Downregulation in the expression of the serine dehydratase in the rat liver during chronic metabolic acidosis

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 291, Issue 5, 2006, Pages

  López Flores, Inmaculada ^a   Peragón, Juan ^a   Valderrama, Raquel ^a   Esteban, Francisco J ^a   Luque, Francisco ^a   Peinado, M Ángeles ^a   Aranda, Fermín ^a   Lupiáñez, José A ^b   Barroso, Juan B ^a  

^a UNIVERSITY OF JAÉN   (Spain)

^b UNIVERSITY OF GRANADA   (Spain)

Author keywords

NH4Cl; Reverse transcriptase polymerase chain reaction; Serine catabolism

Indexed keywords

AMMONIUM CHLORIDE; MESSENGER RNA; SERINE DEHYDRATASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; IMMUNOHISTOCHEMISTRY; MALE; METABOLIC ACIDOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TISSUE DISTRIBUTION; WESTERN BLOTTING;

ACID-BASE EQUILIBRIUM; ACIDOSIS; ANIMALS; DOWN-REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYDROGEN-ION CONCENTRATION; KINETICS; L-SERINE DEHYDRATASE; LIVER; MALE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (ATP); RATS; RATS, WISTAR; RNA, MESSENGER; SERINE;

EID: 33751160840     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00095.2006     Document Type: Article

References (50)

