Internalization of bound fibrinogen modulates platelet aggregation

Blood

Volumn 87, Issue 2, 1996, Pages 602-612

  Wencel Drake, June D ^a   Boudignon Proudhon, Christel ^b   Dieter, Michael G ^b   Criss, Anne B ^b   Parise, Leslie V ^b  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOGEN; FIBRINOGEN RECEPTOR; GLYCOPROTEIN IIB; GLYCOPROTEIN IIIA;

ARTICLE; BLEEDING; CONTROLLED STUDY; FIBRIN CLOT; HEMOSTASIS; HUMAN; HUMAN CELL; INTERNALIZATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION;

EID: 0030044509     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v87.2.602.bloodjournal872602     Document Type: Article

References (59)

1. Smyth SS, Joneckis CC, Parise LV: Regulation of vascular integrins. Blood 81:2827, 1993
2. Van Willigen G, Akkerman J-WN: Protein kinase C and cyclic AMP regulate reversible exposure of binding sites for fibrinogen on the GPIIb-IIIa complex of human platelets. Biochem J 273:115, 1991
3. O'Brien JR: Variability in the aggregation of human platelets by epinephrine, Nature 202:1188, 1964
4. Cooper B, Handin RH, Young LH, Alexander RW: Agonist regulation of the human platelet alpha-adrenergic receptor. Nature 274:703, 1978
5. 2-adrenoreceptor affinity for agonist by endogenous and exogenous catecholamines. J Clin Invest 72:1498, 1983
6. 2+ mobilization and fibrinogen binding of platelets refractory to adenosine diphosphate stimulation. J Lab Clin Med 106:111, 1985
7. 2-adrenoreceptor or receptor coupling to adenylate cyclase. Mol Pharmacol 29:1, 1986
8. McGowan EB, Detwiler TC: Characterization of the thrombin-induced desensitization of platelet activation by thrombin. Thromb Res 31:297, 1983
9. Shattil SJ, Motulsky HJ, Insel PA, Flaherty L, Brass LF: Expression of fibrinogen receptors during activation and subsequent desensitization of human platelets by epinephrine. Blood 68:1224, 1986
10. Marguerie GA, Plow EF: Interaction of fibrinogen with its platelet receptor: Kinetics and effect of pH and temperature. Biochemistry 20:1074, 1981
11. Peerschke EIB: Decreased accessibility of platelet-bound fibrinogen to antibody and enzyme probes. Blood 74:682, 1989
12. Peerschke EIB: Adhesive protein expression on thrombin-stimulated platelets: Time-dependent modulation of anti-fibrinogen, -fibronectin, and -von Willebrand factor antibody binding. Blood 79:948, 1992
13. Peerschke EIB: Recognition of platelet-associated fibrinogen by polyclonal antibodies: Correlation with platelet aggregation. Blood 79:2028, 1992
14. Kazal LA, Amsel S, Miller OP, Tocantins LM: The preparation and some properties of fibrinogen precipitated from human plasma by glycine. Proc Soc Exp Biol Med 113:989, 1963
15. 3) in isolated platelet membranes. Biochem J 292:749, 1993
16. 3 integrins: Comparison of GP IIb-IIIa and the vitronectin receptor individually expressed in human melanoma cells J Cell Biol 113:451, 1991
17. 3 by applaggin: Evidence for internalization and cycling of a platelet integrin. Blood 81:62, 1993
18. Handagama PJ, Shuman MA, Bainton DF. Incorporation of intravenously injected albumin, immunoglobulin G, and fibrinogen in guinea pig megakaryocyte granules. J Clin Invest 84:73, 1989
19. Newman PJ, Allen RW, Kahn RA, Kunicki TJ: Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody AP-3. Blood 65:227, 1985
20. Frelinger AL, Cohen I, Plow EF, Smith MA, Roberts J, Lam S C-T, Ginsberg MH: Selective inhibition of integrin function by antibodies specific for ligand-occupied receptor conformers. J Biol Chem 265:6346, 1990
21. Vu T-KH, Hung DT, Wheaton V, Coughlin S: Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64:1057, 1991
22. Wencel-Drake JD: Plasma membrane GP IIb/IIIa: Evidence for a cycling receptor pool. Am J Pathol 136:61, 1990
23. Peerschke EIB, Wainer JA: Examination of irreversible platelet-fibrinogen interactions. Am J Physiol 248:C466, 1985
24. Peerschke EIB: Irreversible platelet-fibrinogen interactions occur independently of fibrinogen α-chain degradation and are not mediated by intact platelet membrane glycoprotein IIb-IIIa complexes. J Lab Clin Med 111:84, 1988
25. Penny WF, Ware JA: Platelet activation and subsequent inhibition by plasmin and recombinant tissue-type plasminogen activator. Blood 79:91, 1992
26. Michelson AD, Barnard MR: Plasmin-induced redistribution of platelet glycoprotein Ib. Blood 76:2005, 1990
27. Cramer EM, Lu H, Caen JP, Soria C, Berndt MC, Tenza D: Differential redistribution of platelet glycoproteins Ib and IIb-IIIa after plasmin stimulation. Blood 77:694, 1991
