Pathognomonic genetic expression profile within peripheral blood mononuclear cells of rheumatic heart disease patients

Molecular and Cellular Biochemistry

Volumn 291, Issue 1-2, 2006, Pages 213-217

  Baba, M Iqbal ^a   Kaul, Deepak ^a   Grover, Anil ^a  

^a POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CD36 ANTIGEN; CHEMOKINE RECEPTOR CXCR1; GAMMA INTERFERON; INTERLEUKIN 8; MESSENGER RNA; TRANSCRIPTOME;

ADULT; ARTICLE; AUTOIMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; GENE EXPRESSION; GENETIC CODE; HUMAN; MALE; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATIC HEART DISEASE; UPREGULATION;

ADULT; CYTOKINES; ELECTROPHORESIS, AGAR GEL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; LEUKOCYTES, MONONUCLEAR; MIDDLE AGED; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; RHEUMATIC HEART DISEASE; RNA, MESSENGER;

EID: 33750903388     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-006-9197-4     Document Type: Article

References (28)

1. Guilherme L, Cunha-Neto E, Coelho V, Snitcowsky R, Pomerantzeff PMA, Assis RV, Pedra F, Neumann J, Goldberg A, Patarroyo ME, Pillegi F, Kalil J: Human-infiltrating T cell clones from rheumatic heart disease patients recognize both streptococcal and cardiac proteins. Circulation 92: 415-420, 1995
2. Roberts S, Kosanke S, Dunn ST, Jankelow D, Duran CMG, Cunningham MW: Pathogenic mechanisms in rheumatic carditis: Focus on valvular endothelium. J Infect Dis 183: 507-511, 2001
3. Kaul D: Cholesterol-receptor mediated genomics in health and disease. Trends Mol Med 9: 442-449, 2003
4. Delerive P, Fruchart JC, Staels B: Peroxisome proliferator-activated receptors in inflammation control. J Endocrinol 169: 453-459, 2001
5. Feghali CA, Wright TM: Cytokines in acute and chronic inflammation. Frontiers Biosci 2: D12-26, 1997
6. Hafez M, EL-Morsy Z, EL-Shennawy F, Hawas S, Sheishaa A, Abo-EL-Kheir M, Shokeir M, Al-Marsafawy H, EL-Baz R, Atia G: Susceptibility to over production of cytokines in acute rheumatic carditis and their role in the pathogenesis. J Med Sci 2: 65-73, 2002
7. Joseph SB, Castrillo A, Laffitte BA, Mangelsdorf DJ, Tontonoz P: Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat Med 13: 213-219, 2003
8. Nanki T, Imai T, Nagasaki K, Urasaki Y, Nonomura Y, Taniguchi K, Hayashida K, Hasegawa K, Yoshie O, Miyasaka N: Migration of CX3CR1-positive T cells producing type 1 cytokines and cytotoxic molecules into the synovium of patients with rheumatoid arthritis. Arthritis Rheum 46: 2878-2883, 2002
9. Yesner LM, Huh H, Pearce SF, Silverstein RL: Regulation of monocyte CD36 and thrombospondin-1 expression by soluble mediators. Arterioscler Thromb Vasc Biol 16: 1019-1025, 1996
10. Dajani AS, Ayoub E, Bierman FZ, Bisno AL, Deny FW, Durack DT, Ferrieri P, Freed M, Gerber M, Kaplan EL, Karchmer AW, Markowitz M, Rahimtoola S, Shulman S, Stollerman G, Takahashi M, Taranta A, Tauber KA, Wilson W: 1993 Guidelines for diagnosis of rheumatic fever: Jones criteria, updated. Circulation 87: 302-307, 1992
11. Boyum A: Ficoll-Hypaque method for separating mononuclear cells and granulocytes from human blood. Scand J Clin Lab Invest 77: 57-62 [Suppl], 1968
12. Chomczynski P, Sacchi N: Single step method of RNA isolation by acid guanidium thiocyanate phenol chloroform extraction. Anal Biochem 162: 156-159, 1987
