Incomplete global cerebral ischemia alters platelet biology in neonatal and adult sheep

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 274, Issue 4 43-4, 1998, Pages

  Littleton Kearney, Marguerite T ^a   Hurn, Patricia D ^a   Kickler, Thomas S ^a   Traystman, Richard J ^a  

^a JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Chronological age; Platelet aggregation; Platelet entrapment

Indexed keywords

ADENOSINE TRIPHOSPHATE; BETA THROMBOGLOBULIN; CALCIUM;

AGE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL GAS; ARTICLE; BRAIN BLOOD FLOW; BRAIN REGION; CONTROLLED STUDY; HEMATOCRIT; LAMB; NEWBORN; NONHUMAN; PRIORITY JOURNAL; REPERFUSION; SHEEP; SPLEEN; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; TRANSIENT ISCHEMIC ATTACK;

EID: 33750879243     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1998.274.4.h1293     Document Type: Article

References (42)

1. Borel, C. O., J. E. Backofen, R. C. Koehler, M. D. Jones, Jr., and R. J. Traystman. Cerebral blood flow autoregulation during intracranial hypertension in hypoxic lambs. Am. J. Physiol. 253 (Heart Circ. Physiol. 22): H1342-H1348, 1987.
2. Cardinal, P. C., and R. Flower. The electronic aggregometer: a novel device for assessing platelet behavior in whole blood. J. Pharmacol. Methods 3: 135-158, 1980.
3. Corby, D. G., and T. F. Zuck. Newborn platelet dysfunction: a storage pool and release defect. Thromb. Haemost. 36: 200-207, 1976.
4. Corby, D. G., and T. P. O'Barr. Decreased alpha-adrenergic receptors in newborn platelets: cause of abnormal response to epinephrine. Dev. Pharmacol. Ther. 2: 215-225, 1981.
5. Dewanjee, M. K., S. A. Rao, and P. Didisheim. Indium-111 tropolone, a new high-affinity platelet label: preparation and evaluation of labeling parameters. J. Nucl. Med. 22: 981-987, 1981.
6. 111In-labeled platelet study. Stroke 24: 1534-1540, 1993.
7. Dougherty, J. H., D. E. Levy, and B. B. Weksler. Platelet activation in acute cerebral ischemia. Serial measurements of platelet function in cerebrovascular disease. Lancet 1: 821-824, 1977.
8. Dougherty, J. H., D. E. Levy, and B. B. Weksler. Experimental cerebral ischemia produces platelet aggregates. Neurology 29: 1460-1465, 1979.
9. Elgjo, R. F., and T. Hovig. Ultrastructural studies of platelet "activation" and aggregation in normal spleen from different species. Scand. J. Haematol. 9: 587-602, 1972.
10. Farkkila, M. A., V. Rasi, R. S. Tilvis, E. Ikkala, L. Viinikka, O. Ylikorkala, A. M. Farkkila, and T. A. Miettinen. Low platelet arachidonic acid in young patients with brain infarction. Thromb. Res. 48: 721-727, 1987.
11. Fisher, M., and R. Francis. Altered coagulation in cerebral ischemia: platelet, thrombin, and plasmin activity. Arch. Neurol. 47: 1075-1079, 1990.
12. Freedman, R. M., D. Johnston, M. J. Mahoney, and H. A. Pearson. Development of splenic reticuloendothelial dysfunction in neonates. J. Pediatr. 96: 466-468, 1980.
13. Furlow, T. W., and J. M. Hallenbeck. Indomethacin prevents impaired perfusion of the dog's brain after global ischemia. Stroke 9: 591-594, 1978.
14. Galante, A., A. Pietroiusti, M. Silvestrini, P. Stanzione, B. Domenici, and G. Bernardi. Leukocyte and platelet aggregation in patients with ischemic stroke: a case-control study. Eur. Neurol. 33: 442-445, 1993.
15. a) dependent homotypic and heterotypic cell-cell interactions. J. Clin. Invest. 88: 1128-1134, 1991.
16. Grau, A. J., R. Sigmund, and W. Hacke. Modification of platelet aggregation by leukocytes in acute ischemic stroke. Stroke 25: 2149-2152, 1994.
17. Gross, C. E., D. B. Howard, R. H. Dooley, S. J. Raymond, S. Fuller, and M. M. Bednar. TGF-β1 post-treatment in a rabbit model of cerebral ischaemia. Neurol. Res. 16: 465-470, 1994.
18. Heymann, M. A., B. D. Payne, J. I. E. Hoffman, and A. M. Rudolph. Blood flow measurements with radionuclide-labeled particles. Prog. Cardiovasc. Dis. 20: 55-79, 1997.
19. Holmsen, H. Platelet secretion and energy metabolism. In: Hemostasis and Thrombosis: Basic Principles and Clinical Practice, edited by R. W. Coleman, J. Hirsh, V. J. Marder, and E. W. Salzman. Philadelphia, PA: Lippincott, 1994, p. 527.
