DNA microarray analysis of pulmonary fibrosis three months after exposure to paraquat in rats

Journal of Toxicological Sciences

Volumn 31, Issue 4, 2006, Pages 345-355

  Satomi, Yoshihide ^a,b   Tsuchiya, Wakana ^a   Miura, Daishiro ^c   Kasahara, Yoshinori ^a   Akahori, Fumiaki ^b  

^a TEIJIN PHARMA LIMITED   (Japan)

^b AZABU UNIVERSITY   (Japan)

^c NONE

Author keywords

DNA microarray; Gene expression profiling; Paraquat; Pulmonary fibrosis

Indexed keywords

ADENOSINE A2 RECEPTOR; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); AMILORIDE; CATION CHANNEL; COFILIN; COLLAGEN; COLONY STIMULATING FACTOR RECEPTOR; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; LIM PROTEIN; PARAQUAT; POTASSIUM CHANNEL; PROTEIN KINASE; PROTEIN KINASE 1; PROTEIN TYROSINE PHOSPHATASE SHP 1; SIGNALING LYMPHOCYTE ACTIVATION MOLECULE ASSOCIATED PROTEIN; SODIUM CHANNEL; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL;

ACTIN FILAMENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; CYTOSKELETON; DNA MICROARRAY; ELECTROLYTE BALANCE; FLUID BALANCE; GENE EXPRESSION; LUNG EDEMA; LUNG FIBROSIS; LUNG INJURY; LUNG WEIGHT; MACROPHAGE ACTIVATION; MALE; MONOCYTE; NONHUMAN; RAT; WOUND HEALING;

EID: 33750906569     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.31.345     Document Type: Article

References (27)

