Fujita-Ban QSAR analysis and CoMFA study of quinoline antagonists of immunostimulatory CpG-oligodeoxynucleotides

Bioorganic and Medicinal Chemistry

Volumn 15, Issue 1, 2007, Pages 324-332

  Paliakov, Ekaterina ^a   Henary, Maged ^a   Say, Martial ^a   Patterson, Steven E ^b   Parker, Alesia ^a   Manzel, Lori ^c   Macfarlane, Donald E ^c   Bojarski, Andrzej J ^d   Strekowski, Lucjan ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

CoMFA; CpG; QSAR; Quinolines; TLR 9

Indexed keywords

AMINE; CPG OLIGODEOXYNUCLEOTIDE; QUINOLIN 4 AMINE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; B CELL LYMPHOMA; COMPARATIVE MOLECULAR FIELD ANALYSIS; CONTROLLED STUDY; DRUG ACTIVITY; ELECTRICITY; IMMUNOSTIMULATION; IN VITRO STUDY; MOUSE; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STATISTICAL SIGNIFICANCE;

ADJUVANTS, IMMUNOLOGIC; AMINOQUINOLINES; ANIMALS; BINDING SITES; CELL LINE, TUMOR; COMPUTER SIMULATION; DRUG SCREENING ASSAYS, ANTITUMOR; LYMPHOMA, B-CELL; MICE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OLIGODEOXYRIBONUCLEOTIDES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33750943380     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.09.059     Document Type: Article

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