20. Hossmann, V., K. A. Hossmann, and S. Takagi. Effect of intravascular platelet aggregation on blood recirculation following prolonged ischemia of the cat brain. J. Neurol. 222: 159-170, 1980.
21. Hurn, P. D., R. C. Koehler, S. E. Norris, K. K. Blizzard, and R. J. Traystman. Dependence of cerebral energy phosphate and evoked potential recovery on end-ischemic pH. Am. J. Physiol. 260 (Heart Circ. Physiol. 29): H532-H541, 1991.
22. Iwamoto, T., H. Kubo, and M. Takasaki. Platelet activation in the cerebral circulation in different subtypes of ischemic stroke and Binswanger's disease. Stroke 26: 52-56, 1995.
23. Jafar, J. J., R. Menoti, H. Feinberg, G. LeBreton, and R. Crowell. Selective platelet deposition during focal cerebral ischemia in cats. Stroke 20: 664-667, 1989.
24. Joseph, R., G. D'Andrea, S. B. Oster, and K. M. A. Welch. Whole blood platelet function in acute ischemic stroke. Stroke 20: 38-44, 1988.
25. Joseph, R., E. Han, C. Tsering, S. Grunfeld, and K. M. A. Welch. Platelet activity and stroke severity. J. Neurol. Sci. 108: 1-6, 1992.
26. Joseph, R., J. M. Riddle, K. M. A. Welch, and G. D'Andrea. Platelet ultrastructure and secretion in acute ischemic stroke. Stroke 20: 1316-1319, 1989.
27. Joseph, R., K. M. A. Welch, S. Grunfield, S. B. Oster, and G. D'Andrea. Baseline and activated cytoplasmic ionized calcium in acute ischemic stroke. Stroke 19: 1234-1238, 1988.
28. Joseph, R., K. M. A. Welch, S. B. Oster, S. Grunfeld, and G. D'Andrea. A plasmic factor may cause platelet activation in acute stroke. Circ. Res. 65: 1679-1687, 1989.
29. Kaplan, J. E., and T. M. Saba. Platelet removal from the circulation by liver and spleen. Am. J. Physiol. 235 (Heart Circ. Physiol. 4): H314-H320, 1978.
30. Kearney, M. L., J. E. Backofen, R. C. Koehler, M. D. Jones, Jr., and R. C. Traystman. Effect of hypoxemia on the cardiovascular response to intracranial hypertension in postnatal lambs. Am. J. Physiol. 265 (Heart Circ. Physiol. 34): H1557-H1563, 1993.
31. Koudstaal, P. J., G. Ciabattoni, J. van Gijn, K. Nieuwenhuis, P. G. de Groot, J. J. Sixma, and C. Patrone. Increased thromboxane biosynthesis in patients with acute cerebral ischemia. Stroke 24: 219-223, 1993.
32. Lee, Y. J., W. Jy, L. L. Horstman, J. Janania, Y. Reyes, R. E. Kelley, and Y. S. Ahn. Elevated platelet microparticles in transient ischemic attacks, lacunar infarcts, and multiinfarct dementias. Thromb. Res. 72: 295-304, 1993.
33. Mull, M. M., and W. E. Hathaway. Altered platelet function in newborns. Pediatr. Res. 4: 229-237, 1970.
34. Obrenovitch, T. P., and J. M. Hallenbeck. Platelet accumulation in regions of low blood flow during the postischemic period. Stroke 16: 224-233, 1985.
35. Olah, L., M. Misz, D. Bereczki, I. Fekete, J. E. Bordanne, and E. I. Takacs. Low doses of acetylsalicylic acid effectively inhibits thrombocyte aggregation after ischemic stroke. Orv. Hetil. 137: 455-459, 1996.
36. O'Malley, T., P. Langhorne, R. A. Elton, and C. Stewart. Platelet size in stroke patients. Stroke 26: 995-999, 1995.
37. Rajasekhar, D., A. S. Kestin, F. J. Bednarek, P. A. Ellis, M. R. Barnard, and A. D. Michelson. Neonatal platelets are less reactive than adult platelets to physiological agonists in whole blood. Thromb. Haemost. 72: 957-963, 1994.
38. Satoh, S., Y. Suzuki, T. Harada, I. Ikegaki, T. Asano, M. Shubuya, K. Sugita, and A. Saito. The role of platelets in the development of cerebral vasospasm. Brain Res. Bull. 27: 663-668, 1991.
39. Shah, A. B., N. Beamer, and B. M. Coull. Enhanced in vivo platelet activation in subtypes of ischemic stroke. Stroke 16: 643-647, 1985.
40. Tohgi, H., H. Suzuki, K. Tamura, and B. Kimura. Platelet volume, aggregation, and adenosine triphosphate release in cerebral thrombosis. Stroke 22: 17-21, 191.
41. Ware, J. A., and D. D. Heistad. Platelet-endothelium interactions. N. Engl. J. Med. 328: 628-635, 1993.
42. Wencel-Drake, J. D., C. Boudignon-Proudhon, M. G. Dieter, A. B. Criss, and L. V. Parise. Internalization of bound fibrinogen modulates platelet aggregation. Blood 87: 602-612, 1996.