-
1
-
-
0033036759
-
Inhibitors of protein kinases: CGP 41251, a protein kinase inhibitor with potential as an anticancer agent
-
Fabbro D, Buchdunger E, Wood J et al. Inhibitors of protein kinases: CGP 41251, a protein kinase inhibitor with potential as an anticancer agent. Pharmacol Ther 1999; 82: 293-301.
-
(1999)
Pharmacol Ther
, vol.82
, pp. 293-301
-
-
Fabbro, D.1
Buchdunger, E.2
Wood, J.3
-
2
-
-
0035793623
-
Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants
-
Gille H, Kowalski J, Li B et al. Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants. J Biol Chem 2001; 276: 3222-30.
-
(2001)
J Biol Chem
, vol.276
, pp. 3222-3230
-
-
Gille, H.1
Kowalski, J.2
Li, B.3
-
3
-
-
0037703184
-
Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1
-
Autiero M, Waltenberger J, Communi D et al. Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1. Nat Med 2003; 9: 936-43.
-
(2003)
Nat Med
, vol.9
, pp. 936-943
-
-
Autiero, M.1
Waltenberger, J.2
Communi, D.3
-
4
-
-
0036306121
-
Vascular growth factors and lymphangiogenesis
-
Jussila L, Alitalo K. Vascular growth factors and lymphangiogenesis. Physiol Rev 2002; 82: 673-700.
-
(2002)
Physiol Rev
, vol.82
, pp. 673-700
-
-
Jussila, L.1
Alitalo, K.2
-
5
-
-
25444525461
-
Opinion: Emerging mechanisms of tumour lymphangiogenesis and lymphatic metastasis
-
Cao Y. Opinion: emerging mechanisms of tumour lymphangiogenesis and lymphatic metastasis. Nat Rev Cancer 2005; 5: 735-43.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 735-743
-
-
Cao, Y.1
-
6
-
-
7444224685
-
Integrating the anti-VEGF-A humanized monoclonal antibody bevacizumab with chemotherapy in advanced colorectal cancer
-
Hurwitz H. Integrating the anti-VEGF-A humanized monoclonal antibody bevacizumab with chemotherapy in advanced colorectal cancer. Clin Colorectal Cancer 2004; 4 (Suppl. 2): S62-8.
-
(2004)
Clin Colorectal Cancer
, vol.4
, Issue.SUPPL. 2
-
-
Hurwitz, H.1
-
7
-
-
3042538425
-
Anti-vascular endothelial growth factor monoclonals in non-small cell lung cancer
-
Sandler AB, Johnson DH, Herbst RS. Anti-vascular endothelial growth factor monoclonals in non-small cell lung cancer. Clin Cancer Res 2004; 10 (12 Pt 2): 4258s-62s.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.12 PART 2
-
-
Sandler, A.B.1
Johnson, D.H.2
Herbst, R.S.3
-
8
-
-
31544436073
-
A physiologic imaging pilot study of breast cancer treated with AZD2171
-
Miller KD, Miller M, Mehrotra S et al. A physiologic imaging pilot study of breast cancer treated with AZD2171. Clin Cancer Res 2006; 12: 281-8.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 281-288
-
-
Miller, K.D.1
Miller, M.2
Mehrotra, S.3
-
9
-
-
23044510046
-
Safety and pharmacokinetics of the dual action Raf kinase and vascular endothelial growth factor receptor inhibitor, BAY 43-9006, in patients with advanced, refractory solid tumors
-
Clark JW, Eder JP, Ryan D, Lathia C, Lenz HJ. Safety and pharmacokinetics of the dual action Raf kinase and vascular endothelial growth factor receptor inhibitor, BAY 43-9006, in patients with advanced, refractory solid tumors. Clin Cancer Res 2005; 11: 5472-80.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5472-5480
-
-
Clark, J.W.1
Eder, J.P.2
Ryan, D.3
Lathia, C.4
Lenz, H.J.5
-
10
-
-
33644833910
-
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma
-
Motzer RJ, Michaelson MD, Redman BG et al. Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and platelet-derived growth factor receptor, in patients with metastatic renal cell carcinoma. J Clin Oncol 2006; 24: 1-3.
