Primary somatosensory cortex is actively involved in pain processing in human

Brain Research

Volumn 853, Issue 2, 2000, Pages 282-289

  Kanda, Masutaro ^a,b   Nagamine, Takashi ^a   Ikeda, Akio ^a   Ohara, Shinji ^a   Kunieda, Takeharu ^a   Fujiwara, Naohito ^a   Yazawa, Shogo ^a   Sawamoto, Nobukatsu ^a   Matsumoto, Riki ^a   Taki, Waro ^c   Shibasaki, Hiroshi ^a  

^a KYOTO UNIVERSITY   (Japan)

^b 601 1495   (Japan)

^c MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Human; Magnetoencephalogram; Pain perception; Parallel processing; Primary somatosensory cortex (SI); Subdural recording

Indexed keywords

ADULT; ARTICLE; CARBON DIOXIDE LASER; CASE REPORT; CONTROLLED STUDY; ELECTROSTIMULATION; EPILEPSY; HAND; HUMAN; HUMAN EXPERIMENT; IRRADIATION; MAGNETOENCEPHALOGRAPHY; MALE; NERVE STIMULATION; NORMAL HUMAN; PAIN; PRIORITY JOURNAL; SOMATOSENSORY CORTEX; TECHNIQUE;

ADULT; BRAIN MAPPING; BRAIN NEOPLASMS; ELECTRIC STIMULATION; ELECTRODES, IMPLANTED; ELECTROOCULOGRAPHY; EPILEPSIES, PARTIAL; EVOKED POTENTIALS, SOMATOSENSORY; FRONTAL LOBE; HAND; HUMANS; INFRARED RAYS; LASERS; MAGNETOENCEPHALOGRAPHY; MALE; MEDIAN NERVE; PAIN; PHYSICAL STIMULATION; REACTION TIME; REFERENCE VALUES; SKIN PHYSIOLOGY; SOMATOSENSORY CORTEX; WRIST;

EID: 0033986086     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)02274-X     Document Type: Article

References (48)