28. Rabhi-Sabile S, Pidard D: Exposure of human platelets to plasmin results in the expression of irreversibly active fibrinogen receptors. Thromb Haemost 73:693, 1995
29. Hantgan RR: An investigation of fibrin-platelet adhesive interactions by microfluorimetry. Biochim Biophys Acta 927:55, 1987
30. Sklar LA, Finney DA, Oades ZG, Jesaitis AJ, Painter RG, Cochrane CG: The dynamics of ligand-receptor interactions. Real-time analyses of association, dissociation, and internalization of an N-formyl peptide and its receptors on the human neutrophil. J Biol Chem 259:5661, 1984
31. Stormorken H, Gogstad GO, Solum NO, Pande H: Diagnosis of heterozygotes in Glanzmann's thrombasthenia. Thromb Haemost 48:217, 1982
32. George JN, Caen JP, Nurden AT: Glanzmann's thrombasthenia: The spectrum of clinical disease Blood 75:1383, 1990
33. Peerschke EIB: Effect of stimulation on the stabilization of platelet-fibrinogen interactions. Thromb Haemost 68:346, 1992
34. Parise LV, Steiner B, Nannizzi L, Criss AB, Phillips DR: Evidence for novel binding sites on the platelet GPIIb and IIIa subunits and immobilized fibrinogen. Biochem J 289:445, 1993
35. Peerschke EIB: Irreversible fibrinogen binding is an integral property of GPIIb-IIIa. Blood 82:211a, 1993 (abstr, suppl I)
36. 3 and its ligand. J Biol Chem 266:19543, 1991
37. 3 integrin reconstituted into planar lipid bilayer. J Biol Chem 268:6800, 1993
38. Harrison P, Wilbourn B, Debili N, Vainchenker W, Breton-Gorius J, Lawrie AS, Masse JM, Savidge GF, Cramer EM: Uptake of plasma fibrinogen into the α-granules of human megakaryocytes and platelets. J Clin Invest 84:1320, 1989
39. Handagama P, Rappolee DA, Werb Z, Levin J, Bainton DF: Platelet α-granule fibrinogen, albumin and IgG are not synthesized by rat and mouse megakaryocytes. J Clin Invest 86:1364, 1990
40. 3 (glycoprotein IIb-IIIa). Blood 82:135, 1993
41. George JN: Platelet immunoglobulin G· Its significance for the evaluation of thrombocytopenia and for understanding the origin of α-granule proteins. Blood 76:859, 1990
42. Belloc F, Heilman E, Combrie R, Boisseau MR, Nurden AT: Protein synthesis and storage in human platelets: A defective storage of fibrinogen in patients with Glanzmann's thrombasthenia. Biochim Biophys Acta 925:218, 1987
43. Morgenstern E, Ruf A, Patscheke H: Transport of anti-glycoprotein IIb/IIIa-antibodies into the α-granules of unstimulated human blood platelets. Thromb Haemost 67:121, 1992
44. 3 (platelet GPIIb-IIIa) dependent homotypic and heterotypic cell-cell interactions. J Clin Invest 88:1128, 1991
45. 2-adrenergic receptor from calf lung. Biochim Biophys Acta 861:345, 1986
46. Panse LV, Helgerson SL, Steiner B, Nannizzi L, Phillips DR: Synthetic peptides derived from fibrinogen and fibronectin change the conformation of purified platelet glycoprotein IIb-IIIa. J Biol Chem 262:12597, 1987
47. Sczekan MM, Juliano RL: Internalization of the fibronectin receptor is a constitutive process. J Cell Physiol 142:574, 1990
48. 1, or LFA-1. EMBO J 11:405, 1992
49. 5 integrin receptor regulates receptor-mediated endocytosis of vitronectin. J Biol Chem 268:11492, 1993
50. Bretscher MS: Endocytosis and recycling of the fibronectin in CHO cells. EMBO J 8:1341, 1989
51. Raub TJ, Kuentzel SL: Kinetic and morphological evidence for endocytosis of mammalian cell integrin receptors by using an anti-fibronectin receptor β subunit monoclonal antibody. Exp Cell Res 184:407, 1989
52. 1 integrin ligand invasin J Exp Med 177:207, 1993
53. Haverstick DM, Cowan JF, Yamada KM, Santoro SA. Inhibition of platelet activation to fibronectin, fibrinogen and von Wille-brand factor substrates by a synthetic tetrapeptide derived from the cell binding domain of fibronectin. Blood 66:946, 1985
54. 3 on platelet α-granule fibrinogen. Br J Haematol 82:721, 1992
55. Suzuki M, Kawakatsu T, Nagata H, Hamamoto K, Iwata K, Ohga S, Nomura S, Kokaea T, Yasunaga K: Effects of injected antibody against the platelet glycoprotein IIb/IIIa complex on monkey platelet fibrinogen. Thromb Haemost 67:578, 1992
56. George JN: Platelet behavior and aging in the circulation. Prog Clin Biol Res 28:39, 1978
57. Ruggert ZM: Mechanisms of shear-induced platelet adhesion and aggregation. Thromb Haemost 70:119, 1993
58. Ball G, Brereton GG, Fulwood M, Ireland DM, Yates P. Effect of prostaglandin El alone and in combination with theophylline or aspirin on collagen-induced platelet aggregation and on platelet nucleotides including adenosine 3′:5′-cyclic monophosphate. Biochem J 120:709, 1970
59. Radomski MW, Palmer RM, Moncada S: An L-arginine/nitric oxide pathway present in human platelets regulates aggregation. Proc Natl Acad Sci USA 87:5193, 1990