-
(2006)
J Clin Oncol
, vol.24
, pp. 1-3
-
-
Motzer, R.J.1
Michaelson, M.D.2
Redman, B.G.3
-
11
-
-
1842451619
-
The role of 18F-FDG PET in staging and early prediction of response to therapy of recurrent gastrointestinal stromal tumors
-
Gayed I, Vu T, Iyer R et al. The role of 18F-FDG PET in staging and early prediction of response to therapy of recurrent gastrointestinal stromal tumors. J Nucl Med 2004; 45: 1803.
-
(2004)
J Nucl Med
, vol.45
, pp. 1803
-
-
Gayed, I.1
Vu, T.2
Iyer, R.3
-
12
-
-
11144354392
-
Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer
-
Willett CG, Boucher Y, di Tomaso E et al. Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer. Nat Med 2004; 10: 145-7.
-
(2004)
Nat Med
, vol.10
, pp. 145-147
-
-
Willett, C.G.1
Boucher, Y.2
Di Tomaso, E.3
-
14
-
-
0034778395
-
Soluble Tie2 and Flt1 extracellular domains in serum of patients with renal cancer and response to antiangiogenic therapy
-
Harris AL, Reusch P, Barleon B, Hang C, Dobbs N, Marme D. Soluble Tie2 and Flt1 extracellular domains in serum of patients with renal cancer and response to antiangiogenic therapy. Clin Cancer Res 2001; 7: 1992-7.
-
(2001)
Clin Cancer Res
, vol.7
, pp. 1992-1997
-
-
Harris, A.L.1
Reusch, P.2
Barleon, B.3
Hang, C.4
Dobbs, N.5
Marme, D.6
-
15
-
-
0030176365
-
Elevated serum E-selectin in patients with liver metastases of colorectal cancer
-
Wittig BM, Kaulen H, Thees R et al. Elevated serum E-selectin in patients with liver metastases of colorectal cancer. Eur J Cancer 1996; 32A: 1215-8.
-
(1996)
Eur J Cancer
, vol.32 A
, pp. 1215-1218
-
-
Wittig, B.M.1
Kaulen, H.2
Thees, R.3
-
16
-
-
0036023218
-
Soluble Tie-2 receptor levels independently predict locoregional recurrence in head and neck squamous cell carcinoma
-
Homer JJ, Greenman J, Drevs J, Marme D, Stafford ND. Soluble Tie-2 receptor levels independently predict locoregional recurrence in head and neck squamous cell carcinoma. Head Neck 2002; 24: 773-8.
-
(2002)
Head Neck
, vol.24
, pp. 773-778
-
-
Homer, J.J.1
Greenman, J.2
Drevs, J.3
Marme, D.4
Stafford, N.D.5
-
17
-
-
13844315197
-
Plasma vascular endothelial growth factor and serum soluble angiopoietin receptor sTIE-2 in patients with dural arteriovenous fistulas: A pilot study
-
Klisch J, Kubalek R, Scheufler KM, Zirrgiebel U, Drevs J, Schumacher M. Plasma vascular endothelial growth factor and serum soluble angiopoietin receptor sTIE-2 in patients with dural arteriovenous fistulas: a pilot study. Neuroradiology 2005; 47: 10-7.
-
(2005)
Neuroradiology
, vol.47
, pp. 10-17
-
-
Klisch, J.1
Kubalek, R.2
Scheufler, K.M.3
Zirrgiebel, U.4
Drevs, J.5
Schumacher, M.6
-
18
-
-
0842333189
-
Antiangiogenic potency of FK866/K22.175, a new inhibitor of intracellular NAD biosynthesis, in murine renal cell carcinoma
-
Drevs J, Loser R, Rattel B, Esser N. Antiangiogenic potency of FK866/K22.175, a new inhibitor of intracellular NAD biosynthesis, in murine renal cell carcinoma. Anticancer Res 2003; 23: 4853-8.