1. Adriaensen H., Gybels J., Handwerker H.O., Van Hees J. Response properties of thin myelinated (A-delta) fibers in human skin nerves. J. Neurophysiol. 49:1983;111-122.
2. Ahonen A.I., Hämäläinen M.S., Kajola M.J., Knuutila J.E.T., Laine P.P., Lounasmaa O.V.L., Parkkonen L.T., Simola J.T., Tesche C.D. 122-channel SQUID instrument for investigation the magnetic signals from the human brain. Phys. Scr. T. 49:1993;198-205.
3. Allison T., McCarthy G., Wood C.C., Darcey T.M., Spencer D.D., Williamson P.D. Human cortical potentials evoked by stimulation of the median nerve: I. Cytoarchitectonic areas generating short-latency activity. J. Neurophysiol. 62:1989;694-710.
4. Allison T., Wood C.C., McCarthy G., Spencer D.D. Cortical somatosensory evoked potentials: II. Effects of excision of somatosensory or motor cortex in humans and monkeys. J. Neurophysiol. 66:1991;64-82.
5. Andersson J.L., Lilja A., Hartvig P., Langstrom B., Gordh T., Handwerker H., Torebjork E. Somatotopic organization along the central sulcus, for pain localization in humans, as revealed by positron emission tomography. Exp. Brain Res. 117:1997;192-199.
6. Baumgartner C., Doppelbauer A., Sutherling W.W., Zeitlhofer J., Lindinger G., Lind C., Deecke L. Human somatosensory cortical finger representation as studied by combined neuromagnetic and neuroelectric measurements. Neurosci. Lett. 134:1991;103-108.
7. 2 laser stimuli causing pain. Exp. Brain Res. 67:1987;153-162.
8. Carmon A., Mor J., Goldberg J. Evoked cerebral responses to noxious thermal stimuli in humans. Exp. Brain Res. 25:1976;103-107.
9. Casey K.L., Minoshima S., Morrow T.J., Koeppe R.A. Comparison of human cerebral activation pattern during cutaneous warmth, heat pain, and deep cold pain. J. Neurophysiol. 76:1996;571-581.
10. Chudler E.H., Anton F., Dubner R., Kenshalo D.R. Jr. Responses of nociceptive SI neurons in monkeys and pain sensation in humans elicited by noxious thermal stimulation: effect of interstimulus interval. J. Neurophysiol. 63:1990;559-569.
11. Coghill R.C., Talbot J.D., Evans A.C., Meyer E., Gjedde A., Bushnell M.C., Duncan G.H. Distributed processing of pain and vibration by the human brain. J. Neurosci. 14:1994;4095-4108.
12. Davis K.D., Kwan C.L., Crawley A.P., Mikulis D.J. Functional MRI study of thalamic and cortical activations evoked by cutaneous heat, cold, and tactile stimuli. J. Neurophysiol. 80:1998;1533-1546.
13. Derbyshire S.W., Jones A.K., Gyulai F., Clark S., Townsend D., Firestone L.L. Pain processing during three levels of noxious stimulation produces differential patterns of central activity. Pain. 73:1997;431-445.
14. Desmedt J.E., Cheron G. Central somatosensory conduction in man: neural generators and interpeak latencies of the far-field components recorded from neck and right or left scalp and earlobes. Electroencephalogr. Clin. Neurophysiol. 50:1980;382-403.
15. Disbrow E., Buonocore M., Antognini J., Carstens E., Rowley H.A. Somatosensory cortex: a comparison of the response to noxious thermal, mechanical, and electrical stimuli using functional magnetic resonance imaging. Hum. Brain Mapp. 6:1998;150-159.
16. Dostrovsky J.O., Craig A.D. Cooling-specific spinothalamic neurons in the monkey. J. Neurophysiol. 76:1996;3656-3665.
17. Garraghty P.E., Florence S.L., Tenhula W.N., Kaas J.H. Parallel thalamic activation of the first and second somatosensory areas in prosimian primates and tree shrews. J. Comp. Neurol. 311:1991;289-299.
18. 2 stimulation of the human nasal mucosa. Pain. 72:1997;145-151.
19. Hämäläinen M., Hari R., Ilmoniemi R., Knuutila J., Lounasmaa O.V. Magnetoencephalography-theory, instrumentation, and application to noninvasive studies of the working human brain. Rev. Mod. Phys. 65:1993;413-497.
20. Howland E.W., Wakai R.T., Mjaanes B.A., Balog J.P., Cleeland C.S. Whole head mapping of magnetic fields following painful electric finger shock. Brain Res., Cogn. Brain Res. 2:1995;165-172.
21. 2 stimulation of nasal mucosa: a magnetoencephalographic study in man. Electroencephalogr. Clin. Neurophysiol. 64:1986;347-349.
22. Jones A.K., Brown W.D., Friston K.J., Qi L.Y., Frackowiak R.S. Cortical and subcortical localization of response to pain in man using positron emission tomography. Proc. R. Soc. London, Ser. B. 244:1991;39-44.
23. 2 laser stimulation in man. Neurosci. Lett. 192:1995;45-48.
24. 2 laser stimulation in man. Electroencephalogr. Clin. Neurophysiol. 74:1989;139-146.
