Misoprostol compared with prostaglandin E2 for labour induction in women at term with intact membranes and unfavourable cervix: A systematic review

BJOG: An International Journal of Obstetrics and Gynaecology

Volumn 113, Issue 12, 2006, Pages 1366-1376

  Crane, J M G ^a   Butler, B ^b   Young, D C ^b   Hannah, M E ^c  

^a MEMORIAL UNIVERSITY OF NEWFOUNDLAND   (Canada)

^b DALHOUSIE UNIVERSITY   (Canada)

^c SUNNYBROOK RESEARCH INSTITUTE   (Canada)

Author keywords

Caesarean section; Labour induced; Meta analysis; Misoprostol; Prostaglandin E2

Indexed keywords

MISOPROSTOL; PROSTAGLANDIN E2;

CESAREAN SECTION; CLINICAL TRIAL; COCHRANE LIBRARY; CONFIDENCE INTERVAL; DIARRHEA; EMBASE; HUMAN; LABOR INDUCTION; MEDICAL LITERATURE; MEDLINE; NAUSEA; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; SYSTOLE; TREATMENT OUTCOME; UTERINE CERVIX; VOMITING;

ADMINISTRATION, INTRAVAGINAL; ADMINISTRATION, ORAL; CESAREAN SECTION; DINOPROSTONE; FEMALE; HUMANS; LABOR, INDUCED; MISOPROSTOL; OXYTOCICS; PREGNANCY; RANDOMIZED CONTROLLED TRIALS; TACHYCARDIA;

EID: 33750931952     PISSN: 14700328     EISSN: 14710528     Source Type: Journal    
DOI: 10.1111/j.1471-0528.2006.01111.x     Document Type: Review

References (98)

