Ample use of physician-prescribed medications in Finnish elite athletes

International Journal of Sports Medicine

Volumn 27, Issue 11, 2006, Pages 919-925

  Alaranta, Antti ^a   Alaranta, H ^b   Heliovaara M ^c   Airaksinen, M ^a   Helenius, I ^d  

^a UNIVERSITY OF HELSINKI   (Finland)

^b Kapyla Rehabilitation Centre   (Finland)

^c NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Adverse effects; Anti allergic medication; Anti asthmatic medication; Antibiotics; Non steroidal anti inflammatory drugs

Indexed keywords

ANTIALLERGIC AGENT; ANTIASTHMATIC AGENT; ANTIBIOTIC AGENT; ANTIDIABETIC AGENT; ANXIOLYTIC AGENT; CELECOXIB; DICLOFENAC; IBUPROFEN; INDOMETACIN; INSULIN; KETOPROFEN; MUSCLE RELAXANT AGENT; NAXOPREN; NEUROLEPTIC AGENT; NIMESULIDE; NONSTEROID ANTIINFLAMMATORY AGENT; ORAL CONTRACEPTIVE AGENT; OXICAM DERIVATIVE; PROPIONIC ACID DERIVATIVE; ROFECOXIB; UNCLASSIFIED DRUG;

ARTICLE; ASTHMA; ATHLETE; CONTROLLED STUDY; ENDURANCE; FEMALE; GASTROINTESTINAL SYMPTOM; HUMAN; MALE; PHYSICAL STRESS; PRESCRIPTION; PREVALENCE; QUESTIONNAIRE;

ADULT; ANTI-ALLERGIC AGENTS; ANTI-ASTHMATIC AGENTS; ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; EPIDEMIOLOGIC METHODS; FEMALE; FINLAND; HUMANS; MALE; SEX DISTRIBUTION; SPORTS;

EID: 33751057149     PISSN: 01724622     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-923811     Document Type: Article

References (38)