25. 2 laser stimulation in man. Electroencephalogr. Clin. Neurophysiol. 100:1996;105-114.
26. Kenshalo D.R. Jr., Chudler E.H., Anton F., Dubner R. SI nociceptive neurons participate in the encoding process by which monkeys perceive the intensity of noxious thermal stimulation. Brain Res. 454:1988;378-382.
27. Kenshalo D.R. Jr., Isensee O. Responses of primate SI cortical neurons to noxious stimuli. J. Neurophysiol. 50:1983;1479-1496.
28. Kitamura Y., Kakigi R., Hoshiyama M., Koyama S., Shimojo M., Watanabe S. Pain-related somatosensory evoked magnetic fields. Electroencephalogr. Clin. Neurophysiol. 95:1995;463-474.
29. Kitamura Y., Kakigi R., Hoshiyama M., Koyama S., Watanabe S., Shimojo M. Pain-related somatosensory evoked magnetic fields following lower limb stimulation. J. Neurol. Sci. 145:1997;187-194.
30. Lenz F.A., Rios M., Chau D., Krauss G.L., Zirh T.A., Lesser R.P. Painful stimuli evoke potentials recorded from the parasylvian cortex in humans. J. Neurophysiol. 80:1998;2077-2088.
31. McCarthy G., Wood C.C., Allison T. Cortical somatosensory evoked potentials: I. Recordings in the monkey Macaca fascicularis. J. Neurophysiol. 66:1991;53-63.
32. Mima T., Nagamine T., Nishitani N., Mikuni N., Ikeda A., Fukuyama H., Takigawa T., Kimura J., Shibasaki H. Cortical myoclonus: sensorimotor hyperexcitability. Neurology. 50:1998;933-942.
33. 2 laser stimulation of the hand: scalp topography and effect of predictive warning signal. J. Clin. Neurophysiol. 11:1994;242-254.
34. Nagamine T., Makela J., Mima T., Mikuni N., Nishitani N., Satoh T., Ikeda A., Shibasaki H. Serial processing of the somesthetic information revealed by different effects of stimulus rate on the somatosensory-evoked potentials and magnetic fields. Brain Res. 791:1998;200-208.
35. Ploner M., Schmitz F., Freund H.J., Schnitzler A. Parallel activation of primary and secondary somatosensory cortices in human pain processing. J. Neurophysiol. 81:1999;3100-3104.
36. Pons T.P., Garraghty P.E., Mishkin M. Serial and parallel processing of tactual information in somatosensory cortex of rhesus monkeys. J. Neurophysiol. 68:1992;518-527.
37. Rainville P., Duncan G.H., Price D.D., Carrier B., Bushnell M.C. Pain affect encoded in human anterior cingulate but not somatosensory cortex. Science. 277:1997;968-971.
38. Scherg M., Picton T.W. Separation and identification of event-related potential components by brain electric source analysis. Electroencephalogr. Clin. Neurophysiol., Suppl. 42:1991;24-37.
39. Scherg M., Von Cramon D. Evoked dipole source potentials of the human auditory cortex. Electroencephalogr. Clin. Neurophysiol. 65:1986;344-360.
40. Talbot J.D., Marrett S., Evans A.C., Meyer E., Bushnell M.C., Duncan G.H. Multiple representations of pain in human cerebral cortex. Science. 251:1991;1355-1358.
41. Treede R.D., Kief S., Hölzer T., Bromm B. Late somatosensory evoked cerebral potentials in response to cutaneous heat stimuli. Electroencephalogr. Clin. Neurophysiol. 70:1988;429-441.
42. Treede R.D., Meyer R.A., Raja S.N., Campbell J.N. Evidence for two different heat transduction mechanisms in nociceptive primary afferents innervating monkey skin. J. Physiol. (London). 483:1995;747-758.
43. Uusitalo M.A., Ilmoniemi R.J. Signal-space projection method for separating MEG or EEG into components. Med. Biol. Eng. Comput. 35:1997;135-140.
44. Vogt B.A., Derbyshire S., Jones A.K. Pain processing in four regions of human cingulate cortex localized with co-registered PET and MR imaging. Eur. J. Neurosci. 8:1996;1461-1473.
45. Watanabe S., Kakigi R., Koyama S., Hoshiyama M., Kaneoke Y. Pain processing traced by magnetoencephalography in the human brain. Brain Topogr. 10:1998;255-264.
46. Wood C.C., Spencer D.D., Allison T., McCarthy G., Williamson P.D., Goff W.R. Localization of human sensorimotor cortex during surgery by cortical surface recording of somatosensory evoked potentials. J. Neurosurg. 68:1988;99-111.
47. Xu X., Fukuyama H., Yazawa S., Mima T., Hanakawa T., Magata Y., Kanda M., Fujiwara N., Shindo K., Nagamine T., Shibasaki H. Functional localization of pain perception in the human brain studied by PET. NeuroReport. 8:1997;555-559.
48. Xu X., Kanda M., Shindo K., Fujiwara N., Nagamine T., Ikeda A., Honda M., Tachibana N., Barrett G., Kaji R., Kimura J., Shibasaki H. Pain-related somatosensory evoked potentials following C02 laser stimulation of foot in man. Electroencephalogr. Clin. Neurophysiol. 96:1995;12-23.