-
2
-
-
0032763885
-
Toluene diisocyanate colocalizes with tubulin on cilia of differentiated human airway epithelial cells
-
Lange R.W., et al. Toluene diisocyanate colocalizes with tubulin on cilia of differentiated human airway epithelial cells. Toxicol. Sci. 50 (1999) 64-71
-
(1999)
Toxicol. Sci.
, vol.50
, pp. 64-71
-
-
Lange, R.W.1
-
3
-
-
0032724702
-
Intracellular S-glutathionyl adducts in murine lung and human bronchoepithelial cells after exposure to diisocyanatotoluene
-
Lange R.W., et al. Intracellular S-glutathionyl adducts in murine lung and human bronchoepithelial cells after exposure to diisocyanatotoluene. Chem. Res. Toxicol. 12 (1999) 931-936
-
(1999)
Chem. Res. Toxicol.
, vol.12
, pp. 931-936
-
-
Lange, R.W.1
-
4
-
-
0034520174
-
Identification of human lung and skin proteins conjugated with hexamethylene diisocyanate in vitro and in vivo
-
Wisnewski A.V., et al. Identification of human lung and skin proteins conjugated with hexamethylene diisocyanate in vitro and in vivo. Am. J. Respir. Crit. Care Med. 162 (2000) 2330-2336
-
(2000)
Am. J. Respir. Crit. Care Med.
, vol.162
, pp. 2330-2336
-
-
Wisnewski, A.V.1
-
5
-
-
0030909675
-
Formation, solvolysis, and transcarbamoylation reactions of bis(S-glutathionyl) adducts of 2,4- and 2,6-diisocyanatotoluene
-
Day B.W., et al. Formation, solvolysis, and transcarbamoylation reactions of bis(S-glutathionyl) adducts of 2,4- and 2,6-diisocyanatotoluene. Chem. Res. Toxicol. 10 (1997) 424-431
-
(1997)
Chem. Res. Toxicol.
, vol.10
, pp. 424-431
-
-
Day, B.W.1
-
6
-
-
0032827632
-
Isocyanate-conjugated human lung epithelial cell proteins: a link between exposure and asthma
-
Wisnewski A.V., et al. Isocyanate-conjugated human lung epithelial cell proteins: a link between exposure and asthma. J. Allergy Clin. Immunol. 104 (1999) 341-347
-
(1999)
J. Allergy Clin. Immunol.
, vol.104
, pp. 341-347
-
-
Wisnewski, A.V.1
-
7
-
-
33751249782
-
Trimellitic anhydride-conjugated serum albumin activates rat alveolar macrophages in vitro
-
Valstar D.L., et al. Trimellitic anhydride-conjugated serum albumin activates rat alveolar macrophages in vitro. J. Occup. Med. Toxicol. 1 (2006) 13
-
(2006)
J. Occup. Med. Toxicol.
, vol.1
, pp. 13
-
-
Valstar, D.L.1
-
8
-
-
0036738889
-
Effects of hexamethylene diisocyanate exposure on human airway epithelial cells: in vitro cellular and molecular studies
-
Wisnewski A.V., et al. Effects of hexamethylene diisocyanate exposure on human airway epithelial cells: in vitro cellular and molecular studies. Environ. Health Perspect. 110 (2002) 901-907
-
(2002)
Environ. Health Perspect.
, vol.110
, pp. 901-907
-
-
Wisnewski, A.V.1
-
9
-
-
17144422061
-
Glutathione protects human airway proteins and epithelial cells from isocyanates
-
Wisnewski A.V., et al. Glutathione protects human airway proteins and epithelial cells from isocyanates. Clin. Exp. Allergy 35 (2005) 352-357
-
(2005)
Clin. Exp. Allergy
, vol.35
, pp. 352-357
-
-
Wisnewski, A.V.1
-
10
-
-
0023614039
-
The development of an animal model for TDI asthma
-
Karol M.H. The development of an animal model for TDI asthma. Bull. Eur. Physiopathol. Respir. 23 (1987) 571-576
-
(1987)
Bull. Eur. Physiopathol. Respir.