1. Almond MK, Smith A, Cohen RD, Iles RA, and Flynn G. Substrate and pH effects on glutamine synthesis in rat liver. Consequences for acid-base regulation. Biochem J 278: 709-714, 1991.
2. Bailey JL, England BK, Long RC Jr, Weissman J, and Mitch WE. Experimental acidemia and muscle cell pH in chronic acidosis and renal failure. Am J Physiol Cell Physiol 269: C706-C712, 1995.
3. Barroso JB, Peragón J, Contreras-Jurado C, García-Salguero L, Corpas FJ, Esteban FJ, Peinado MA, De la Higuera M, and Lupiáñez JA. Impact of starvation-refeeding on kinetics and protein expression of trout liver NADPH-production systems. Am J Physiol Regul Integr Comp Physiol 274: R1578-R1587, 1998.
4. Boon L and Meijer AJ. Control by pH of urea synthesis in isolated rat hepatocytes. Eur J Biochem 172: 465-469, 1988.
5. 4. Am J Physiol Renal Fluid Electrolyte Physiol 250: F827-F833, 1986.
6. Botion LM, Brito MN, Brito NA, Brito SRC, Kettelhut IC, and Migliorini RH. Glucose contribution to in vivo synthesis of glyceride glycerol and fatty acids in rats adapted to high-protein, carbohydrate-free diet. Metabolism 47: 1217-1221, 1998.
7. Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254, 1976.
8. Bushinsky DA, Smith SB, Gavrilov KL, Gavrilov LF, Li J, and Levi-Setti R. Chronic acidosis-induced alteration in bone bicarbonate and phosphate. Am J Physiol Renal Physiol 285: F532-F539, 2003.
9. Cano N, Sturm JM, Meijer AJ, El-Mir MY, Novaretti R, Reynier JP, and Leverve XM. Effect of chronic renal failure with metabolic acidosis on alanine metabolism in isolated liver cells. Clin Nutr 23: 317-324, 2004.
10. Cassuto H, Olswang Y, Livoff AF, Nechushtan H, Hanson RW, and Reshef L. Involvement of HNF-1 in the regulation of phosphoenolpyruvate carboxykinase gene expression in the kidney. FEBS Lett 412: 597-602, 1997.
11. Cassuto H, Olswang Y, Heinemann S, Sabbagh K, Hanson RW, and Reshef L. The transcriptional regulation of phosphoenolpyruvate carboxykinase gene in the kidney requires the HNF-1 binding site of the gene. Gene 318: 177-184, 2003.
12. Chomczynski P and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987.
13. Conseil of European Communities. Aproximación de las disposiciones legales, reglamentarias y administrativas de los Estados miembros respecto a la protección de los animales utilizados para experimentación y otros fines científicos. Diario Oficial Comunidades Europeas 358: 1-8, 1986.
14. Curthoys NP and Gstraunthaler G. Mechanism of increased renal gene expression during metabolic acidosis. Am J Physiol Renal Physiol 281: F381-F390, 2001.
15. England BK, Greiber S, Mitch WE, Bowers BA, Herring J, McKean M, Ebb RG, Price SR, and Danner DJ. Rat muscle branched-chain ketoacid dehydrogenase activity and mRNAs increase with extracellular acidemia. Am J Physiol Cell Physiol 268: C1395-C1400, 1995.
16. Europe Conseil. Convenio europeo sobre protección de los animales vertebrados utilizados con fines experimentales y otros fines científicos. Boletín Oficial Estado, 256: 2187-2190, 1990.
17. Forrester RL, Wataji LJ, Silverman DA, and Pierre KJ. Enzymatic method for the determination of carbon dioxide in serum. Clin Chem 22: 243-247, 1976.
18. Frohlich J, Hoppe-Seyler G, Schollmeyer P, Maier KP, and Gerok W. Possible sites of interaction of acute renal failure with amino acid utilization for gluconeogenesis in isolated perfused rat liver. Eur J Clin Invest 7: 261-268, 1977.
19. Haas MJ and Pitot HC. Glucocorticoids stimulate CREB binding to a cyclic-AMP response element in the rat serine dehydratase gene. Arch Biochem Biophys 362: 317-324, 1999.
20. Hanson RW and Reshef L. Regulation of phosphoenolpyruvate carboxykinase (GTP) gene expression. Annu Rev Biochem 66: 581-611, 1997.
21. Haussinger D. Regulation of hepatic ammonia metabolism: the intracellular glutamine cycle. Adv Enzyme Regul 25: 159-180, 1986.
22. Hausssinger D, Sies H, and Gerok W. Functional hepatocyte heterogeneity in ammonia metabolism. The intercellular glutamine cycle. J Hepatol 1: 3-14, 1985.
23. Ishikawa E, Ninagawa T, and Suda M. Hormonal and dietary control of serine dehydratase in rat. J Biochem (Tokyo) 57: 506-513, 1965.
24. Jost JP, Khairallah EA, and Pitot HC. Studies on the induction and repression of enzymes in rat liver. V. Regulation of the rate of synthesis and degradation of serine dehydratase by dietary amino acids and glucose. J Biol Chem 243: 3057-3066, 1968.
25. Kanamoto R, Su Y, and Pitot HC. Effects of glucose, insulin and cAMP on transcription of the serine dehydratase gene in rat liver. Arch Biochem Biophys 288: 562-566, 1991.