1. Crane J, Leduc L, Farine D, Hodges S, Reid GJ, Van Aerde J. Induction of labour at term - SOGC Clinical Practice Guideline. J Obstet Gynaecol Can 2001;23:717-41.
2. Wing D. Induction of labor: indications, techniques, and complications. Up To Date Online 14.2 (www.UpToDate.com). Accessed 31 July 2006.
3. Zhang J, Yancey MK, Henderson CE. U.S. national trends in labor induction, 1989-1998. J Reprod Med 2002;47:120-4.
4. Rayburn WF, Zhang J. Rising rates of labor induction: present concerns and future strategies. Obstet Gynecol 2002;100:164-7.
5. American College of Obstetricians and Gynecologists. Induction of Labor. ACOG Practice Bulletin. Number 10. Washington, DC: American College of Obstetricians and Gynecologists, 1999.
6. Royal College of Obstetricians and Gynaecologists. Induction of Labour. Guideline. No. 9. London, UK: RCOG Press, 2001.
7. Hofmeyr GJ. Induction of labour with an unfavourable cervix. Best Pract Res Clin Obstet Gynaecol 2003;17:777-94.
8. Cammu H, Martens G, Ruyssinck G, Amy JJ. Outcome after elective labor induction in nulliparous women: a matched cohort study. Am J Obstet Gynecol 2002;186:240-4.
9. Seyb ST, Berka RJ, Socol ML, Dooley SL. Risk of cesarean delivery with elective induction of labor at term in nulliparous women. Obstet Gynecol 1999;94:600-7.
10. Luthy DA, Malmgren JA, Zingheim RW. Cesarean delivery after elective induction in nulliparous women: the physician effect. Am J Obstet Gynecol 2004;191:1511-5.
11. Crane JMG, Delaney T, Butt KD, Bennett KA, Hutchens D, Young DC. Predictors of successful labor induction with oral or vaginal misoprostol. J Mat Fetal Neonat Med 2004;15:319-23.
12. Magann EF, Chauhan SP, Mobley JA, Klausen JH, Martin JN Jr, Morrison JC. Risk factors for secondary arrest of labor among women >41 weeks' gestation with an unfavorable cervix undergoing membrane sweeping for cervical ripening. Int J Gynecol Obstet 1999;65:1-5.
13. 2 for cervical ripening. Eur J Obstet Gynecol Reprod Biol 1999;87:137-41.
14. Lange AP, Secher NJ, Westergaard JG, Skovgard I. Prelabor evaluation of inducibility. Obstet Gynecol 1982;60:137-47.
15. Watson WJ, Stevens D, Welter S, Day D. Factors predicting successful labor induction. Obstet Gynecol 1996;88:990-2.
16. Williams MC, Krammer J, O'Brien WF. The value of the cervical score in predicting successful outcome of labor induction. Obstet Gynecol 1997;90:784-9.
17. Riskin-Mashiah S, Wilkins I. Cervical ripening. Obstet Gynecol Clin North Am 1999;26:243-57.
18. Xenakis EMJ, Piper JM, Conway DL, Langer O. Induction of labor in the nineties: conquering the unfavorable cervix. Obstet Gynecol 1997;90:235-9.
19. Poma PA. Cervical ripening - a review and recommendations for clinical practice. J Reprod Med 1999;44:657-68.
20. Ramsey PS, Ramin KD, Ramin SM. Labor induction. Curr Opin Obstet Gynecol 2000;12:463-73.
21. McGuinness BJ, Trivedi AN. Maternal height as a risk factor for caesarean section due to failure to progress in labour. Aust N Z J Obstet Gynaecol 1999;39:152-4.
22. Bishop EH. Pelvic scoring for elective induction. Obstet Gynecol 1964;24:266-8.
23. Edwards RK, Richards DS. Preinduction cervical assessment. Clin Obstet Gynecol 2000;43:440-6.
24. Harrison RF, Flynn M, Craft I. Assessment of factors constituting an "inducibility profile". Obstet Gynecol 1977;49:270-4.
25. Hughey MJ, McElin TW, Bird CC. An evaluation of preinduction scoring systems. Obstet Gynecol 1976;48:635-41.
26. Arulkumaran S, Gibb DMF, TambyRaja RL, Heng SH, Ratnam SS. Failed induction of labour. Aust N Z J Obstet Gynaecol 1985;25:190-3.
27. Chandra S, Crane JMG, Hutchens D, Young DC. Transvaginal ultrasound and digital examination in predicting successful labor induction. Obstet Gynecol 2001;98:2-6.
28. Paterson-Brown S, Fisk NM, Edmonds DK, Rodeck CH. Preinduction cervical assessment by Bishop's score and transvaginal ultrasound. Eur J Obstet Gynecol Reprod Biol 1991;40:17-23.