1. Adirim TA, Cheng TL. Overview of injuries in the young athlete. Sports Med 2003; 33: 75-81
2. Alaranta A, Alaranta H, Heliövaara M, Alha P, Palmu P, Helenius I. Allergic rhinitis and pharmacological management in elite athletes. Med Sci Sports Exerc 2005; 37: 707-711
3. 2-agonist overuse. Med Sci Sports Exerc 2004; 36: 919-924
4. Altman RD, Latta LL, Keer R, Renfree K, Hornicek FJ, Banovac K. Effect of nonsteroidal anti-inflammatory drugs on fracture healing: a laboratory study in rats. J Orthop Trauma 1995; 9: 392-400
5. Baker J, Cotter JD, Gerrard DF, Bell ML, Walker RJ. Effects of indomethacin and celecoxib on renal function in athletes. Med Sci Sports Exerc 2005; 37: 712-717
6. Bennell K, Brukner P. How should you treat a stress fracture? In: MacAuley D, Best T (eds). Evidence Based Sports Medicine. London: BMI Books, 2002; 491-517
7. Berglund B, Sundgot-Borgen J. Sports medicine update. Scand J Med Sci Sports 2001; 11: 369-371
8. Bondesen BA, Mills ST, Kegley KM, Pavlath GK. The COX-2 pathway is essential during early stages of skeletal muscle regeneration. Am J Physiol 2004; 287: C475-C483
9. Buckwalter JA. Pharmacological treatment of soft-tissue injuries. J Bone Joint Surg 1995; 77 A: 1902-1914
10. Burd TA, Lowry KJ, Anglen JO. Indomethacin compared with localized irradiation for the prevention of heterotopic ossification following surgical treatment of acetabular fractures. J Bone Joint Surg 2001; 83A: 1783-1788
11. Corrigan B, Kazlauskas R. Medication use in athletes selected for doping control at the Sydney Olympics (2000). Clin J Sports Med 2003; 13: 33-40
12. Crofford LJ, Wilber RL, Ristimäki AP, Sano H, Remmers EF, Epps HR, Hla T. Cyclooxygenase-1 and -2 expression in rheumatoid synovial tissues: effects of interleukin-1beta, phorbol ester, and corticosteroids. J Clin Invest Med 1994; 93: 1095-1101
13. Elder CL, Dahners LE, Weinhold PS. A cyclooxygenase-2 inhibitor impairs ligament healing in the rat. Am J Sports Med 2001; 29: 801-805
14. Endo K, Sairyo K, Komatsubara S, Sasa T, Egawa H, Yonekura D, Adachi K, Ogawa T, Murakami R, Yasui N. Cyclooxygenase-2 inhibitor inhibits the fracture healing. J Physiol Anthropol Appl Human Sci 2002; 21: 235-238
15. Gierer P, Mittlmeier T, Bordel R, Schaser KD, Gradl G, Vollmar B. Selective cyclooxygenase-2 inhibition reverses microcirculatory and inflammatory sequelae of closed soft-tissua trauma in an animal model. J Bone Joint Surg 2005; 87A: 153-160
16. Gilroy DW, Tomlinson A, Willoughby DA. Differential effects of inhibition of isoforms of cyclooxygenase (COX-1, COX-2) in chronic inflammation. Inflamm Res 1998; 47: 79-85
17. Gretzer B, Knorth H, Chantrain M, Barbera L, Willburger RE, Wittenberg RH, Peskar BM. Effects of diclofenac and L-745, 337, a selective cyclooxigenase-2 inhibitor, on prostaglandin E2 formation in tissue from human colonic mucosa and chronic bursitis. Gastroenterology 1998; 114: A139
18. Griffiths ML. End-stage renal failure caused by regular use of anti-inflammatory analgesic medication for minor sports injuries. S Afr Med J 1992; 81: 377-378
19. Hawkey CJ, Langman MS. Non-steroidal anti-inflammatory drugs: overall risks and management. Complementary roles for COX-2 inhibitors and proton pump inhibitors. Gut 2003; 52: 600-608
20. Helbling A, Jenoure P, Muller U. The incidence of hay fever in leading Swiss athletes. Schweiz Med Wschr 1990; 120: 231-236
21. Helenius I, Rytilä P, Sarna S, Lumme A, Helenius M, Remes V, Haahtela T. Effect of continuing or finishing high-level sports on airway inflammation, bronchial hyperresponsiveness, and asthma: a 5-year prospective follow-up study of 42 highly trained swimmers. J Allergy Clin Immunol 2002; 109: 962-968
22. Helenius IJ, Tikkanen HO, Haahtela T. Association between type of training and risk of asthma in elite athletes. Thorax 1997; 52: 157-160
23. Irving RA, Noakes TD, Raine RI, Van Zyl Smit R. Transient oliguria with renal tubular dysfunction after a 90 km running race. Med Sci Sports Exerc 1990; 22: 756-761
24. Kujala UM, Sarna S, Kaprio J. Use of medications and dietary supplements in later years among male former top-level athletes. Arch Int Med 2003; 163: 1064-1068
25. Kujala UM, Taimela S, Antti-Poika I, Orava S, Tuominen R, Myllynen P. Acute injuries in soccer, ice hockey, volleyball, basketball, judo, and karate: analysis of national registry data. BMJ 1995; 311: 1465-1468
26. Maiolo C, Fuso L, Todaro A, Anatra F, Boniello V, Basso S, De Lorenzo A, Pistelli R. Asthma and atopy in elite athletes. Int J Sports Med 2003; 24: 139-144
27. Nieman DC. Exercise effects on systemic immunity. Immunol Cell Biol 2000; 78: 496-501
28. Nystad W, Harris J, Sundgot Borgen J. Asthma and wheezing among Norwegian elite athletes. Med Sci Sports Exerc 2000; 32: 266-270
29. Seibert K, Zhang Y, Leahy K, Hauser S, Masferrer J, Isakson P. Distribution of COX-1 and COX-2 in normal and inflamed tissues. Adv Exp Med Biol 1997; 400A: 167-170
30. Shoor S. Athletes, nonsteroidal anti-inflammatory drugs, coxibs, and the gastrointestinal tract. Curr Sports Med Reports 2002; 1: 107-115
31. Simon LS. Actions and toxicity of non-steroidal anti-inflammatory drugs. Curr Opin Rheumat 1996; 5: 169-175
32. Szczeklik A, Gryglewski RJ, Czerniawska-Mysik G, Pieton R. Asthmatic attacks induced in aspirin-sensitive patients by diclofenac and naxopren. BMJ 1977; 2: 231-232
33. Thorsson O, Rantanen J, Hurme T, Kalimo H. Effects of nonsteroidal antiinflammatory medication on satellite cell proliferation during muscle regeneration. Am J Sports Med 1998; 26: 172-176
34. Verrico MM, Weber RJ, McKaveney TP, Ansani NT, Towers AL. Adverse drug events involving COX-2 inhibitors. Ann Pharmacother 2003; 37: 1203-1213
35. Vitting KE, Nichols NJ, Seligson GR. Naproxen and acute renal failure in a runner. Ann Intern Med 1986; 105: 44
36. Walker RJ, Fawcett JP, Flannery EM, Gerrard DF. Indomethacin potentiates exercise-induced reduction in renal hemodynamics in athletes. Med Sci Sports Exerc 1994; 26: 1302-1306
37. Wallace JL, Chapman K, McKnight W. Limited anti-inflammatory efficacy of cyclo-oxygenase-2 inhibition in carrageenan-airpouch inflammation. Br J Pharmacol 1999; 126: 1200-1204
38. Weiler JM. Medical modifiers of sport injury. The use of nonsteroidal anti-inflammatory drugs (NSAIDs) in sports soft-tissue injury. Clin Sports Med 1992; 11: 625-644