, vol.23
, pp. 571-576
-
-
Karol, M.H.1
-
11
-
-
33751219410
-
Modèles animaux
-
Bessot J.C., and Pauli G. (Eds), Margaux Orange
-
Pons F., et al. Modèles animaux. In: Bessot J.C., and Pauli G. (Eds). L'asthme Professionnel (1999), Margaux Orange 49-59
-
(1999)
L'asthme Professionnel
, pp. 49-59
-
-
Pons, F.1
-
12
-
-
0032930229
-
Long-term topical exposure to toluene diisocyanate in mice leads to antibody production and in vivo airway hyperresponsiveness three hours after intranasal challenge
-
Scheerens H., et al. Long-term topical exposure to toluene diisocyanate in mice leads to antibody production and in vivo airway hyperresponsiveness three hours after intranasal challenge. Am. J. Respir. Crit. Care Med. 159 (1999) 1074-1080
-
(1999)
Am. J. Respir. Crit. Care Med.
, vol.159
, pp. 1074-1080
-
-
Scheerens, H.1
-
13
-
-
0037006901
-
IgG and IgE antibody responses following exposure of Brown Norway rats to trimellitic anhydride: comparison of inhalation and topical exposure
-
Warbrick E.V., et al. IgG and IgE antibody responses following exposure of Brown Norway rats to trimellitic anhydride: comparison of inhalation and topical exposure. Toxicology 172 (2002) 157-168
-
(2002)
Toxicology
, vol.172
, pp. 157-168
-
-
Warbrick, E.V.1
-
14
-
-
14844293885
-
Exposure and immunological determinants in a murine model for toluene diisocyanate (TDI) asthma
-
Matheson J.M., et al. Exposure and immunological determinants in a murine model for toluene diisocyanate (TDI) asthma. Toxicol. Sci. 84 (2005) 88-98
-
(2005)
Toxicol. Sci.
, vol.84
, pp. 88-98
-
-
Matheson, J.M.1
-
15
-
-
0030989660
-
Immunohistochemical detection of toluene diisocyanate (TDI) adducts in pulmonary tissue of guinea-pigs following inhalation exposure
-
Karol M.H., et al. Immunohistochemical detection of toluene diisocyanate (TDI) adducts in pulmonary tissue of guinea-pigs following inhalation exposure. Inhalation Toxicol. 9 (1997) 63-83
-
(1997)
Inhalation Toxicol.
, vol.9
, pp. 63-83
-
-
Karol, M.H.1
-
16
-
-
0027332797
-
Toluene diisocyanate protein adducts in the bronchoalveolar lavage of guinea pigs exposed to vapors of the chemical
-
Jin R., et al. Toluene diisocyanate protein adducts in the bronchoalveolar lavage of guinea pigs exposed to vapors of the chemical. Chem. Res. Toxicol. 6 (1993) 906-912
-
(1993)
Chem. Res. Toxicol.
, vol.6
, pp. 906-912
-
-
Jin, R.1
-
17
-
-
0029978757
-
In vivo and in vitro reactions of toluene diisocyanate isomers with guinea pig hemoglobin
-
Day B.W., et al. In vivo and in vitro reactions of toluene diisocyanate isomers with guinea pig hemoglobin. Chem. Res. Toxicol. 9 (1996) 568-573
-
(1996)
Chem. Res. Toxicol.
, vol.9
, pp. 568-573
-
-
Day, B.W.1
-
18
-
-
0022340690
-
Airway hyperresponsiveness and inflammation induced by toluene diisocyanate in guinea pigs
-
Gordon T., et al. Airway hyperresponsiveness and inflammation induced by toluene diisocyanate in guinea pigs. Am. Rev. Respir. Dis. 132 (1985) 1106-1112
-
(1985)
Am. Rev. Respir. Dis.