29. Gonen R, Degani S, Ron A. Prediction of successful induction of labor: comparison of transvaginal ultrasonography and the Bishop score. Eur J Ultrasound 1998;7:183-7.
30. Sanchez-Ramos L, Kaunitz AM, Wears RL, Delke I, Gaudier FL. Misoprostol for cervical ripening and labor induction: a meta-analysis. Obstet Gynecol 1997;89:633-42.
31. Wing DA. Labor induction with misoprostol. Am J Obstet Gynecol 1999;181:339-45.
32. Hofmeyr GJ, Gulmezoglu AM, Alfirevic Z. Misoprostol for induction of labour: a systematic review. Br J Obstet Gynaecol 1999;106:798-803.
33. Sanchez-Ramos L, Kaunitz AM. Misoprostol for cervical ripening and labor induction: a systematic review of the literature. Clin Obstet Gynecol 2000;43:475-88.
34. Hofmeyr GJ, Gulmezoglu AM. Vaginal misoprostol for cervical ripening and induction of labour. Cochrane Database of Systematic Reviews. 2003, Issue 1. Art. No.: CD000941.
35. Alfirevic Z, Weeks A. Oral misoprostol for induction of labour. Cochrane Database of Systematic Reviews. 2006, Issue 2. Art. No.: CD001338.
36. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986;7:177-88.
37. Rozenberg P, Chevret S, Senat MV, Bretelle F, Paule Bonnal AP, Ville Y. A randomized trial that compared intravaginal misoprostol and dinoprostone vaginal insert in pregnancies at high risk of fetal distress. Am J Obstet Gynecol 2004;191:247-53.
38. Bolnick JM, Velazquez MD, Gonzalez JL, Rappaport VJ, McIliwain-Dunivan G, Rayburn WF. Randomized trial between two active labor management protocols in the presence of an unfavorable cervix. Am J Obstet Gynecol 2004;190:124-8.
39. Khoury AN, Zhou QP, Gorenberg DM, Nies BM, Manley GE, Mecklenburg FE. A comparison of intermittent vaginal administration of two different doses of misoprostol suppositories with continuous dinoprostone for cervical ripening and labor induction. J Matern Fetal Med 2001;10:186-92.
40. 2) for induction of labor at term. Ultrasound Obstet Gynecol 2001;18:629-35.
41. Danielian P, Porter B, Ferri N, Summers J, Templeton A. Misoprostol for induction of labour at term: a more effective agent than dinoprostone vaginal gel. Br J Obstet Gynaecol 1999;106:793-7.
42. Rowlands S, Bell R, Donath S, Morrow S, Trudinger BJ. Misoprostol versus dinoprostone for cervical priming prior to induction of labour in term pregnancy: a randomised controlled trial. Aust N Z J Obstet Gynaecol 2001;41:145-52.
43. Chang CH, Chang FM. Randomized comparison of misoprostol and dinoprostone for preinduction cervical ripening and labor induction. J Formos Med Assoc 1997;96:366-9.
44. Papanikolaou EG, Plachouras N, Drougia A, Andronikou S, Vlachou C, Stefos T, et al. Comparison of misoprostol and dinoprostone for elective induction of labor in nulliparous women at full term: a randomized prospective study. Reprod Biol Endocrinol 2004;2:70-6.
45. Meyer M, Pflum J, Howard D. Outpatient misoprostol compared with dinoprostone gel for preinduction cervical ripening: a randomized controlled trial. Obstet Gynecol 2005;105:466-72.
46. Neiger R, Greaves PC. Comparison between vaginal misoprostol and cervical dinoprostone for cervical ripening and labor induction. Tenn Med 2001;94:25-7.
47. Buser D, Mora G, Arias F. A randomized comparison between misoprostol and dinoprostone for cervical ripening and labor induction in patients with unfavorable cervices. Obstet Gynecol 1997;89:581-5.
48. 2 gel for induction of labor at term. Obstet Gynecol 1995;86:541-4.
49. 2 tablets in labour induction at term. BJOG 2004;111:436-40.
50. Bartha JL, Comino-Delgado R, Garcia-Benasach F, Martinez-del-Fresno P, Moreno-Corral LJ. Oral misoprostol and intracervical dinoprostone for cervical ripening and labor induction: a randomized comparison. Obstet Gynecol 2000;96:465-9.
51. van Gemund N, Scherjon S, leCessie S, van Leeuwen JH, van Roosmalen J, Kanhai HHH. A randomised trial comparing low dose vaginal misoprostol and dinoprostone for labor induction. BJOG 2004;111:42-9.