1. Akahori, F. and Oehme, F.W. (1983): Inhibition of collagen synthesis as treatment for paraquat poisoning. Vet. Hum. Toxicol., 25, 321-327.
2. nd and Kleinerman, J. (1971): Paraquat in the rabbit. Br. J. Ind. Med., 28, 67-71.
3. Dada, L.A. and Sznajder, J.I. (2003): Mechanisms of pulmonary edema clearance during acute hypoxemic respiratory failure: Role of the Na,K-ATPase. Crit Care Med., 31, 248-252.
4. Dubaybo, B.A. and Thet, L.A. (1986): Changes in lung tissue and lavage fibronectin after paraquat injury in rats. Res. Commun. Chem. Pathol. Pharmacol., 51, 211-220.
5. + channels in lung alveolar type II epithelial cells. Proc. Am. Thorac. Soc., 1, 10-16.
6. Egli, M., Duplain, H., Lepori, M., Cook, S., Nicod, P., Hummler, E., Sartori, C. and Scherrer, U. (2004): Defective respiratory amiloride-sensitive sodium transport predisposes to pulmonary oedema and delays its resolution in mice. J. Physiol., 560, 857-865.
7. Fuxe, K., Ferre, S., Canals, M., Torvinen, M., Terasmaa, A., Marcellino, D., Goldberg, S.R., Staines, W., Jacobsen, K.X., Lluis, C., Woods, A.S., Agnati, L.F. and Franco, R. (2005): Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function. J. Mol. Neurosci., 26, 209-220.
8. Hampson, E.C.G.M. and Pond, S.M. (1988): Ultrastructure of canine lung during the proliferative phase of paraquat toxicity. Br. J. Exp. Pathol., 69, 57-68.
9. Hasko, G., Xu, D.Z., Lu, Q., Nemeth, Z.H., Jabush, J., Berezina, T.L., Zaets, S.B., Csoka, B. and Deitch, E.A. (2006): Adenosine A2A receptor activation reduces lung injury in trauma/hemorrhagic shock. Crit. Care Med., 34, 1119-1125.
10. Helms, M.N., Chen, X.J., Ramosevac, S., Eaton, D.C. and Jain, L. (2006): Dopamine regulation of amiloride-sensitive sodium channels in lung cells. Am. J. Physiol. Lung Cell. Mol. Physiol., 290, L710-L722.
11. Helms, M.N., Self, J., Bao, H.F., Job, L.C., Jain, L. and Eaton, D.C. (2006): Dopamine Activates Amiloride-Sensitive Sodium Channels in Alveolar Type 1 Cells in a Lung Slice Preparation. Am. J. Physiol. Lung Cell. Mol. Physiol., May 5; [Epub ahead of print].
12. Hotulainen, P., Paunola, E., Vartiainen, M.K. and Lappalainen, P. (2005): Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells. Mol. Biol. Cell, 16, 649-664.
13. Inagaki, K., Yamao, T., Noguchi, T., Matozaki, T., Fukunaga, K., Takada, T., Hosooka, T., Akira, S. and Kasuga, M. (2000): SHPS-1 regulates integrin-mediated cytoskeletal reorganization and cell motility. EMBO J., 19, 6721-6731.
14. Jamall, I.S., Finelli, V.N. and Que Hee, S.S. (1981): A simple method to determine nanogram levels of 4-hydroxyproline in biological tissues. Anal. Biochem., 112, 70-75.
15. Kemp, P.J. and Kim, K.J. (2004): Spectrum of ion channels in alveolar epithelial cells: Implications for alveolar fluid balance. Am. J. Physiol. Lung Cell. Mol. Physiol., 287, 460-464.
16. Kim, D.Y., Ingano, L.A., Carey, B.W., Pettingell, W.H. and Kovacs, D.M. (2005): Presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-subunit regulates cell adhesion and migration. J. Bio.l Chem., 280, 23251-23261. Erratum in: J. Biol. Chem., 280, 29988.
17. Kudlacek, O., Just, H., Korkhov, V.M., Vartian, N., Klinger, M., Pankevych, H., Yang, Q., Nanoff, C., Freissmuth, M. and Boehm, S. (2003): The human D2 dopamine receptor synergizes with the A2A adenosine receptor to stimulate adenylyl cyclase in PC12 cells. Neuropsychopharmacology, 28, 1317-1327.
18. Maile, L.A., Badley-Clarke, J. and Clemmons, D.R. (2003): The association between integrin-associated protein and SHPS-1 regulates insulin-like growth factor-I receptor signaling in vascular smooth muscle cells. Mol. Biol. Cell, 14, 3519-3528.
19. Matalon, S., Lazrak, A., Jain, L. and Eaton, D.C. (2002): Invited review: Biophysical properties of sodium channels in lung alveolar epithelial cells. J. Appl. Physiol., 93, 1852-1859.
20. Murai-Takebe, R., Noguchi, T., Ogura, T., Mikami, T., Yanagi, K., Inagaki, K., Ohnishi, H., Matozaki, T. and Kasuga, M. (2004): Ubiquitination-mediated regulation of biosynthesis of the adhesion receptor SHPS-1 in response to endoplasmic reticulum stress. J. Biol. Chem., 279, 11616-11625.
21. Murray, R.E. and Gibson, J.E. (1972): A comparative study of paraquat intoxication rats, guinea pigs, and monkeys. Exp. Mol. Pathol., 17, 317-325.
22. O'Grady, S.M. and Lee, S.Y. (2003): Chloride and potassium channel function in alveolar epithelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol., 284, 689-700.
23. Prochniewicz, E., Janson, N., Thomas, D.D. and De la Cruz, E.M. (2005): Cofilin increases the torsional flexibility and dynamics of actin filaments. J. Mol. Biol., 353, 990-1000.
24. Salmi, P., Chergui, K. and Fredholm, B.B. (2005): Adenosine-dopamine interactions revealed in knockout mice. J. Mol. Neurosci., 26, 239-244.
25. Satomi, Y., Tsuchiya, W., Mihara, K., Ota, M., Kasahara, Y. and Akahori, F. (2004): Gene expression analysis of the lung following paraquat administration in rats using DNA microarray. J. Toxicol. Sci., 29, 91-100.
26. Toner, P.G., Vetters, J.M., Spilg, W.G.S. and Harland, W.A. (1970): Fine structure of the lung lesion in a case of paraquat poisoning. J. Pathol., 102, 182-185.
27. Willis, D., Li, K.W., Zheng, J.Q., Chang, J.H., Smit, A., Kelly, T., Merianda, T.T., Sylvester, J., van Minnen, J. and Twiss, J.L. (2005): Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons. J. Neurosci., 25, 778-791.