-
(2003)
Anticancer Res
, vol.23
, pp. 4853-4858
-
-
Drevs, J.1
Loser, R.2
Rattel, B.3
Esser, N.4
-
19
-
-
33751072158
-
2005 ASCO Annual Meeting Proceedings
-
Abstract No. 3002
-
Drevs J, Medinger M, Mross K et al. 2005 ASCO Annual Meeting Proceedings. J Clin Oncol 2005; 23: (Suppl.): Abstract No. 3002.
-
(2005)
J Clin Oncol
, vol.23
, Issue.SUPPL.
-
-
Drevs, J.1
Medinger, M.2
Mross, K.3
-
20
-
-
20944441692
-
Soluble markers for the assessment of biological activity with PTK787/ZK 222584 (PTK/ZK), a vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor in patients with advanced colorectal cancer from two phase I trials
-
Drevs J, Zirrgiebel U, Schmidt-Gersbach CI et al. Soluble markers for the assessment of biological activity with PTK787/ZK 222584 (PTK/ZK), a vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor in patients with advanced colorectal cancer from two phase I trials. Ann Oncol 2005; 16: 558-65.
-
(2005)
Ann Oncol
, vol.16
, pp. 558-565
-
-
Drevs, J.1
Zirrgiebel, U.2
Schmidt-Gersbach, C.I.3
-
21
-
-
33745162541
-
Angiogenesis inhibitors in a murine neuroblastoma model: Quantitative assessment of intratumoral blood flow with contrast-enhanced gray-scale US
-
McCarville MB, Streck CJ, Dickson PV, Li CS, Nathwani AC, Davidoff AM. Angiogenesis inhibitors in a murine neuroblastoma model: quantitative assessment of intratumoral blood flow with contrast-enhanced gray-scale US. Radiology 2006; 240: 73-81.
-
(2006)
Radiology
, vol.240
, pp. 73-81
-
-
McCarville, M.B.1
Streck, C.J.2
Dickson, P.V.3
Li, C.S.4
Nathwani, A.C.5
Davidoff, A.M.6
-
22
-
-
0034282515
-
Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model
-
Drevs J, Hofmann I, Hugenschmidt H, et al. Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model. Cancer Res 2000; 60: 4819-24.
-
(2000)
Cancer Res
, vol.60
, pp. 4819-4824
-
-
Drevs, J.1
Hofmann, I.2
Hugenschmidt, H.3
-
23
-
-
20444473802
-
Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours
-
Mross K, Drevs J, Muller M et al. Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours. Eur J Cancer 2005; 41: 1291-9.
-
(2005)
Eur J Cancer
, vol.41
, pp. 1291-1299
-
-
Mross, K.1
Drevs, J.2
Muller, M.3
-
24
-
-
33749339281
-
Comparison of cerebral blood volume and permeability in preoperative grading of intracranial glioma using CT perfusion imaging
-
[Epub ahead of print]
-
Ding B, Ling HW, Chen KM, Jiang H, Zhu YB. Comparison of cerebral blood volume and permeability in preoperative grading of intracranial glioma using CT perfusion imaging. Neuroradiology 2006 [Epub ahead of print].
-
(2006)
Neuroradiology
-
-
Ding, B.1
Ling, H.W.2
Chen, K.M.3
Jiang, H.4
Zhu, Y.B.5
-
25
-
-
33745963117
-
Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarker
-
Hylton N. Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarker. J Clin Oncol 2006; 24: 3293-8.
-
(2006)
J Clin Oncol
, vol.24
, pp. 3293-3298
-
-
Hylton, N.1
-
26
-
-
0347615101
-
Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases, in patients with advanced colorectal cancer and liver metastases: Results from two phase I studies
-
Morgan B, Thomas AL, Drevs J et al. Dynamic contrast-enhanced magnetic resonance imaging as a biomarker for the pharmacological response of PTK787/ZK 222584, an inhibitor of the vascular endothelial growth factor receptor tyrosine kinases, in patients with advanced colorectal cancer and liver metastases: results from two phase I studies. J Clin Oncol 2003; 21: 3955-64.
