Neuropsychological effects of risperidone in children with pervasive developmental disorders: A blinded discontinuation study

Journal of Child and Adolescent Psychopharmacology

Volumn 16, Issue 5, 2006, Pages 561-573

  Troost, Pieter W ^a   Althaus, Monika ^a   Lahuis, Bertine E ^b   Buitelaar, Jan K ^c   Minderaa, Ruud B ^a   Hoekstra, Pieter J ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; CENTRAL STIMULANT AGENT; PLACEBO; RISPERIDONE;

ADOLESCENT; ARTICLE; ATTENTION; AUTISM; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISRUPTIVE BEHAVIOR; DRUG EFFICACY; FEMALE; HUMAN; MALE; NEUROPSYCHOLOGY; OPEN STUDY; RANDOMIZED CONTROLLED TRIAL; RESPONSE TIME; TASK PERFORMANCE; TREATMENT WITHDRAWAL;

ADOLESCENT; AGGRESSION; ANTIPSYCHOTIC AGENTS; ATTENTION; CHILD; CHILD BEHAVIOR DISORDERS; CHILD DEVELOPMENT DISORDERS, PERVASIVE; CHILD, PRESCHOOL; CHOICE BEHAVIOR; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; HUMANS; MALE; MEMORY, SHORT-TERM; NEUROPSYCHOLOGICAL TESTS; PATTERN RECOGNITION, VISUAL; REACTION TIME; RISPERIDONE; SELF-INJURIOUS BEHAVIOR; SERIAL LEARNING;

EID: 33750957325     PISSN: 10445463     EISSN: None     Source Type: Journal    
DOI: 10.1089/cap.2006.16.561     Document Type: Article

References (33)

