Effect of Normal Saline Infusion on the Diagnostic Utility of Base Deficit in Identifying Major Injury in Trauma Patients

Academic Emergency Medicine

Volumn 13, Issue 12, 2006, Pages 1269-1274

  Sinert, Richard ^a   Zehtabchi, Shahriar ^a   Bloem, Christina ^a   Lucchesi, Michael ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

base deficit; diagnosis; injury; normal saline; trauma

Indexed keywords

ACIDOSIS; ADULT; ARTICLE; BLOOD TRANSFUSION; CONFIDENCE INTERVAL; CONTROLLED STUDY; DATA ANALYSIS; DIAGNOSTIC TEST; DISEASE SEVERITY; FEMALE; HUMAN; INJURY; MAJOR CLINICAL STUDY; MALE; METABOLIC ACIDOSIS; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC;

ACIDOSIS; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; INJURY SEVERITY SCORE; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RESUSCITATION; ROC CURVE; SODIUM CHLORIDE; TRAUMA CENTERS; WOUNDS AND INJURIES;

EID: 33751224421     PISSN: 10696563     EISSN: None     Source Type: Journal    
DOI: 10.1197/j.aem.2006.07.027     Document Type: Article

References (32)

1. Davis J.W. The relationship of base deficit to lactate in porcine hemorrhagic shock and resuscitation. J Trauma 36 (1994) 168-172
2. Dunham C.M., Siegel J.H., Weireter L., et al. Oxygen debt and metabolic acidemia as quantitative predictors of mortality and the severity of the ischemic insult in hemorrhagic shock. Crit Care Med 19 (1991) 231-243
3. Aslar A.K., Kuzu M.A., Elhan A.H., Tanik A., and Hengirmen S. Admission lactate level and the APACHE II score are the most useful predictors of prognosis following torso trauma. Injury 35 (2004) 746-752
4. Kincaid E.H., Miller P.R., Meredith J.W., Rahman N., and Chang M.C. Elevated arterial base deficit in trauma patients: a marker of impaired oxygen utilization. J Am Coll Surg 187 (1998) 384-392
5. Davis J.W., Parks S.N., Kaups K.L., Gladen H.E., and O'Donnell-Nicol S. Admission base deficit predicts transfusion requirements and risk of complications. J Trauma 41 (1996) 769-774
6. Davis J.W., Shackford S.R., and Holbrook T.L. Base deficit as a sensitive indicator of compensated shock and tissue oxygen utilization. Surg Gynecol Obstet 173 (1991) 473-476
7. Davis J.W., Kaups K.L., and Parks S.N. Base deficit is superior to pH in evaluating clearance of acidosis after traumatic shock. J Trauma 44 (1998) 114-118
8. Rutherford E.J., Morris Jr. J.A., Reed G.W., and Hall K.S. Base deficit stratifies mortality and determines therapy. J Trauma 33 (1992) 417-423
9. Tremblay L.N., Feliciano D.V., and Rozycki G.S. Assessment of initial base deficit as a predictor of outcome: mechanism of injury does make a difference. Am Surg 68 (2002) 689-693
10. McGee S., Abernethy III W.B., and Simel D.L. The rational clinical examination. Is this patient hypovolemic?. JAMA 281 (1999) 1022-1029
11. Abou-Khalil B., Scalea T.M., Trooskin S.Z., Henry S.M., and Hitchcock R. Hemodynamic responses to shock in young trauma patients: need for invasive monitoring. Crit Care Med 22 (1994) 633-639
12. Scalea T.M., Simon H.M., Duncan A.O., et al. Geriatric blunt multiple trauma: improved survival with early invasive monitoring. J Trauma 30 (1990) 129-134
13. Mikulaschek A., Henry S.M., Donovan R., and Scalea T.M. Serum lactate is not predicted by anion gap or base excess after trauma resuscitation. J Trauma 40 (1996) 218-224
14. Martin M.J., Fitzsullivan E., Salim A., Brown C.V., Demetriades D., and Long W. Discordance between lactate and base deficit in the surgical intensive care unit: which one do you trust?. Am J Surg 191 (2006) 625-630
15. Jeng J.C., Jablonski K., Bridgeman A., and Jordan M.H. Serum lactate, not base deficit, rapidly predicts survival after major burns. Burns 28 (2002) 161-166
16. Skellett S., Mayer A., Durward A., Tibby S.M., and Murdoch I.A. Chasing the base deficit: Hyperchloraemic acidosis following 0.9% saline fluid resuscitation. Arch Dis Child 83 (2000) 514-516
17. Brill S.A., Stewart T.R., Brundage S.I., and Schreiber M.A. Base deficit does not predict mortality when secondary to hyperchloremic acidosis. Shock 17 (2002) 459-462
18. Waters J.H., and Bernstein C.A. Dilutional acidosis following hetastarch or albumin in healthy volunteers. Anesthesiology 93 (2000) 1184-1187
19. Mirza B.I., Sahani M., Leehey D.J., Patel S.B., Yang V.L., and Ing T.S. Saline-induced dilutional acidosis in a maintenance hemodialysis patient. Int J Artif Organs 22 (1999) 676-678
20. Oh M.S., Banerji M.A., and Carroll H.J. The mechanism of hyperchloremic acidosis during the recovery phase of diabetic ketoacidosis. Diabetes 30 (1981) 310-313
21. Liskaser F.J., Bellomo R., Hayhoe M., et al. Role of pump prime in the etiology and pathogenesis of cardiopulmonary bypass-associated acidosis. Anesthesiology 93 (2000) 1170-1173
22. Jaber B.L., and Madias N.E. Marked dilutional acidosis complicating management of right ventricular myocardial infarction. Am J Kidney Dis 30 (1997) 561-567
23. Mathes D.D., Morell R.C., and Rohr M.S. Dilutional acidosis: is it a real clinical entity?. Anesthesiology 86 (1997) 501-503
24. Waters J.H., Miller L.R., Clack S., and Kim J.V. Cause of metabolic acidosis in prolonged surgery. Crit Care Med 27 (1999) 2142-2146
25. Scheingraber S., Rehm M., Sehmisch C., and Finsterer U. Rapid saline infusion produces hyperchloremic acidosis in patients undergoing gynecologic surgery. Anesthesiology 90 (1999) 1265-1270
26. Association for the Advancement of Automotive Medicine. The Abbreviated Injury Scale, 1990 Revision (1990), Association for the Advancement of Automotive Medicine, Des Plaines, IL
27. Dunham C.M., Watson L.A., and Cooper C. Base deficit level indicating major injury is increased with ethanol. J Emerg Med 18 (2000) 165-171
28. Zehtabchi S., Baron B.J., Sinert R., et al. Ethanol and illicit drugs do not affect the diagnostic utility of base deficit and lactate in differentiating minor from major injury in trauma patients. Acad Emerg Med 11 (2004) 1014-1020
29. Baker S.P., O'Neill B., Haddon Jr. W., and Long W.B. The injury severity score: a method for describing patients with multiple injuries and evaluating emergency care. J Trauma 14 (1974) 187-196
30. Hanely J.A., and McNeil B.J. The meaning and the use of the area under a receiver operating characteristic (ROC) curve. Radiology 143 (1982) 29-36
31. Constable P.D. Hyperchloremic acidosis: the classic example of strong ion acidosis. Anesth Analg 96 (2003) 919
32. Stewart P.A. Modern quantitative acid-base chemistry. Can J Physiol Pharmacol 61 (1983) 1444-1461