Zirconyl chloride promoted highly efficient domino synthesis of new 1,2,3,4-tetrahydroquinoline derivatives in water

Chinese Chemical Letters

Volumn 17, Issue 9, 2006, Pages 1137-1140

  Nagawade, Rahul R ^a,b   Shinde, Devanand B ^b  

^a Wockhardt Research Centre   (India)

^b DR BABASAHEB AMBEDKAR MARATHWADA UNIVERSITY   (India)

Author keywords

Anilines; Cyclic enol ether; Domino reaction; Tetrahydroquinoline; Zirconyl chloride

Indexed keywords

EID: 33751061275     PISSN: 10018417     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

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24. 1H-NMR spectra, the signal of proton 10b was observed in the lower field and different from those of other protons. In addition, the coupling constant J (10b, 4b) in the eis isomer is larger than than that in trans isomer. Therefore, the ratio of two isomers was determined conveniently by comparing the integration of proton 1Ob of the two isomers. It was found that the eis isomer is the slightly more favored product in most cases of the reactions of substituted anilines with 3, 4-dihydro-2H-pyran.