La duplication du gène APP, cause de maladie d’Alzheimer associée à une importante angiopathie amyloïde

Medecine/Sciences

Volumn 22, Issue 5, 2006, Pages 468-469

  Campion, Dominique ^a   Hannequin, Didier ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN;

ALZHEIMER DISEASE; ARTICLE; GENE DUPLICATION; GENETICS; HUMAN; VASCULAR AMYLOIDOSIS;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; CEREBRAL AMYLOID ANGIOPATHY; GENE DUPLICATION; HUMANS;

EID: 33750954897     PISSN: 07670974     EISSN: 19585381     Source Type: Journal    
DOI: 10.1051/medsci/2006225468     Document Type: Article

References (4)

1. Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer’s disease: progress and problems on the road to therapeutics. Science 2002; 393: 353-6.
2. Rovelet-Lecrux A, Hannequin D, Raux G, et al. APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy. Nat Genet 2006; 38: 24-6.
3. Chartier-Harlin MC, Kachergus J, Roumier C, et al. Alpha synuclein locus duplication as a cause of familial Parkinson disease. Lancet2004; 364: 1167-9.
4. Ibanez P, Bonnet AM, Débarges B, et al. Causal relation between alpha synuclein gene duplication and familial Parkinson disease. Lancet 2004; 364: 1169-71.