52. Le Roux PA, Olarogun JO, Penny J, Anthony J. Oral and vaginal misoprostol compared with dinoprostone for induction of labor. A randomized controlled trial. Obstet Gynecol 2002;99:201-5.
53. 2 to induce labor. Am J Obstet Gynecol 1997;177:1018-23.
54. Wing DA, Ortiz-Omphroy G, Paul RH. A comparison of intermittent vaginal administration of misoprostol with continuous dinoprostone for cervical ripening and labor induction. Am J Obstet Gynecol 1997;177:612-8.
55. Agarwal N, Gupta A, Kriplani A, Bhatla N, Parul N. Six hourly vaginal misoprostol versus intracervical dinoprostone for cervical ripening and labor induction. J Obstet Gynaecol Res 2003;29:147-51.
56. 2, but is it associated with more risk? Am J Obstet Gynecol 1999;180:1543-50.
57. 2 gel for preinduction cervical ripening and labor induction. Am J Obstet Gynecol 1995;172:1804-10.
58. Wing DA, Rahall A, Jones MM, Goodwin TM, Paul RH. Misoprostol: an effective agent for cervical ripening and labor induction. Am J Obstet Gynecol 1995;172:1811-6.
59. Dallenbach P, Boulvain M, Viardot C, Irion O. Oral misoprostol or vaginal dinoprostone for labor induction: a randomized controlled trial. Am J Obstet Gynecol 2003;188:162-7.
60. Hofmeyr GJ, Alfirevic Z, Matonhodze B, Brocklehurst P, Campbell E, Nikodem VC. Titrated oral misoprostol solution for induction of labour: a multi-centre randomised trial. BJOG 2001;108:952-9.
61. 2 for preinduction cervical ripening. A randomized trial. J Reprod Med 2001;46:641-6.
62. Ramsey PS, Harris DY, Ogburn PL Jr, Heise RH, Magtibay PM, Ramin KD. Comparative efficacy and cost of the prostaglandin analogs dinoprostone and misoprostol as labor preinduction agents. Am J Obstet Gynecol 2003;188:560-5.
63. 2 for induction of labor on the incidence of pathological CTG tracing: a randomized trial. Eur J Obstet Gynecol Reprod Biol 2004;116:34-8.
64. 2 pessary. Cent Afr J Med 2002;48:123-8.
65. Garry D, Figueroa R, Kalish RB, Catalano CJ, Maulik D. Randomized controlled trial of vaginal misoprostol versus dinoprostone vaginal insert for labor induction. J Matern Fetal Neonatal Med 2003;13:254-9.
66. Lokugamage AU, Forsyth SF, Sullivan KR, El Rafaey H, Rodeck CH. Dinoprostone versus misoprostol: a randomized study of nulliparous women undergoing induction of labor. Acta Obstet Gynecol Scand 2003;82:133-7.
67. Urban R, Lemancewicz A, Urban J, Skotnicki MZ, Kretowska M. Misoprostol and dinoprostone therapy for labor induction: a doppler comparison of uterine and fetal hemodynamic effects. Eur J Obstet Gynecol Reprod Biol 2003;106:20-4.
68. Rozenberg P, Chevret S, Goffinet F, Durand-Zaleski I, Ville Y, Vayssiere C, et al. Induction of labour with a viable infant: a randomised clinical trial comparing intravaginal misoprostol and intravaginal dinoprostone. BJOG 2001;108:1255-62.
69. 2 alpha gel. Int J Gynecol Obstet 2002;76:127-33.
70. Leszczynska-Gorzelak B, Laskowska M, Oleszczuk J. Comparative analysis of the effectiveness of misoprostol and prostaglandin E(2) in the preinduction and induction of labor. Med Sci Monit 2001;7:1023-8.
71. Charoenkul S, Sripramote M. A randomized comparison of one single dose of vaginal 50 microg misoprostol with 3 mg dinoprostone in pre-induction cervical ripening. J Med Assoc Thai 2000;83:1026-34.
72. Clark S, Blum J, Blanchard K, Galvao L, Fletcher H, Winikoff B. Misoprostol use in obstetrics and gynecology in Brazil, Jamaica, and the United States. Int J Gynecol Obstet 2002;76:65-74.
73. Magtibay PM, Ramin KD, Harris DY, Ramsey PS, Ogburn PL Jr. Misoprostol as a labor induction agent. J Matern Fetal Med 1998;7:15-8.
74. 1 misoprostol compared with dinoprostone vaginal insert: a randomized trial. Obstet Gynecol 1998;91:401-5.
75. Ozgur K, Kizilates A, Uner M, Erman O, Trak B. Induction of labor with intravaginal misoprostol versus intracervical dinoprostone. Arch Gynecol Obstet 1997;261:9-13.
