Cdc2 tyrosine phosphorylation is not required for the S-phase DNA damage checkpoint in fission yeast

Cell Cycle

Volumn 5, Issue 21, 2006, Pages 2495-2500

  Kommajosyula, Naveen ^a   Rhind, Nicholas ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Cdc2; Cdc25; Fission yeast; Inter S checkpoint; S phase DNA damage checkpoint; Schizosaccharomyces pombe

Indexed keywords

ALKYLATING AGENT; CYCLIN DEPENDENT KINASE 1; PROTEIN TYROSINE PHOSPHATASE;

ARTICLE; CELL CULTURE; CELL CYCLE; CELL CYCLE S PHASE; CELL DIVISION; CELL TYPE; DNA DAMAGE; FLOW CYTOMETRY; GENOTYPE; METAZOON; PROTEIN DETERMINATION; PROTEIN PHOSPHORYLATION; WILD TYPE; YEAST;

METAZOA; SCHIZOSACCHAROMYCES POMBE;

EID: 33751209180     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.5.21.3423     Document Type: Article

References (30)

1. Bartek J, Lukas C, Lukas J. Checking on DNA damage in S phase. Nat Rev Mol Cell Biol 2004; 5:792-804.
2. Painter RB, Young BR. Radiosensitivity in ataxia-telangiectasia: A new explanation. Proc Nat Acad Sci USA 1980; 77:7315-7.
3. 2 progression, and results in apoptosis. Mol Biol Cell 1997; 8:1129-42.
4. Rhind N, Russell P. The Schizosaccharomyces pombe S-phase checkpoint differentiates between different types of DNA damage. Genetics 1998; 149:1729-37.
5. Myung K, Datta A, Kolodner RD. Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae. Cell 2001; 104:397-408.
6. Petrini JH. The Mre11 complex and ATM: Collaborating to navigate S phase. Current Opin Cell Biol 2000; 12:293-6.
7. Shirahige K, Hori Y, Shiraishi K, Yamashita M, Takahashi K, Obuse C, Tsurimoto T, Yoshikawa H. Regulation of DNA-replication origins during cell-cycle progression. Nature 1998; 395:618-21.
8. Costanzo V, Robertson K, Ying CY, Kim E, Avvedimento E, Gottesman M, Grieco D, Gautier J. Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage. Mol Cell 2000; 6:649-59.
9. Santocanale C, Diffley JF. A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication. Nature 1998; 395:615-8.
10. Larner JM, Lee H, Little RD, Dijkwel PA, Schildkraut CL, Hamlin JL. Radiation down-regulates replication origin activity throughout the S phase in mammalian cells. Nucleic Acids Res 1999; 27:803-9.
11. Falck J, Mailand N, Syljuasen RG, Bartek J, Lukas J. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 2001; 410:842-7.
12. Falck J, Petrini JH, Williams BR, Lukas J, Bartek J. The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways. Nat Genet 2002; 30:290-4.
13. Henry-Mowatt J, Jackson D, Masson JY, Johnson PA, Clements PM, Benson FE, Thompson LH, Takeda S, West SC, Caldecott KW. XRCC3 and Rad51 modulate replication fork progression on damaged vertebrate chromosomes. Mol Cell 2003; 11:1109-17.
14. Rhind N, Russell P. Checkpoints: It takes more than time to heal some wounds. Curr Biol 2000; 10:R908-R911.
15. Rhind N, Furnari B, Russell P. Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast. Genes and Development 1997; 11:504-11.
16. Rhind N, Russell P. Tyrosine phosphorylation of Cdc2 is required for the replication checkpoint in Schizosaccharomyces pombe. Mol Cell Biol 1998; 18:3782-7.
17. Kumar S, Huberman JA. On the slowing of S phase in response to DNA damage in fission yeast. J Biol Chem 2004; 279:43574-80.
18. Stern B, Nurse P. A quantitative model for the cdc2 control of S phase and mitosis in fission yeast. Trends Genet 1996; 12:345-50.
19. Christensen PU, Bentley NJ, Martinho RG, Nielsen O, Carr AM. Mik1 levels accumulate in S phase and may mediate an intrinsic link between S phase and mitosis. Proc Nat Acad Sci USA 2000; 97:2579-84.
20. Moreno S, Nurse P, Russell P. Regulation of mitosis by cyclic accumulation of p80cdc25 mitotic inducer in fission yeast. Nature 1990; 344:549-52.
21. Gould KL, Nurse P. Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis. Nature 1989; 342:39-45.
22. Lundgren K, Walworth N, Booher R, Dembski M, Kirschner M, Beach D. Mik1 and Wee1 cooperate in the inhibitory tyrosine phosphorylation of Cdc2. Cell 1991; 64:1111-22.
23. Gould KL, Moreno S, Tonks NK, Nurse P. Complementation of the mitotic activator, p80cdc25, by a human protein-tyrosine phosphatase. Science 1990; 250:1573-6.
24. Millar JBA, Lenaers G, Russell P. Pyp3 PTPase acts as a mitotic inducer in fission yeast. EMBO J 1992; 11:4933-41.
25. Carlson CR, Grallert B, Bernander R, Stokke T, Boye E. Measurement of nuclear DNA content in fission yeast by flow cytometry. Yeast 1997; 13:1329-35.
26. Lindsay HD, Griffiths DJ, Edwards RJ, Christensen PU, Murray JM, Osman F, Walworth N, Carr AM. S-phase-specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe. Genes Dev 1998; 12:382-95.
27. Enoch T, Nurse P. Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication. Cell 1990; 60:665-73.
28. Russell P, Nurse P. cdc25+ functions as an inducer in the mitotic control of fission yeast. Cell 1986; 45:145-53.
29. Chahwan C, Nakamura TM, Sivakumar S, Russell P, Rhind N. The fission yeast Rad32(Mre11)-Rad50-Nbs1 complex is required for the S-phase DNA damage checkpoint. Mol Cell Biol 2003; 23:6564-73.
30. Forsburg SL, Rhind N. Basic methods for fission yeast. Yeast 2006; 23:173-83.