26. Kashiwagura T, Ereckinska M, and Wilson DF. pH Dependence of hormonal regulation of gluconeogenesis and urea synthesis from glutamine in suspensions of hepatocytes. J Biol Chem 260: 407-414, 1985.
27. Klim RA, Albajar M, Hems R, and Williamson DH. Effects of chronic uraemia on the formation of glucose and urea plus ammonia from L-alanine, L-glutamine and L-serine in isolated rat hepatocytes. Clin Sci 70: 627-634, 1986.
28. Kraut JA and Kurtz I. Use of base in the treatment of severe acidemic status. Am J Kidney Dis 38: 703-727, 2001.
29. 4Cl ingestion in protein-deprived rats. Eur J Biochem 254: 428-432, 1998.
30. López-Flores I, Barroso JB, Valderrama R, Esteban FJ, Martínez-Lara E, Peinado MA, Ogawa H, Lupiáñez JA, and Peragón J. Serine dehydratase expression decreases in rat livers injured by chronic thioacetamide ingestion. Mol Cell Biochem 268: 33-43, 2005.
31. Masuda T, Ogawa H, Matsushima T, Kawamata S, Sasahara M, Kuroda K, Suzuki Y, Takata Y, Yamazaki M, Takusagawa F, and Pitot HC. Localization and hormonal control of serine dehydratase during metabolic acidosis differ markedly from those of phosphoenolpyruvate carboxykinase in rat kidney. Int J Biochem Cell Biol 35: 1234-1247, 2003.
32. Meisner H, Loose DS, and Hanson RW. Effects of hormones on transcription of the gene for cytosolic phosphoenolpyruvate carboxykinase (GTP) in rat kidney. Biochemistry 24: 421-425, 1985.
33. Ministerio de Agricultura, Pesca y Alimentación. Protección de los animales utilizados para experimentación y otros fines científicos. Boletín Oficial del Estado 67: 8509-8512, 1988.
34. Mitch WE, Medina R, Grieber S, May RC, England BK, Price SR, Bailey JL, and Goldberg AL. Metabolic acidosis stimulates muscle protein degradation by activating the adenosine triphosphate-dependent pathway involving ubiquitin and proteasomes. J Clin Invest 93: 2127-2133, 1994.
35. Ogawa H. Structure and function relationships of serine dehydratase from various sources. Trends Comp Biochem Physiol 6: 1-19, 2000.
36. Ogawa H, Fujioka M, Date T, Mueckler M, Su Y, and Pitot HC. Rat serine dehydratase gene codes for two species of mRNA of which only one is translated into serine dehydratase. J Biol Chem 265: 14407-14413, 1990.
37. Ogawa H, Fujioka M, Su Y, Kanamoto R, and Pitot HC. Nutritional regulation and tissue-specific expression of the serine dehydratase gene in rat. J Biol Chem 266: 20412-20417, 1991.
38. Ogawa H, Pitot HC, and Fujioka M. Diurnal variation of the serine dehydratase mRNA level in rat liver. Arch Biochem Biophys 308: 285-291, 1994.
39. Ogawa H, Kawamata S, Gomi T, Ansai Y, and Karaki Y. Laparatomy causes a transient induction of rat liver serine dehydratase mRNA. Arch Biochem Biophys 316: 844-850, 1995.
40. Ogawa H, Takusagawa F, Wakaki K, Kishi H, Eskandarian MR, Kobayashi M, Date T, Huh NH, and Pitot HC. Rat liver serine dehydratase. Bacterial expression and two folding domains as revealed by limited proteolysis. J Biol Chem 274: 12855-12860, 1999.
41. Pitot HC and Peraino C. Studies on the induction and repression of enzymes in rat liver. I Induction of threonine dehydratase and ornithine transaminase by oral intubation of casein hydrolysate. J Biol Chem 239: 1783-1788, 1964.
42. Rodríguez-Bayona B and Peragón J. Stimulation of rat-liver branched-chain α-keto acid dehydrogenase activity by chronic metabolic acidosis. Int J Biochem Cell Biol 30: 529-534, 1998.
43. Safránek R, Holecek M, Kadlcíková J, Sprongl L, Mislanová C, Kukan M, and Chládek J. Effect of acute acidosis on protein and amino acid metabolism in rats. Clin Nutr 22: 437-443, 2003.
44. Sandoval IV and Sols A. Gluconeogenesis from serine by the serine-dehydratase-dependent pathway in rat liver. Eur J Biochem 43: 609-616, 1974.
45. Shu SY, Ju G, and Fan LZ. The glucose-oxidase-DAB-nickel method in peroxidase histochemistry of the nevous system. Neurosci Lett 85: 169-171, 1988.
46. Snell K. Enzymes of serine metabolism in normal, developing and neoplastic rat tissues. Adv Enzyme Regul 22: 325-400, 1984.
47. Su Y, Kanamoto R, Miller DA, Ogawa H, and Pitot HC. Regulation of the expression of the serine dehydratase gene in the kidney and liver of the rat. Biochem Biophys Res Commun 170: 892-899, 1990.
48. Sugimoto S, Mitaka T, Ikeda S, Harada K, Ikai I, Yamaoka Y, and Mochizuki Y. Morphological changes induced by extracellular matrix are correlated with maturation of rat small hepatocytes. J Cell Biochem 87: 16-28, 2002.
49. Welbourne TC. Glucocorticoid and acid-base homeostasis. Effect of glutamine metabolism and transport. Am J Kidney Dis 65: 293-297, 1989.
50. Welbourne TC, Phromphetcharat V, Givens G, and Joshi S. Regulation of interorganal glutamine flow in metabolic acidosis. Am J Physiol Endocrinol Metab 250: E457-E463, 1986.