Activation of bombesin receptor subtype-3 stimulates adhesion of lung cancer cells

Lung Cancer

Volumn 54, Issue 2, 2006, Pages 143-148

  Hou, Xinghua ^a   Wei, Li ^a   Harada, Akihiro ^a   Tatamoto, Kazuhiko ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

Adhesion; Bombesin receptor subtype 3; Laminin; NCI N417 cell; Small cell lung cancer cell

Indexed keywords

ANTIBODY; BETA1 INTEGRIN; BETA1 INTEGRIN ANTIBODY; BOMBESIN RECEPTOR; BOMBESIN RECEPTOR SUBTYPE 3; BOMBESIN RECEPTOR SUBTYPE 3 AGONIST; BOMBESIN[6-13][6 DEXTRO PHENYLALANINE 11 BETA ALANINE 13 PHENYLALANINE 14 NORLEUCINE]; HORMONE RECEPTOR STIMULATING AGENT; LAMININ; UNCLASSIFIED DRUG; VINCULIN;

ANTIGEN ANTIBODY REACTION; ARTICLE; CANCER CELL; CANCER INVASION; CELL ADHESION; CELL CULTURE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOREACTIVITY; LUNG SMALL CELL CANCER; METASTASIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ANTIGENS, CD29; BOMBESIN; CARCINOMA, SMALL CELL; CELL ADHESION; CELL LINE, TUMOR; FOCAL ADHESIONS; HUMANS; LAMININ; LUNG NEOPLASMS; OLIGOPEPTIDES; PEPTIDE FRAGMENTS; RECEPTORS, BOMBESIN; SOMATOSTATIN; VINCULIN;

EID: 33751101651     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2006.08.005     Document Type: Article

References (18)

1. Gorbulev V., Akhundova A., Buchner H., and Fahrenholz F. Molecular cloning of a new bombesin receptor subtype expressed in uterus during pregnancy. Eur J Biochem 208 (1992) 405-410
2. Fathi Z., Corjay M.H., Shapira H., Wada E., Benya R., Jensen R., et al. BRS-3: a novel bombesin receptor subtype selectively expressed in testis and lung carcinoma cells. J Biol Chem 268 (1993) 5979-5984
3. Ohki-Hamazaki H., Watase K., Yamamoto K., Ogura H., Yamano M., Yamada K., et al. Mice lacking bombesin receptor subtype-3 develop metabolic defects and obesity. Nature 390 (1997) 165-169
4. Mantey S.A., Weber H.C., Sainz E., Akeson M., Ryan R.R., Pradhan T.K., et al. Discovery of a high affinity radioligand for the human orphan receptor, bombesin receptor subtype 3, which demonstrates that it has a unique pharmacology compared with other mammalian bombesin receptors. J. Biol. Chem. 272 (1997) 26062-26071
5. Ryan R.R., Weber H.C., Mantey S.A., Hou W., Hilburger M.E., Pradhan T.K., et al. Pharmacology and intracellular signaling mechanisms of the native human orphan receptor BRS-3 in lung cancer cells. J. Pharmacol. Exp. Ther. 287 (1998) 366-380
6. Fridman R., Giaccone G., Kanemoto T., Martin G.R., Gazdar A.F., and Mulshine J.L. Reconstituted basement membrane (matrigel) and laminin can enhance the tumorigenicity and the drug resistance of small cell lung cancer cell lines. Proc. Natl. Acad. Sci. USA 87 (1990) 6698-6702
7. Giaccone G., Broers J., Jensen S., Fridman R.I., Linnoila R., and Gazdar A.F. Increased expression of differentiation markers can accompany laminin-induced attachment of small cell lung cancer cells. Br. J. Cancer 66 (1992) 488-495
8. 1 integrin-mediated adhesion and neurite-like outgrowth and inhibits proliferation of small cell lung carcinoma cells. Cancer Res 60 (2000) 457-466
9. Martin G.R., and Timpl R. Laminin and other basement membrane components. Annu Rev Cell Biol 3 (1987) 57-85
10. Quigley R.L., Shafer S.H., and Williams C.L. Regulation of integrin-mediated adhesion by muscarinic acetylcholine receptors and protein kinase C in small cell lung carcinoma. Chest 114 (1998) 839-846
11. Enoki T., Miwa S., Sakamoto A., Minowa T., Komuro T., Kobayashi S., et al. Long-lasting activation of cation current by low concentration of endothelin-1 in mouse fibroblasts and smooth muscle cells of rabbit aorta. Br J Pharmacol 115 (1995) 479-485
12. Ryan R.R., Weber H.C., Hou W., Sainz E., Mantey S.A., Battey J.F., et al. Ability of various bombesin receptor agonists and antagonists to alter intracellular signaling of the human orphan receptor BRS-3. J Biol Chem 273 (1998) 13613-13624
13. Feldman L.E., Shin K.C., and Natale R.B. Todd III RF. Beta-1 integrin expression on human small cell lung cancer cells. Cancer Res 51 (1991) 1065-1070
14. Pellegrini R., Martignone S., Menard S., and Colnaghi M.I. Laminin receptor expression and function in small-cell lung carcinoma. Int J Cancer Suppl 8 (1994) 116-120
15. Clark E.A., and Brugge J.S. Integrins and signal transduction pathways: the road taken. Science 268 (1995) 233-239
16. Hynes R.O. Integrins: versatility, modulation, and signaling in cell adhesion. Cell 69 (1992) 11-25
17. Gumbiner B.M. Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell 84 (1996) 345-357
18. Minna J.D., Higgin G.A., and Glatstein E.J. In: DeVita V.T., Hellman S., and Rosenberg S. (Eds). Principles and practice of oncology (1985), Lippincott, Philadelphia 507-599