1. Althaus M, de Sonneville L, Minderaa RB, Hensen L, Til RB: Information processing and aspects of visual attention in children with the DSM-III-R diagnosis "Pervasive Developmental Disorder Not Otherwise Specified" (PDDNOS): I. Focused and divided attention. Child Neuropsychol 2:17-29, 1996.
2. Althaus M, Mulder LJ, Mulder G, Aarnoudse CC, Minderaa RB: Cardiac adaptivity to attention-demanding tasks in children with a pervasive developmental disorder not otherwise specified (PDD-NOS). Biol Psychiatry 46:799-809, 1999.
3. Aman MG, Singh NN, Stewart AW, Field CJ: The Aberrant Behavior Checklist: A behavior rating scale for the assessment of treatment effects. Am J Ment Defic 89:485-491, 1985.
4. Aman MG, Arnold LE, McDougle CJ, Vitiello B, Scahill L, Davies M, McCracken JT, Tierney E, Nash PL, Posey DJ, Chuang S, Martin A, Shah B, Gonzalez NM, Swiezy NB, Ritz L, Koenig K, McGough J, Ghuman JK, Lindsay RL: Acute and long-term safety and tolerability of risperidone in children with autism. J Child Adolesc Psychopharmacol 15:869-884, 2005.
5. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed., Text Revision (DSM-IV-TR). Washington, DC, American Psychiatric Association, 2000.
6. Bennetto L, Pennington BF, Rogers SJ, Intact and impaired memory functions in autism. Child Dev 67:1816-1835, 1996.
7. De Sonneville L. SVAT: A computer-based approach to development and disorders of information processing. In: Computers in Psychology: Tools for Experimental and Applied Psychology. Edited by Maarse FJ, Akkerman AE, Brand N, Mulder LJM, van der Stelt M. Lisse, Swets and Zeitlinger, 1993, pp 168-176.
8. Findling RL, Aman MG, Eerdekens ME, Derivan A, Lyons B: Long-term, open-label study of risperidone in children with severe disruptive behaviors and below-average IQ. Am J Psychiatry 161:677-684, 2004.
9. Guy W: Assessment Manual for Psychopharmacology, Revised. Bethesda, (Maryland), U.S. Department of Health, Education and Welfare, 1976.
10. Harvey PD, Green MF, McGurk SR, Meltzer HY: Changes in cognitive functioning with risperidone and olanzapine treatment: A large-scale, double-blind, randomized study. Psychopharmacology (Berl) 169:404-411, 2003.
11. Haznedar MM, Buchsbaum MS, Metzger M, Solimando A, Spiegel-Cohen J, Hollander E: Anterior cingulate gyrus volume and glucose metabolism in autistic disorder. Am J Psychiatry 154:1047-1050, 1997.
12. Haznedar MM, Buchsbaum MS, Wei TC, Hof PR, Cartwright C, Bienstock CA, Hollander E: Limbic circuitry in patients with autism spectrum disorders studied with positron emission tomography and magnetic resonance imaging. Am J Psychiatry 157:1994-2001, 2000.
13. Keefe RS, Silva SG, Perkins DO, Lieberman JA: The effects of atypical antipsychotic drugs on neurocognitive impairment in schizophrenia: A review and meta-analysis. Schizophr Bull 25:201-222, 1999.
14. Koshino H, Carpenter PA, Minshew NJ, Cherkassky VL, Keller TA, Just MA: Functional connectivity in an fMRI working memory task in high-functioning autism. Neuroimage 24:810-821, 2005.
15. Landa RJ, Goldberg MC: Language, social, and executive functions in high functioning autism: A continuum of performance. J Autism Dev Disord 35:557-573, 2005.
16. Levitt JG, Blanton RE, Smalley S, Thompson PM, Guthrie D, McCracken JT: Cortical sulcal maps in autism. Cereb Cortex 13:728-735, 2003.
17. Lord C, Rutter M, Le Couteur A: Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. J Autism Dev Disord 24:659-685, 1994.
18. Luna B, Minshew NJ, Carver KE, Lazar NA, Thulborn KR, Eddy WF: Neocortical system abnormalities in autism: An fMRI study of spatial working memory. Neurology 59:834-840, 2002.
19. McDougle CJ, Scahill L, Aman MG, McCracken JT, Tierney E, Davies M, Arnold LE, Posey DJ, Martin A, Ghuman JK, Shah B, Chuang SZ, Swiezy NB, Gonzalez NM, Hollway J, Koenig K, McGough JJ, Ritz L, Vitiello B: Risperidone for the core symptom domains of autism: Results from the study by the autism network of the research units on pediatric psychopharmacology. Am J Psychiatry 162:1142-1148, 2005.
20. Ozonoff S, Jensen J: Brief report: Specific executive function profiles in three neurodevelopmental disorders. J Autism Dev Disord 29:171-177, 1999.
21. Patel NC, Crismon ML, Hoagwood K, Johnsrud M, Rascati KL, Wilson JP, Jensen PS: Trends in the use of typical and atypical antipsychotics in children and adolescents. J Am Acad Child Adolesc Psychiatry 44:548-556, 2005.
22. Pennington BF, Ozonoff S: Executive functions and developmental psychopathology. J Child Psychol Psychiatry Allied-Disc 37:51-87, 1996.
23. Pierce K, Glad KS, Schreibman L: Social perception in children with autism: An attentional deficit? J Autism Dev Disord 27:265-282, 1997.
24. Piven J, Tsai GC, Nehme E, Coyle JT, Chase GA, Folstein SE: Platelet serotonin, a possible marker for familial autism. J Autism Dev Disord 21:51-59, 1991.
25. Posner MJ, Raichle ME: Networks of attention. In: Images of the Mind. Edited by Posner M and Raichle M. New York, Scientific American Library, 1994, pp 153-179.
26. RUPP, Research Units on Pediatric Psychopharmacology Autism Network: Risperidone in children with autism for serious behavioral problems. N Engl J Med 347:314-321, 2002.
27. RUPP, Research Units on Pediatric Psychopharmacology Autism Network: Risperidone treatment of autistic disorder: Longer term benefits and blinded discontinuation after six months. Am J Psychiatry 162:1361-1369, 2005.
28. Schneider W, Shiffrin RM: Controlled and automatic human information processing: Detection, search and attention. Psychol Rev 84:1-66, 1977.
29. Shiffrin RM, Schneider W: Controlled and automatic human information processing: Perceptual learning, automatic attending, and a general theory. Psychol Rev 84:127-190, 1977.
30. Stevens JP: Applied Multivariate Statistics for the Social Sciences, 4th edition. New Jersey, Lawrence Erlbaum Associates, 2002, p 197.
31. Troost PW, Lahuis BE, Steenhuis MP, Ketelaars CE, Buitelaar JK, van Engeland H, Scahill L, Minderaa RB, Hoekstra PJ: Long-term effects of risperidone in children with autism spectrum disorders: A placebo discontinuation study. J Am Acad Child Adolesc Psychiatry 44:1137-1144, 2005.
32. Turgay A, Binder C, Snyder R, Fisman S: Long-term safety and efficacy of risperidone for the treatment of disruptive behavior disorders in children with subaverage IQs. Pediatrics 110:e34, 2002.
33. Zarahn E, Rakitin B, Abela D, Flynn J, Stern Y: Positive evidence against human hippocampal involvement in working memory maintenance of familiar stimuli. Cereb Cortex 15:303-316, 2005.