Thalidomide attenuates the development of fibrosis during post-infarction myocardial remodelling in rats

European Journal of Heart Failure

Volumn 8, Issue 8, 2006, Pages 790-796

  Yndestad, Arne ^a   Vinge, Leif Erik ^b   Bjørnerheim, Reidar ^c   Ueland, Thor ^a,b   Wang, Jacob E ^b   Frøland, Stig S ^a,b   Attramadal, Håvard ^b   Aukrust, Pål ^a,b   Øie, Erik ^b,d  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^d DIAKONHJEMMET HOSPITAL   (Norway)

Author keywords

Cytokine; Fibrosis; Heart failure; Inflammation; Intervention; Myocardial infarction

Indexed keywords

HYDROXYPROLINE; THALIDOMIDE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HEART FAILURE; HEART FUNCTION; HEART MUSCLE FIBROSIS; HEMODYNAMICS; IMMUNOMODULATION; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; RAT;

EID: 33751167419     PISSN: 13889842     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejheart.2006.02.007     Document Type: Article

References (28)

1. Aukrust P., Gullestad L., Ueland T., Damås J.K., and Yndestad A. Inflammatory and anti-inflammatory cytokines in chronic heart failure: potential therapeutic implications. Ann Med 37 (2005) 74-85
2. Mann D.L. Inflammatory mediators and the failing heart: past, present, and the foreseeable future. Circ Res 91 (2002) 988-998
3. Nian M., Lee P., Khaper N., and Liu P. Inflammatory cytokines and postmyocardial infarction remodeling. Circ Res 94 (2004) 1543-1553
4. Franks M.E., Macpherson G.R., and Figg W.D. Thalidomide. Lancet 363 (2004) 1802-1811
5. Gullestad L., Semb A.G., Holt E., et al. Effect of thalidomide in patients with chronic heart failure. Am Heart J 144 (2002) 847-850
6. Agoston I., Dibbs Z.I., Wang F., et al. Preclinical and clinical assessment of the safety and potential efficacy of thalidomide in heart failure. J Card Fail 8 (2002) 306-314
7. Davey P.P., and Ashrafian H. New therapies for heart failure: is thalidomide the answer?. Q J Med 93 (2000) 305-311
8. Oliver S.J., Moreira A., and Kaplan G. Immune stimulation in scleroderma patients treated with thalidomide. Clin Immunol 97 (2000) 109-120
9. Lee E.S., Kim Y.A., Kwon H.J., et al. Thalidomide upregulates macrophage inflammatory protein-1alpha in a herpes simplex virus-induced Behcet's disease-like animal model. Arch Dermatol Res 296 (2004) 175-181
10. Neben K., Moehler T., Kraemer A., et al. Response to thalidomide in progressive multiple myeloma is not mediated by inhibition of angiogenic cytokine secretion. Br J Haematol 115 (2001) 605-608
11. Yeh T.S., Ho Y.P., Huang S.F., et al. Thalidomide salvages lethal hepatic necroinflammation and accelerates recovery from cirrhosis in rats. J Hepatol 41 (2004) 606-612
12. Øie E., Vinge L.E., Tønnessen T., et al. Transient, isopeptide-specific induction of myocardial endothelin-1 mRNA in congestive heart failure in rats. Am J Physiol, Heart Circ Physiol 273 (1997) H1727-H1736
13. Bjørnerheim R., Grøgaard H.K., Kjekshus H., Attramadal H., and Smiseth O.A. High frame rate Doppler echocardiography in the rat: an evaluation of the method. Eur J Echocardiog 2 (2001) 78-87
14. Yndestad A., Holm A.M., Müller F., et al. Enhanced expression of inflammatory cytokines and activation markers in T-cells from patients with chronic heart failure. Cardiovasc Res 60 (2003) 141-146
15. Stegemann H., and Stalder K. Determination of hydroxyproline. Clin Chim Acta 18 (1967) 267-273
16. Sampaio E.P., Sarno E.N., Galilly R., Cohn Z.A., and Kaplan G. Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes. J Exp Med 173 (1991) 699-703
17. Corral L.G., and Kaplan G. Immunomodulation by thalidomide and thalidomide analogues. Ann Rheum Dis 58 Suppl 1 (1999) I107-I113
18. Teo S.K., Resztak K.E., Scheffler M.A., et al. Thalidomide in the treatment of leprosy. Microbes Infect 4 (2002) 1193-1202
19. Corral L.G., Haslett P.A., Muller G.W., et al. Differential cytokine modulation and T cell activation by two distinct classes of thalidomide analogues that are potent inhibitors of TNF-alpha. J Immunol 163 (1999) 380-386
20. Gullestad L., Ueland T., Fjeld J.G., et al. Effect of thalidomide on cardiac remodeling in chronic heart failure: results of a double-blind, placebo-controlled study. Circulation 112 (2005) 3408-3414
21. Brown R.D., Ambler S.K., Mitchell M.D., and Long C.S. The cardiac fibroblast: therapeutic target in myocardial remodeling and failure. Annu Rev Pharmacol Toxicol 45 (2005) 657-687
22. Pitt B., Zannad F., Remme W.J., et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 341 (1999) 709-717
23. Zannad F., Alla F., Dousset B., Perez A., and Pitt B. Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: insights from the randomized aldactone evaluation study (RALES). Rales Investigators. Circulation 102 (2000) 2700-2706
24. Nicoletti A., and Michel J.-B. Cardiac fibrosis and inflammation: interaction with hemodynamic and hormonal factors. Cardiovasc Res 41 (1999) 532-543
25. Miyata M., Tamura E., Motoki K., Nagata K., and Yamazoe Y. Thalidomide-induced suppression of embryo fibroblast proliferation requires CYP1A1-mediated activation. Drug Metab Dispos 31 (2003) 469-475
26. Chizzolini C., Rezzonico R., Ribbens C., et al. Inhibition of type I collagen production by dermal fibroblasts upon contact with activated T cells: different sensitivity to inhibition between systemic sclerosis and control fibroblasts. Arthritis Rheum 41 (1998) 2039-2047
27. Lienenluke B., Stojanovic T., Fiebig T., et al. Thalidomide impairment of trinitrobenzene sulphonic acid-induced colitis in the rat-role of endothelial cell-leukocyte interaction. Br J Pharmacol 133 (2001) 1414-1423
28. Park S.J., Kim H.S., Yang H.M., et al. Thalidomide as a potent inhibitor of neointimal hyperplasia after balloon injury in rat carotid artery. Arterioscler Thromb Vasc Biol 24 (2004) 885-891