Salicylate- and quinine-induced tinnitus and effects of memantine

Acta Oto-Laryngologica

Volumn 126, Issue SUPPL. 556, 2006, Pages 13-19

  Lobarinas, E ^a   Yang, G ^a   Sun, W ^a   Ding, D ^a   Mirza, N ^b   Dalby Brown, W ^b   Hilczmayer, E ^a   Fitzgerald, S ^a   Zhang, Liyan ^a   Salvi, Richard ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b NEUROSEARCH A S   (Denmark)

Author keywords

Auditory cortex; Behavior; Evoked potential; NMDA; Rats

Indexed keywords

MEMANTINE; QUININE; SALICYLATE SODIUM; WATER; ANALGESIC AGENT; CHOLINERGIC RECEPTOR BLOCKING AGENT; N METHYLASPARTIC ACID; NONSTEROID ANTIINFLAMMATORY AGENT; SALICYLIC ACID;

AMPLITUDE MODULATION; ANIMAL EXPERIMENT; ANIMAL MODEL; AUDITORY CORTEX; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; DRUG MEGADOSE; ELECTRIC POTENTIAL; EVOKED RESPONSE AUDIOMETRY; INFORMATION PROCESSING; LICKING; LOW DRUG DOSE; NONHUMAN; POLYDIPSIA; PRIORITY JOURNAL; RAT; SOUND; TINNITUS; ANIMAL; ARTICLE; CHEMICALLY INDUCED DISORDER; DOSE RESPONSE; EVOKED AUDITORY RESPONSE; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANALGESICS, NON-NARCOTIC; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; AUDITORY CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; EVOKED POTENTIALS, AUDITORY; MEMANTINE; N-METHYLASPARTATE; PARASYMPATHOLYTICS; QUININE; RATS; RATS, SPRAGUE-DAWLEY; SALICYLIC ACID; TINNITUS;

EID: 33751187322     PISSN: 00016489     EISSN: 16512553     Source Type: Journal    
DOI: 10.1080/03655230600895408     Document Type: Conference Paper

References (15)

1. Lockwood AH, Salvi RJ, Coad ML, Towsley ML, Wack DS, Murphy BW. The functional neuroanatomy of tinnitus: evidence for limbic system links and neural plasticity. Neurology 1998;50:114-20.
2. Kaltenbach JA. Neurophysiologic mechanisms of tinnitus. J Am Acad Audiol 2000;11:125-37.
3. Salvi RJ, Wang J, Ding D. Auditory plasticity and hyperactivity following cochlear damage. Hearing Res 2000;147:261-74.
4. Brozoski TJ, Bauer CA, Caspary DM. Elevated fusiform cell activity in the dorsal cochlear nucleus of chinchillas with psychophysical evidence of tinnitus. J Neurosci 2002;22:2383-90.
5. Milbrandt JC, Holder TM, Wilson MC, Salvi RJ, Caspary DM. GAD levels and muscimol binding in rat inferior colliculus following acoustic trauma. Hearing Res 2000;147:251-60.
6. Oestreicher E, Arnold W, Ehrenberger K, Felix D. Memantine suppresses the glutamatergic neurotransmission of mammalian inner hair cells. ORL J Otorhinolaryngol Relat Spec 1998;60:18-21.
7. Guitton MJ, Caston J, Ruel J, Johnson RM, Pujol R, Puel JL. Salicylate induces tinnitus through activation of cochlear NMDA receptors. J Neurosci 2003;23:3944-52.
8. Lobarinas E, Sun W, Cushing R, Salvi R. A novel behavioral paradigm for assessing tinnitus using schedule-induced polydipsia avoidance conditioning (SIP-AC). Hearing Res 2004;190:109-14.
9. Qiu C, Salvi R, Ding D, Burkard R. Inner hair cell loss leads to enhanced response amplitudes in auditory cortex of unanesthetized chinchillas: evidence for increased system gain. Hearing Res 2000;139:153-71.
10. Horikawa J, Ito S, Hosokawa Y, Homma T, Murata K. Tonotopic representation in the rat auditory cortex. Proc Jpn Acad Ser B 1988;64:260-3.
11. Jastreboff PJ, Brennan JF, Sasaki CT. Quinine-induced tinnitus in rats. Arch Otolaryngol Head Neck Surg 1991;117:1162-6.
12. Bauer CA, Brozoski TJ. Assessing tinnitus and prospective tinnitus therapeutics using a psychophysical animal model. J Assoc Res Otolaryngol 2001;2:54-64.
13. Areosa Sastre A, McShane R, Sherriff F. Memantine for dementia. Cochrane Database Syst Rev 2004:CD003154.
14. Ferris SH. Evaluation of memantine for the treatment of Alzheimer's disease. Expert Opin Pharmacother 2003;4:2305-13.
15. Cazals Y. Auditory sensori-neural alterations induced by salicylate. Prog Neurobiol 2000;62:583-631.