The function of proprioceptors in bone organization: A possible explanation for neurogenic heterotopic ossification in patients with neurological damage

Medical Hypotheses

Volumn 68, Issue 1, 2007, Pages 67-73

  da Paz, Aloysio Campos ^a   Carod Artal, Francisco J ^a   Kalil, Ricardo K ^a  

^a SARAH NETWORK OF REHABILITATION HOSPITALS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ACCELERATION; ARTICLE; BONE MATURATION; BONE TISSUE; BRAIN INJURY; CENTRAL NERVOUS SYSTEM DISEASE; COORDINATION DISORDER; DECELERATION; GAIT; HETEROTOPIC OSSIFICATION; HUMAN; LIGAMENT DISEASE; LIMB; MUSCLE CONTRACTION; NERVE ENDING; NERVE TRACT; PRIORITY JOURNAL; PROPRIOCEPTION; REHABILITATION CENTER; RELAPSE; SPINAL CORD INJURY; STIMULUS RESPONSE; TISSUE DIFFERENTIATION;

EID: 33751120192     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2006.06.035     Document Type: Article

References (33)

1. Roesler H. The history of some fundamental concepts in bone biomechanics. J Biomech 20 (1987) 1025-1034
2. Siffert R., Luo G., Cowin S., and Kaufman J.J. Dynamic relationships of trabecular bone density, architecture, and strength in a computational model osteopenia. Bone 18 (1996) 197-206
3. Kurz H., Sandau K., and Christ B. On the bifurcation of blood vessels - Wilhelm Roux's doctoral thesis (Jena 1878) - a seminal work for biophysical modeling in developmental biology. Anat Anz 179 (1997) 33-36
4. Wolf J. The law of bone remodeling (1986), Springer, Berlin
5. Trueta J. Studies of the development and decay of the human frame (1968), William Heinemann, London
6. Huiskes R. If bone is the answer, what is the question?. J Anat 197 (2000) 145-165
7. van Kuijk A., Geurts A.C., and van Kruppevelt H.J.M. Neurogenic heterotopic ossification in spinal cord injury. Spinal cord 40 (2002) 313-326
8. Chalmers J., Gray D.H., and Rush J. Observations on the induction of bone in soft tissues. J Bone J Surg Br 57 (1975) 36-45
9. Izumi K. Study of ectopic bone formation in experimental spinal cord injured rabbits. Paraplegia 21 (1983) 351-363
10. Michelsson J.E., Granroth G., and Anderson L.C. Myositis ossificans following forcible manipulation of the leg: A rabbit model for the study of heterotopic bone formation. J Bone Joint Surg Am 62 (1980) 811-815
11. Otlinowski J. Heterotopic induction of osteogenesis in course of neural injury. Pat Pol 44 (1993) 133-168
12. Scherbel U., Riess P., Khurana J., Born C., and DeLong W. Expression of bone morphogenetic proteins in rats with and without brain injury and tibia fracture. Orthop J (The University of Pennsylvania) 14 (2001) 85-89
13. Freeman M., and Wyke B.D. The innervation of the knee joint. An anatomical and histological study in the cat. J Anat 101 (1967) 505-532
14. Nieuwenhuys R., Nieuwenhuys R., and Voogd J. Human central nervous system. 3rd ed. (1996), Springer, Berlin
15. Brodal P. The central nervous system. 3rd ed. (2003), Oxford University Press, Oxford
16. Giles L.G., and Harvey A.R. Immunohistochemical demonstration of nociceptors in the capsule and synovial folds of human zygapophyseal joints. Br J Rheumatol 26 (1987) 362-364
17. Celis J.E. Cell biology. 2nd ed. (1998), Academic Press, San Diego
18. McCarthy E.F., and Sundaram M. Heterotopic ossification: a review. Skeletal Radiol 34 (2005) 609-619
19. Wittenberg R.H., Peschke U., and Botel U. Heterotopic ossification after spinal cord injury; epidemiology and risk factors. J Bone Joint Surg Br 74 (1992) 215-218
20. Dejerine A., and Ceillier M.A. Para-ostéo-arthropathies dês paraplégiques par lésion médullaire: Ètude clinique et radiographique. Ann Méd 5 (1918) 497-535
21. Major P., Resnick D., and Greenway G. Heterotopic ossification in paraplegia: a possible disturbance of the paravertebral venous plexus. Radiology 136 (1980) 797-799
22. High W.B. Effects of orally administered prostaglandin E2 on cortical bone turn over in adults dogs; a histomorphometric study. Bone 8 (1987) 363-373
23. Daud O., Sett P., Burr R.G., and Silver J.R. The relationship of heterotopic ossification to passive movements in paraplegic patients. Disab Rehab 15 (1993) 114-118
24. Izumi K. Study of ectopic bone formation in experimental spinal cord injured rabbits. Paraplegia 21 (1983) 351-363
25. Michelsson J.E., and Rauschning W. Pathogenesis of experimental heterotopic bone formation following temporary forcible exercising of immobilized limbs. Clin Orthop 176 (1983) 265-272
26. Morley J., Marsh S., Drakoulakis E., Pape H.C., and Giannoudis P.V. Does traumatic brain injury result in accelerated fracture healing?. Injury 36 (2005) 363-368
27. Andermahr J., Elsner A., Brings A.E., Hensler T., Gerbershagen H., and Jubel A. Reduced collagen degradation in polytraumas with traumatic brain injury causes enhanced osteogenesis. J Neurotrauma 23 (2006) 708-720
28. Boulet M., and Marier J.R. Precipitation of calcium phosphates from solution at near physiological concentration. Arch Biochem 93 (1961) 157
29. Newman R.J., Stone M.H., and Mukherjee S.K. Accelerated fracture union in association with severe head injury. Injury 18 (1987) 241-246
30. Creutzfeldt O.D. Cortex cerebri (1995), Oxford Science, Oxford
31. Duthie R.B., and Barker A.N. The histochemistry of the preosseous stage of bone repair studied by autoradiography. J Bone Joint Surg Br 37 (1955) 691-710
32. Lodish H. Molecular cell biology. 5th ed. (2004), WH Freeman, New York
33. Alberts B., Johnson A., Lewis J., Raff M., Robert K., and Walter R. The molecular cell biology. 4th ed. (2002), Garland, London