13. Marx N, Schönbeck U, Lazar MA, Libby P, Plutzky J: Peroxisome proliferator-activated receptor γ activators inhibit gene expression and migration in human vascular smooth muscle cells. Circ Res 83: 1097-1103, 1998
14. Auboeuf D, Reiusset J, Fajas L, Vallier P, Frering V, Riou JP, Staels B, Auwerx J, Laville M, Vidal H: Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor α in humans: No alteration in adipose tissue of obese and NIDDM patients. Diabetes 46: 1319-1327, 1997
15. 1 downregulates CD36 and scavenger receptor A but upregulates LOX-1 in human macrophages. Am J Physiol Heart Circ Physiol 278: H1042-H1048, 2000
16. Glare EM, Divjak M, Bailey MJ, Walters EH: The usefulness of competitive PCR: Airway gene expression of IL-5, IL-4, IL-4d2 and IFN-gamma in asthma. Thorax 26: 541-548, 2001
17. Higa S, Hirano T, Kotani M, Matsumoto M, Fujita A, Suemera M, Kawase I, Tanaka T: Fistein, a flavonol, inhibits TH2-type cytokine production by activated human basophils. J Allergy Clin Immunol 111: 1299-1306, 2003
18. Barlic J, Sechler JM, Murphy PM: IL-15 and IL-12 oppositely regulate expression of the chemokine receptor CX3CR1. Blood 102: 3494-3503, 2003
19. Xu D, Gruber A, Peterson C, Pisa P: Telomerase activity and the expression of telomerase components in acute myelogenous leukemia. Br J Haematol 102: 1367-1375, 1998
20. Adorni L, Cytokine-based immunointervention in the treatment of autoimmune diseases. Clin Exp Immunol 132: 185-192, 2003
21. Chinetti G, Fruchart JC, Staels B: Role of the PPAR family of nuclearreceptors in the regulation of metabolic and cardiovascular homeostasis: New approaches to therapy. Curr Opin Pharmacol 5: 177-183, 2005
22. Corcoran L, Vremec D, Febbraio M, Baldwin T, Handman E: Differential regulation of CD36 expression in antigen presenting cells: Oct-2 dependence in lymphocytes but not dendritic cells or macrophages. International Immunol 14: 1099-1104, 2003
23. Feng JJ, Pearce SFA, Silverstein RL, Gotto Jr AM, Hajjar DP, Nicholson AC: Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPARγ. J Lipid Res 41: 686-696, 2000
24. Nakagawa T, Nozaki S, Nishida M, Yakub JM, Tomiyama Y, Nakata A, Matsumuto K, Funahashi T, Kameda-Takemura K, Kurata Y, Yamashita S, Matsuzawa Y: Oxidized LDL increases and interferon-gamma decreases expression of CD36 in human monocyte derived macrophages. Arterioscler Thromb Vasc Biol 18: 1350-1357, 1998
25. Fae KC, Oshiro SE, Toubert A, Charron D, Kalil J, Guilherme L: How an autoimmune reaction triggered by molecular mimicry between streptocopccal M protein and cardiac tissue proteins leads to heart lesions in rheumatic heart disease. J Autoimmun 24: 101-109, 2005
26. Guilherme L, Cunha-Neto E, Tanaka AC, Dulphy N, Toubert A, Kalil J: Heart directed autoimmunity: The case of rheumatic fever. J Autoimmun 16: 363-367, 2001
27. Guilherme L, Cury P, Demarchi Lea MF, Coelho V, Abel L, Lopez Ana P, Oshiro SE, Aliotti S, Cunha-Neto E, Pomerantzeff PMA, Tanaka AC, Kalil J: Rheumatic Heart Disease - Proinflammatory cytokines play a role in the progression and maintenancr of valvular lesions. Am J Pathol 165: 1583-1591, 2004
28. Miller LC, Gray ED, Mansour M, Abdin ZH, Kamel R, Zaher S, Regelmann WE: Cytokines and immunoglobulin in rheumatic heart disease: Production by blood and tonsillar mononuclear cells. J Rheumatol 16: 1436-1442, 1989