Medium-term tongue carcinogenesis assays: A comparative study between 4-nitroquinoline 1-oxide (4NQO)-induced rat and dimethylbenzanthracene (DMBA)-induced hamster carcinogenesis

Journal of Experimental Animal Science

Volumn 43, Issue 3, 2006, Pages 219-227

  Kitakawa, D ^a   Cabral, L A G ^a   Marques, M E A ^a   Salvadori, D M F ^a   Ribeiro, D A ^a,b  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Hamster; Rat; Tongue carcinogenesis

Indexed keywords

4 NITROQUINOLINE 1 OXIDE; ACETONE; DIMETHYLBENZ[A]ANTHRACENE; DRINKING WATER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOASSAY; CANCER GRADING; CANCER MODEL; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CONTROLLED STUDY; DYSPLASIA; EXPERIMENTAL ANIMAL; HAMSTER; HISTOPATHOLOGY; HYPERKERATOSIS; HYPERPLASIA; MALE; NONHUMAN; RAT; SQUAMOUS CELL CARCINOMA; TONGUE CANCER;

ANIMALIA; CRICETINAE; MESOCRICETUS AURATUS; RATTUS NORVEGICUS;

EID: 33750977542     PISSN: 09398600     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jeas.2006.09.001     Document Type: Article

References (19)

1. Cairns J. Mutational section and the natural history of cancer. Nature 255 (1975) 197-200
2. Chen Y.K., Hsue S.S., and Lin L.M. Immunohistochemical demonstration of p63 in DMBA-induced hamster buccal pouch squamous cell carcinogenesis. Oral. Dis. 9 (2003) 235-240
3. Evenson J.W., and Mc Donald D.G. Hamster tongue carcinogenesis I. Characteristics of the experimental model. J. Oral Pathol. Med. 10 (1981) 322-331
4. Hahn M., Hagedorn G., Kuhlisch E., Schackert H.K., and Edkelt U. Genetic polymorphisms of drug-metabolizing enzymes and susceptibility to oral cavity cancer. Oral. Oncol. 38 (2002) 486-490
5. Ito N. In vivo carcinogenesis of 4-nitroquinoline 1-oxide and related compounds. Carcinog. Compr. Surv. 6 (1981) 117-153
6. Kandarkar S.V., Sawant S.S., and Reade P.C. Ultrastructural changes to the palatal mucosa of rats following the application of 4-nitroquinoline 1-oxide (4NQO) and vitamin C. Oral. Oncol. 34 (1998) 247-252
7. Kramer I.R., Lucas R.B., and Pindborg J.J. Definition of leukoplakia and related lesions: an aid to studies on oral precancer. Oral. Surg. 46 (1978) 518-539
8. Magrath I., and Litvak J. Cancer in developing countries: opportunity and challenge. J. Natl. Cancer Inst. 85 (1993) 862-874
9. Nakaya H., Kawashiri S., Tanaka A., Noguchi N., Kato K., Hase T., and Yamamoto E. Influence of angiogenesis and lymphangiogenesis on cancerous invasion in experimentally induced carcinoma. J. Oral. Pathol. Med. 34 (2005) 87-92
10. Nishimura A. Changes in Bcl-2 and Bax expression in rat tongue during 4-nitroquinoline 1-oxide-induced carcinogenesis. J. Dent. Res. 78 (1999) 1264-1269
11. Ohne M., Satoh T., Yamada S., and Takai H. Experimental tongue carcinoma of rats induced by oral administration of 4-nitroquinoline 1-oxide (4NQO) in drinking water. Oral Surg. Oral Med. Oral Pathol. 59 (1985) 600-607
12. Okazaki Y., Tanaka Y., Tonogi M., and Yamane G. Investigation of environmental factors for diagnosing malignant potential in oral epithelial dysplasia. Oral. Oncol. 38 (2002) 562-573
13. Ribeiro D.A., Salvadori D.M.F., Silva R.N., Darros B.R., and Marques M.E.A. Genomic instability in non-neoplastic oral mucosa cells can predict risk during 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. Oral. Oncol. 40 (2004) 910-915
14. Ribeiro D.A., Salvadori D.M., and Marques M.E. Abnormal expression of bcl-2 and bax in rat tongue mucosa during the development of squamous cell carcinoma induced by 4-nitroquinoline 1-oxide. Int. J. Exp. Pathol. 86 (2005) 375-381
15. Rojas M., Cascorbi I., Alexandrov K., Kriek E., Auburtin G., and Mayer L. Modulation of benzo[a]pyerene diolepoxide-DNA adduct levels in human white blood cells by CYP1A1, GSTM1 and GSTT1 polymorphism. Carcinogenesis 20 (1999) 1927-1931
16. Schwartz J.L., Gu X., Kittles R.A., Baptiste A., and Shklar G. Experimental oral carcinoma of the tongue and buccal mucosa: possible biologic markers linked to cancers at two anatomic sites. Oral. Oncol. 36 (2000) 225-235
17. Tanaka T., Kohno H., Sakata K., Yamada Y., Hirose Y., Sugie S., and Mori H. Modifying effects of dietary capsaicin and rotenone on 4-nitroquinoline 1-oxide induced rat tongue carcinogenesis. Carcinogenesis 23 (2002) 1361-1367
18. Vered M., Daniel N., Hirshberg A., and Dayan D. Histomorphologic and morphometric changes in minor salivary glands of the rat tongue during 4-nitroquinoline 1-oxide-induced carcinogenesis. Oral. Oncol. 39 (2003) 491-496
19. Wada S., Tazawa K., Furuta I., and Nagae H. Antitumor effect of new local hyperthermia using dextran magnetite complex in hamster tongue carcinoma. Oral. Dis. 9 (2003) 218-223