Voltage-gated K+ channel block by catechol derivatives: Defining nonselective and selective pharmacophores

Journal of Pharmacology and Experimental Therapeutics

Volumn 319, Issue 2, 2006, Pages 758-764

  Salvador Recatala, Vicenta ^a   Kim, Yonjung ^a   Zaks Makhina, Elena ^a   Levitan, Edwin S ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 BICYCLO[2.2.1]HEPT 2 YL BENZENE 1,2 DIOL; CATECHOL DERIVATIVE; HYDROCARBON; TETRYLAMMONIUM; TYROSINE; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BRAIN CELL; CELL DEATH; CONTROLLED STUDY; DRUG INHIBITION; DRUG STRUCTURE; GENE MUTATION; HIGH THROUGHPUT SCREENING; INTESTINE CELL; NONHUMAN; PHARMACOPHORE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; BICYCLO COMPOUNDS; CATECHOLS; CHO CELLS; CRICETINAE; KV1.5 POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKERS; SHAB POTASSIUM CHANNELS; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAETHYLAMMONIUM COMPOUNDS;

EID: 33751188953     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.107607     Document Type: Article

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