-
(2003)
J Clin Oncol
, vol.21
, pp. 3955-3964
-
-
Morgan, B.1
Thomas, A.L.2
Drevs, J.3
-
27
-
-
0025936268
-
Glucose uptake, perfusion, and cell proliferation in head and neck tumors: Relation of positron emission tomography to flow cytometry
-
Haberkorn U, Strauss LG, Reisser C et al. Glucose uptake, perfusion, and cell proliferation in head and neck tumors: relation of positron emission tomography to flow cytometry. J Nucl Med 1991; 32: 1548-55.
-
(1991)
J Nucl Med
, vol.32
, pp. 1548-1555
-
-
Haberkorn, U.1
Strauss, L.G.2
Reisser, C.3
-
28
-
-
0026560194
-
Measurements of blood flow and exchanging water space in breast tumors using positron emission tomography: A rapid and noninvasive dynamic method
-
Wilson CB, Lammertsma AA, McKenzie CG, Sikora K, Jones T. Measurements of blood flow and exchanging water space in breast tumors using positron emission tomography: a rapid and noninvasive dynamic method. Cancer Res 1992; 52: 1592-7.
-
(1992)
Cancer Res
, vol.52
, pp. 1592-1597
-
-
Wilson, C.B.1
Lammertsma, A.A.2
McKenzie, C.G.3
Sikora, K.4
Jones, T.5
-
29
-
-
0348223970
-
Assessment of inter- and intrapatient variability in C15O2 positron emission tomography measurements of blood flow in patients with intra-abdominal cancers
-
Wells P, Jones T, Price P. Assessment of inter- and intrapatient variability in C15O2 positron emission tomography measurements of blood flow in patients with intra-abdominal cancers. Clin Cancer Res 2003; 9: 6350-6.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 6350-6356
-
-
Wells, P.1
Jones, T.2
Price, P.3
-
30
-
-
0037108692
-
The development of [(124)I]iodinated-VG76e: A novel tracer for imaging vascular endothelial growth factor in vivo using positron emission tomography
-
Collingridge DR, Carroll VA, Glaser M et al. The development of [(124)I]iodinated-VG76e: a novel tracer for imaging vascular endothelial growth factor in vivo using positron emission tomography. Cancer Res 2002; 62: 5912-9.
-
(2002)
Cancer Res
, vol.62
, pp. 5912-5919
-
-
Collingridge, D.R.1
Carroll, V.A.2
Glaser, M.3
-
31
-
-
0027364877
-
Scintigraphic detection of xenografted tumors producing human basic fibroblast growth factor
-
Kobayashi H, Sakahara H, Hosono M et al. Scintigraphic detection of xenografted tumors producing human basic fibroblast growth factor. Cancer Immunol Immunother 1993; 37: 281-5.
-
(1993)
Cancer Immunol Immunother
, vol.37
, pp. 281-285
-
-
Kobayashi, H.1
Sakahara, H.2
Hosono, M.3
-
32
-
-
0035007106
-
In vivo evaluation of 111In-DTPA-N-TIMP-2 in Kaposi sarcoma associated with HIV infection
-
Kulasegaram R, Giersing B, Page CJ et al. In vivo evaluation of 111In-DTPA-N-TIMP-2 in Kaposi sarcoma associated with HIV infection. Eur J Nucl Med 2001; 28: 756-61.
-
(2001)
Eur J Nucl Med
, vol.28
, pp. 756-761
-
-
Kulasegaram, R.1
Giersing, B.2
Page, C.J.3
-
33
-
-
25444503494
-
Biodistribution and pharmacokinetics of the alphavbeta3-selective tracer 18F-galacto-RGD in cancer patients
-
Beer AJ, Haubner R, Goebel M et al. Biodistribution and pharmacokinetics of the alphavbeta3-selective tracer 18F-galacto-RGD in cancer patients. J Nucl Med 2005; 46: 1333-41.
-
(2005)
J Nucl Med
, vol.46
, pp. 1333-1341
-
-
Beer, A.J.1
Haubner, R.2
Goebel, M.3
|