, vol.132
, pp. 1106-1112
-
-
Gordon, T.1
-
19
-
-
0026490423
-
Bronchial hyperreactivity after inhalation of trimellitic anhydride dust in guinea pigs after intradermal sensitization to the free hapten
-
Hayes J.P., et al. Bronchial hyperreactivity after inhalation of trimellitic anhydride dust in guinea pigs after intradermal sensitization to the free hapten. Am. Rev. Respir. Dis. 146 (1992) 1311-1314
-
(1992)
Am. Rev. Respir. Dis.
, vol.146
, pp. 1311-1314
-
-
Hayes, J.P.1
-
20
-
-
0030794223
-
Bronchial hyperresponsiveness, epithelial damage, and airway eosinophilia after single and repeated allergen exposure in a rat model of anhydride-induced asthma
-
Cui Z.H., et al. Bronchial hyperresponsiveness, epithelial damage, and airway eosinophilia after single and repeated allergen exposure in a rat model of anhydride-induced asthma. Allergy 52 (1997) 739-746
-
(1997)
Allergy
, vol.52
, pp. 739-746
-
-
Cui, Z.H.1
-
21
-
-
0035884034
-
Trimellitic anhydride-induced eosinophilia in a mouse model of occupational asthma
-
Regal J.F., et al. Trimellitic anhydride-induced eosinophilia in a mouse model of occupational asthma. Toxicol. Appl. Pharmacol. 175 (2001) 234-242
-
(2001)
Toxicol. Appl. Pharmacol.
, vol.175
, pp. 234-242
-
-
Regal, J.F.1
-
22
-
-
0036252345
-
A novel mouse model of diisocyanate-induced asthma showing allergic-type inflammation in the lung after inhaled antigen challenge
-
Herrick C.A., et al. A novel mouse model of diisocyanate-induced asthma showing allergic-type inflammation in the lung after inhaled antigen challenge. J. Allergy Clin. Immunol. 109 (2002) 873-878
-
(2002)
J. Allergy Clin. Immunol.
, vol.109
, pp. 873-878
-
-
Herrick, C.A.1
-
23
-
-
4344601793
-
Respiratory response to toluene diisocyanate depends on prior frequency and concentration of dermal sensitization in mice
-
Vanoirbeek J.A., et al. Respiratory response to toluene diisocyanate depends on prior frequency and concentration of dermal sensitization in mice. Toxicol. Sci. 80 (2004) 310-321
-
(2004)
Toxicol. Sci.
, vol.80
, pp. 310-321
-
-
Vanoirbeek, J.A.1
-
24
-
-
14844312054
-
Immune mediators in a murine model for occupational asthma: studies with toluene diisocyanate
-
Matheson J.M., et al. Immune mediators in a murine model for occupational asthma: studies with toluene diisocyanate. Toxicol. Sci. 84 (2005) 99-109
-
(2005)
Toxicol. Sci.
, vol.84
, pp. 99-109
-
-
Matheson, J.M.1
-
25
-
-
28844463398
-
TDI can induce respiratory allergy with Th2-dominated response in mice
-
Ban M., et al. TDI can induce respiratory allergy with Th2-dominated response in mice. Toxicology 218 (2006) 39-47
-
(2006)
Toxicology
, vol.218
, pp. 39-47
-
-
Ban, M.1
-
26
-
-
0036708569
-
Interleukins 5 and 13 characterize immune responses to respiratory sensitizing acid anhydrides
-
Dearman R.J., et al. Interleukins 5 and 13 characterize immune responses to respiratory sensitizing acid anhydrides. J. Appl. Toxicol. 22 (2002) 317-325
-
(2002)
J. Appl. Toxicol.
, vol.22
, pp. 317-325
-
-
Dearman, R.J.1
-
27
-
-
0037728875
-
Differential roles for CD4 and CD8 T cells after diisocyanate sensitization: genetic control of TH2-induced lung inflammation
-
Herrick C.A., et al. Differential roles for CD4 and CD8 T cells after diisocyanate sensitization: genetic control of TH2-induced lung inflammation. J. Allergy Clin. Immunol. 111 (2003) 1087-1094
-
(2003)
