zhang Y, White DP, Ling L 2002 Effect of hypoxic episode number and severity on ventilatory long-term facilitation in awake rats. J Appl Physiol 93:2155-2161
35. Reeves SR, Guo SZ, Brittian KR, Row BW, Gozal D 2006 Anatomical changes in selected cardio-respiratory brainstem nuclei following early postnatal chronic intermittent hypoxia. Neurosci Lett 402:233-237