Emergency admissions for upper gastrointestinal disease and their relation to NSAID use

Alimentary Pharmacology and Therapeutics

Volumn 11, Issue 2, 1997, Pages 283-291

  Blower, A L ^a   Brooks, A ^b   Fenn, G C ^c,e   Hill, A ^d   Pearce, M Y ^c   Morant, S ^c   Bardhan, K D ^b  

^a ROYAL ALBERT EDWARD INFIRMARY   (United Kingdom)

^b ROTHERHAM GENERAL HOSPITAL   (United Kingdom)

^c Searle   (United Kingdom)

^d STEPPING HILL HOSPITAL   (United Kingdom)

^e Searle Medical Department   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

NONSTEROID ANTIINFLAMMATORY AGENT;

ARTICLE; DRUG USE; EMERGENCY MEDICINE; GASTROINTESTINAL DISEASE; HOSPITALIZATION; HUMAN; MORBIDITY; MORTALITY; PRIORITY JOURNAL;

EID: 0030939516     PISSN: 02692813     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2036.1997.d01-604.x     Document Type: Article

References (30)

1. Cockel R. NSAIDs - should every prescription carry a government health warning? Gut 1987; 28: 515-8.
2. Armstrong CP, Blower AL. Non steroidal anti-inflammatory drugs and life threatening complications of peptic ulceration. Gut 1987; 28: 527-52.
3. Quader K, Logan RFA. Peptic ulcer (PU) deaths: how many occur at home or after non-steroidal anti-inflammatory drug (NSAID) prescribing? Gut 1988; 29: A1443(Abstract).
4. Paulus HE. FDA Arthritis Advisory Committee meeting: Serious gastrointestinal toxicity of nonsteroidal anti-inflammatory drugs. Arthritis Rheum 1988; 31: 1450-1.
5. Beardon PHG, Brown SV, McDevitt DG. Gastrointestinal events in patients prescribed non-steroidal anti-inflammatory drugs: A controlled study using record linkage in Tayside. Q J Med 1989; 71: 497-505.
6. Faulkner G, Prichard P, Somerville K, Langman MJS. Aspirin and bleeding peptic ulcers in the elderly. Br Med J 1988; 297: 1311-13.
7. Shorrock CJ, Langman MJS, Warlow C. Risks of upper GI bleeding during TIA prophylaxis with aspirin. Gut 1995; 37: 509-11.
8. Hawkey CJ. Non steroidal anti-inflammatory drugs and peptic ulcers. Br Med J 1990; 300: 278-84.
9. Griffin MR, Piper JM, Daugherty JR, et al. Non steroidal anti-inflammatory drug use and increased risk for peptic ulcer disease in elderly persons. Ann Intern Med 1991; 114: 257-63.
10. Carson JL, Strom BL, Soper KA, West SL, Morse ML. The association of non-steroidal anti-inflammatory drugs with upper gastrointestinal tract bleeding. Arch Intern Med 1987; 147: 85-8.
11. Gabriel SE, Jaakkimainen L, Bombardier C. Risks for serious gastrointestinal complications related to use of non-steroidal anti-inflammatory drugs. Ann Intern Med 1991; 115: 787-96.
12. Somerville K, Faulkner G, Langman M. Non-steroidal anti-inflammatory drugs and bleeding peptic ulcer. Lancet 1986; i: 462-4.
13. Garcia Rodriguez LA, Jick H. Risk of upper gastrointestinal bleeding and perforation associated with individual non-steroidal anti inflammatory drugs. Lancet 1994; 343: 769-72.
14. Langman MJS, Brooks P, Hawkey CJ, Silverstein F, Yeomans N. Non-steroidal anti-inflammatory drug associated ulcer: Epidemiology causation and treatment. J Gastroenterol Hepatol 1991; 6: 442-9.
15. Langman MJS, Weil J, Wainwright P, et al. Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs. Lancet 1994; 343: 1075-8.
16. Bollini P, Garcia Podriquez LA. Gutthann SP, Walker AM. The impact of research quality and study design on epidemiologic estimates of the effect of non-steroidal anti-inflammatory drugs on upper gastrointestinal tract disease. Arch Intern Med 1992; 152: 1289-95.
17. Greater Manchester County Monitor OPCS Census 91: CM18. September 1992.
18. South Yorkshire County Monitor OPCS Census 91: CM37. June 1992.
19. National Monitor UK OPCS Census 91: CM56, December 1992.
20. Brown, KC, Langman MJS, Lambert PM. Hospital admissions for peptic ulcer during 1958-72. Br Med J 1976; 1: 35-7.
21. IMS Data on File; data reproduced with permission. Source: Regional Sales Analysis (IMS Ltd).
22. McCullagh P, Nelder JA. Generalized Linear Models. 3rd edn. London: Chapman & Hall, 1991.
23. Collier D, St J, Pain JA. Non-steroidal anti-inflammatory drugs and peptic ulcer perforation. Gut 1985; 26: 359-63.
24. Masson J, Bramley P, Herd K, et al. Prior use of Aspirin, NSAIDs and ulcer healing drugs in upper gastrointestinal bleeding presenting to an open access endoscopy unit. Gut 1993; 34(4) Suppl.: S39.
25. Rockall TA, Logan RFA, Devlin HB, Northfield TC. Incidence of and mortality from acute upper gastrointestinal haemorrhage in the UK. Br Med J 1995; 311: 222-6.
26. Jones SC, Axon ATR. Bleeding peptic ulcer - endoscopic and pharmacological management. Postgrad Med J 1991; 67: 606-12.
27. Bloom BS. Cross national changes in the effects of peptic ulcer disease. American College of Physicians 1991; 114: 558-62.
28. Silverstein FE. NSAIDs and gastrointestinal injury: clinical outcome, the MUCOSA trial. Ann Intern Med 1995; 123(4): 241-9.
29. Smally WE, Griffin MR, Daugherty J. Hospitalisation for ulcer related diseases in the elderly medicaid population. Gastroenterology 1992; 102 (4 part 2): A25(Abstract).
30. Blower AL, Armstrong CP. Ulcer perforation in the elderly and non-steroidal anti-inflammatory drugs. Lancet 1986; i: 97.