76. Gottschall DS, Borgida AF, Mihalek JJ, Sauer F, Rodis JF. A randomized clinical trial comparing misoprostol with prostaglandin E2 gel for preinduction cervical ripening. Am J Obstet Gynecol 1997;177:1067-70.
77. Lee HY. A randomised double-blind study of vaginal misoprostol vs dinoprostone for cervical ripening and labour induction in prolonged pregnancy. Singapore Med J 1997;38:292-4.
78. Herabutya Y, O-Prasertsawat P, Pokpirom J. A comparison of intravaginal misoprostol and intracervical prostaglandin E2 gel for ripening of unfavorable cervix and labor induction. J Obstet Gynaecol Res 1997;23:369-74.
79. Windrim R, Bennett K, Mundle W, Young DC. Oral administration of misoprostol for labor induction: a randomized controlled trial. Obstet Gynecol 1997;89:392-7.
80. Kadanali S, Kucukozkan T, Zor N, Kumtepe Y. Comparison of labor induction with misoprostol vs. oxytocin/prostaglandin E2 in term pregnancy. Int J Gynecol Obstet 1996;55:99-104.
81. Mundle WR, Young DC. Vaginal misoprostol for induction of labor: a randomized controlled trial. Obstet Gynecol 1996;88:521-5.
82. Chuck FJ, Huffaker BJ. Labor induction with intravaginal misoprostol versus intracervical prostaglandin E2 gel (Prepidil gel): randomized comparison. Am J Obstet Gynecol 1995;173:1137-42.
83. Fletcher H, Mitchell S, Frederick J, Simeon D, Brown D. Intravaginal misoprostol versus dinoprostone as cervical ripening and labor-inducing agents. Obstet Gynecol 1994;83:244-7.
84. Zeteroglu S, Sahin HG, Sahin HA. Induction of labor with misoprostol in grand multiparous patients. Int J Gynecol Obstet 2004;87:155-6.
85. Raio L, Ghezzi F, Di Naro E, Bruhwiler H, Luscher KP. Shorter delivery time after induction with misoprostol. Z Geburtshilfe Neonatol 2001;205:147-51.
86. Saggaf A, Rouzi AA, Facharzt BR, Alshehry S, Yamani T, Abduljabbar H. Misoprostol preinduction cervical ripening and induction of labor: a randomized controlled trial. Saudi J Obstet Gynecol 2001;1:89-93.
87. Gregson S, Waterstone M, Norman I, Murrells T. A randomised controlled trial comparing low dose vaginal misoprostol and dinoprostone vaginal gel for inducing labour at term. BJOG 2005;112:438-44.
88. Langenegger EJ, Odendaal HJ, Grove D. Oral misoprostol versus intracervical dinoprostone for induction of labor. Int J Gynecol Obstet 2005;88:242-8.
89. Belfrage P, Smedvig E, Gjessing L, Eggebo TM, Okland I. A randomized prospective study of misoprostol and dinoprostone for induction of labor. Acta Obstet Gynecol Scand 2000;79:1065-8.
90. Leszcynska-Gorzelak B, Laskowska M, Oleszczuk J. Using of misoprostol for preinduction and induction of labor in term pregnancy. Ginekol Pol 1999;70:881-9.
91. O'Flaherty L. Oral misoprostol and intracervical dinoprostone for cervical ripening and labor induction: a randomized comparison. J Midwifery Womens Health 2001;46:203-4.
92. Sanchez-Ramos L, Kaunitz AM. Oral administration of misoprostol for labor induction: a randomized controlled trial. Obstet Gynecol 1997;90:153-4.
93. Howarth GR, Pistorius L, Mantel G, Funk M, Pattinson RC. Induction of labour at term - misoprostol, efficacy, economics and ethics. S Afr Med J 1996;86:1174-6.
94. Ramsey PS, Harris DY, Ogburn PL, Heise RH, Magtibay PM, Ramin KD. Comparative cost analysis of prostaglandin analogues dinoprostone and misoprostol as labor preinduction agents. Prim Care Update Ob Gyn 1998;5:182.
95. Meyer M, Pflum J. Outpatient administration of misoprostol decreases induction time. Am J Obstet Gynecol 2002;187:S167.
96. Tabor B, Anderson J, Stettler B, Wetwiska N, Howard T. Misoprostol versus prostaglandin E2 gel for cervical ripening. Am J Obstet Gynecol 1995;172:425.
97. Assmann SF, Pocock SJ, Enos LE, Kasten LE. Subgroup analysis and other (mis)uses of baseline data in clinical trials. Lancet 2000;355:1064-9.
98. Williams MC, Tsibris JCM, Davis G, Baiano J, O'Brien WF. Dose variation that is associated with approximated one-quarter tablet doses of misoprostol. Am J Obstet Gynecol 2002;187:615-9.