Selected contribution: Acute and sustained ventilatory responses to hypoxia in high-altitude natives living at sea level

Journal of Applied Physiology

Volumn 94, Issue 3, 2003, Pages 1255-1262

  Gamboa, Alfredo ^a   León Velarde, Fabiola ^a   Rivera Ch, Maria ^a   Palacios, Jose Antonio ^a   Pragnell, Timothy R ^b   O'Connor, David F ^b   Robbins, Peter A ^b  

^a UNIVERSIDAD PERUANA CAYETANO HEREDIA   (Peru)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Andean natives; Blunting; Chemoreflex; Human; Hypoxic ventilatory depression; Regulation of ventilation

Indexed keywords

CARBON DIOXIDE; OXYGEN;

ADULT; AGED; ALTITUDE; ARTICLE; CHEMORECEPTOR REFLEX; CONTROLLED STUDY; HUMAN; HUMAN EXPERIMENT; HYPOXIA; MALE; PRIORITY JOURNAL; RESPIRATION CONTROL; SEA LEVEL;

EID: 0037372408     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00856.2002     Document Type: Article

References (22)

1. Blesa MI, Lahiri S, Rashkind WJ, and Fishman AP. Normalization of the blunted ventilatory response to acute hypoxia in congenital cyanotic heart disease. N Engl J Med 296: 237-241, 1977.
2. Clement ID and Robbins PA. Dynamics of the ventilatory response to hypoxia in humans. Respir Physiol 92: 253-275, 1993.
3. Edelman NH, Lahiri S, Braudo L, Cherniack NS, and Fishman AP. The blunted ventilatory response to hypoxia in cyanotic congenital heart disease. N Engl J Med 282: 405-411, 1970.
4. 2 and hypoxia. J Appl Physiol 31: 586-592, 1971.
5. Howson MG, Khamnei S, McIntyre ME, O'Connor DF, and Robbins PA. A rapid computer-controlled binary gas-mixing system for studies in respiratory control (Abstract). J Physiol 394: 7P, 1987.
6. Lahiri S and Edelman NH. Peripheral chemoreflexes in the regulation of breathing of high altitude natives. Respir Physiol 6: 375-385, 1969.
7. Lahiri S, Kao FF, Velasquez T, Martinez C, and Pezzia W. Irreversible blunted respiratory sensitivity to hypoxia in high altitude natives. Respir Physiol 6: 360-374, 1969.
8. Lefrancois R, Gautier H, and Pasquis P. Ventilatory oxygen drive in acute and chronic hypoxia. Respir Physiol 4: 217-228, 1968.
9. Liang PJ, Bascom DA, and Robbins PA. Extended models of the ventilatory response to sustained isocapnic hypoxia in humans. J Appl Physiol 82: 667-677, 1997.
10. Milledge JS and Lahiri S. Respiratory control in lowlanders and sherpa highlanders at altitude. Respir Physiol 2: 310-322, 1967.
11. Mou XB, Howard LS, and Robbins PA. A protocol for determining the shape of the ventilatory response to hypoxia in humans. Respir Physiol 101: 139-143, 1995.
12. Robbins PA. Hypoxic ventilatory decline: site of action. J Appl Physiol 79: 373-374, 1995.
13. Robbins PA, Swanson GD, and Howson MG. A prediction-correction scheme for forcing alveolar gases along certain time courses. J Appl Physiol 52: 1353-1357, 1982.
14. 2 dissociation computations. J Appl Physiol 46: 599-602, 1979.
15. Severinghaus JW, Bainton CR, and Carcelen A. Respiratory insensitivity to hypoxia in chronically hypoxic man. Respir Physiol 1: 308-334, 1966.
16. Sørensen SC and Severinghaus JW. Irreversible respiratory insensitivity to acute hypoxia in man born at high altitude. J Appl Physiol 25: 217-220, 1968.
17. Sorensen SC and Severinghaus JW. Respiratory insensitivity to acute hypoxia persisting after correction of tetralogy of Fallot. J Appl Physiol 25: 221-223, 1968.
18. Vargas M, Leon-Velarde F, Monge-CC, Palacios JA, and Robbins PA. Similar hypoxic ventilatory responses in sea-level natives and high-altitude Andean natives living at sea level. J Appl Physiol 84: 1024-1029, 1998.
19. Velasquez T, Martinez C, Pezzia W, and Gallardo N. Ventilatory effects of oxygen in high altitude natives. Respir Physiol 5: 211-220, 1968.
20. 2 and hypoxia after sustained hypoxia in awake cats." J Appl Physiol 76: 2251-2252, 1994.
21. Weil JV, Byrne-Quinn E, Sodal IE, Filley GF, and Grover RF. Acquired attenuation of chemoreceptor function in chronically hypoxic man at high altitude. J Clin Invest 50: 186-195, 1971.
22. Zhang S and Robbins PA. Methodological and physiological variability within the ventilatory response to hypoxia in humans. J Appl Physiol 88: 1924-1932, 2000.