Risk assessment and food allergy: the probabilistic model applied to allergens

Food and Chemical Toxicology

Volumn 45, Issue 1, 2007, Pages 49-54

  Spanjersberg, M Q I ^a   Kruizinga, A G ^a   Rennen, M A J ^a   Houben, G F ^a  

^a TNO   (Netherlands)

Author keywords

Food allergy; Modelling; Probabilistic; Risk assessment

Indexed keywords

FOOD ALLERGEN;

ALLERGIC REACTION; ARTICLE; FOOD ALLERGY; FOOD INTAKE; HAZELNUT; HEALTH HAZARD; MATHEMATICAL MODEL; PEANUT ALLERGY; PREVALENCE; PROBABILITY; RISK ASSESSMENT;

ALLERGENS; FOOD HYPERSENSITIVITY; HUMANS; MODELS, STATISTICAL; NUT HYPERSENSITIVITY; NUTS; RISK ASSESSMENT;

CORYLUS;

EID: 33751221001     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2006.07.018     Document Type: Article

References (15)

1. Bindslev-Jensen C., Briggs D., and Osterballe M. Can we determine a threshold level for allergenic foods by statistical analysis of published data in the literature?. Allergy 57 (2002) 741-746
2. Gibney M.J., and Van der Voet H. Introduction to the Monte Carlo project and the approach to the validation of probabilistic models of dietary exposure to selected food chemicals. Food Addit. Contam. 20 Suppl. 1 (2003) S1-S7
3. Houben, G., Penninks, A., Brussaard, T. Changes in practice of risk assessment: from possibility to probability. In: TNO International Food Allergy Forum 15-16 April 2002, The Netherlands.
4. Hourihane J.O.B., and Knulst A.C. Thresholds of allergenic proteins in foods. Toxicol. Appl. Pharmacol. 207 (2005) S152-S156
5. Hulshof K.F.A.M., Brussaard J.H., Kruizinga A.G., Telman J., and Lowik M.R.H. Socioeconomic status, dietary intake and 10y trends: the Dutch National food consumption survey. Eur. J. Clin. Nutr. 57 (2003) 128-137
6. Hupkens C. Prevalence of food allergies in Europe. TNO report, V99,1100. TNO. Zeist. 1999.
7. International Program on Chemical Safety (IPCS) 1999. WHO. Geneva.
8. Koppelman S.J., Knulst A.C., Koers W.J., Penninks A.H., Peppelman H., Vlooswijk R., Pigmans I., Van Duijn G., and Hessing M. Comparison of different immunochemical methods for the detection and quantification of hazelnut proteins in food products. J. Immun. Meth. 229 (1999) 107-120
9. Monte Carlo project. Practical guidelines document 3. Guidelines for the input of data into probabilistic models of exposure to food chemicals. 2003. Available from: .
10. Palisade Corporation. Guide to using @-RISK. 1997. Palisade Corporation.
11. Sampson H.A. Update on food allergy. J. Allergy Clin. Immunol. 113 (2004) 805-819
12. Slob W., and Pieters M.N. A probabilistic approach for deriving acceptable human intake limits and human health risks from toxicological studies: general framework. Risk Anal. 18 6 (1998) 787-798
13. Taylor S.L., Hefle S.L., Bindslev-Jensen C., Bock S.A., Burks A.W., Christie L., Hill D.J., Host A., Hourihane J.O.B., Lack G., Metcalfe D.D., Moneret-Vautrin D.A., Vadas P.A., Rance F., Skrypec D.J., Trautman T.A., Malmheden Yman I., and Zeiger R.S. Factors affecting the determination of threshold doses for allergenic foods: how much is too much?. J. Allergy Clin. Immunol. 109 (2002) 24-30
14. Taylor S.L., Hefle S.L., Bindslev-Jensen C., Atkins F.M., Andre C., Bruijnzeel-Koomen C., Burks A.W., Bush R.K., Ebisawa M., Eigenmann P.A., Host A., Hourihane J.O., Isolauri E., Hill D.J., Knulst A., Lack G., Sampson H.A., Moneret-Vautrin D.A., Rance F., Vadas P.A., Yunginger J.W., Zeiger R.S., Salminen J.W., Madsen C., and Abbott P. A consensus protocol for the determination of the threshold doses for allergenic foods: how much is too much?. Clin. Exp. Allergy 34 5 (2004) 689-695
15. Wensing M., et al. The range of minimum provoking doses in hazelnut-allergic patients as determined by double blinded placebo controlled food challenges. Clin. Exp. Allergy 32 12 (2002) 1757-1762