J. Allergy Clin. Immunol.
, vol.111
, pp. 1087-1094
-
-
Herrick, C.A.1
-
28
-
-
0036787915
-
Role of tumor necrosis factor in toluene diisocyanate asthma
-
Matheson J.M., et al. Role of tumor necrosis factor in toluene diisocyanate asthma. Am. J. Respir. Cell Mol. Biol. 27 (2002) 396-405
-
(2002)
Am. J. Respir. Cell Mol. Biol.
, vol.27
, pp. 396-405
-
-
Matheson, J.M.1
-
29
-
-
25844527139
-
Prevention of IL-1 signaling attenuates airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma
-
Johnson V.J., et al. Prevention of IL-1 signaling attenuates airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma. J. Allergy Clin. Immunol. 116 (2005) 851-858
-
(2005)
J. Allergy Clin. Immunol.
, vol.116
, pp. 851-858
-
-
Johnson, V.J.1
-
30
-
-
0036533666
-
Contribution of vascular endothelial growth factor to airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma
-
Lee Y.C., et al. Contribution of vascular endothelial growth factor to airway hyperresponsiveness and inflammation in a murine model of toluene diisocyanate-induced asthma. J. Immunol. 168 (2002) 3595-3600
-
(2002)
J. Immunol.
, vol.168
, pp. 3595-3600
-
-
Lee, Y.C.1
-
31
-
-
0035217088
-
A murine model of toluene diisocyanate-induced asthma can be treated with matrix metalloproteinase inhibitor
-
Lee Y.C., et al. A murine model of toluene diisocyanate-induced asthma can be treated with matrix metalloproteinase inhibitor. J. Allergy Clin. Immunol. 108 (2001) 1021-1026
-
(2001)
J. Allergy Clin. Immunol.
, vol.108
, pp. 1021-1026
-
-
Lee, Y.C.1
-
32
-
-
0037204541
-
Computer systems for the prediction of toxicity: an update
-
Greene N. Computer systems for the prediction of toxicity: an update. Adv. Drug Deliv. Rev. 54 (2002) 417-431
-
(2002)
Adv. Drug Deliv. Rev.
, vol.54
, pp. 417-431
-
-
Greene, N.1
-
33
-
-
0042355457
-
In silico prediction of drug toxicity
-
Dearden J.C. In silico prediction of drug toxicity. J. Comput. Aided Mol. Des. 17 (2003) 119-127
-
(2003)
J. Comput. Aided Mol. Des.
, vol.17
, pp. 119-127
-
-
Dearden, J.C.1
-
34
-
-
0031442080
-
Structure-activity model of chemicals that cause human respiratory sensitization
-
Graham C., et al. Structure-activity model of chemicals that cause human respiratory sensitization. Regul. Toxicol. Pharmacol. 26 (1997) 296-306
-
(1997)
Regul. Toxicol. Pharmacol.
, vol.26
, pp. 296-306
-
-
Graham, C.1
-
35
-
-
18144424067
-
Development of an information-intensive structure-activity relationship model and its application to human respiratory chemical sensitizers
-
Cunningham A.R., et al. Development of an information-intensive structure-activity relationship model and its application to human respiratory chemical sensitizers. SAR QSAR Environ Res. 16 (2005) 273-285
-
(2005)
SAR QSAR Environ Res.
, vol.16
, pp. 273-285
-
-
Cunningham, A.R.1
-
36
-
-
15944387738
-
Relationship between chemical structure and the occupational asthma hazard of low molecular weight organic compounds
-
Jarvis J., et al. Relationship between chemical structure and the occupational asthma hazard of low molecular weight organic compounds. Occup. Environ. Med. 62 (2005) 243-250
-
(2005)
Occup. Environ. Med.
, vol.62
, pp. 243-250
-
-
Jarvis, J.1
|