-
1
-
-
0018641190
-
Erythropoietin levels in uremic nephric and anephric patients
-
Caro J., Brown S., Miller O., et al. Erythropoietin levels in uremic nephric and anephric patients. J Lab Clin Med 93 (1979) 449-458
-
(1979)
J Lab Clin Med
, vol.93
, pp. 449-458
-
-
Caro, J.1
Brown, S.2
Miller, O.3
-
2
-
-
0029371783
-
The rate and control of baseline red cell production in hematologically stable patients with uremia
-
Erslev A.J., and Besarab A. The rate and control of baseline red cell production in hematologically stable patients with uremia. J Lab Clin Med 126 (1995) 283-286
-
(1995)
J Lab Clin Med
, vol.126
, pp. 283-286
-
-
Erslev, A.J.1
Besarab, A.2
-
3
-
-
0014148007
-
Erythropoietin excretion in man following androgens
-
Alexanian R., Vaughn W.K., and Ruchelman M.W. Erythropoietin excretion in man following androgens. J Lab Clin Med 70 (1967) 777-785
-
(1967)
J Lab Clin Med
, vol.70
, pp. 777-785
-
-
Alexanian, R.1
Vaughn, W.K.2
Ruchelman, M.W.3
-
4
-
-
0017755573
-
Purification of human erythropoietin
-
Miyake T., Kung C.K., and Goldwasser E. Purification of human erythropoietin. J Biol Chem 252 (1977) 5558-5564
-
(1977)
J Biol Chem
, vol.252
, pp. 5558-5564
-
-
Miyake, T.1
Kung, C.K.2
Goldwasser, E.3
-
5
-
-
0242611254
-
Cloning and expression of the human erythropoietin gene
-
Lin F.K., Suggs S., Lin C.H., et al. Cloning and expression of the human erythropoietin gene. Proc Natl Acad Sci U S A 82 (1985) 7580-7584
-
(1985)
Proc Natl Acad Sci U S A
, vol.82
, pp. 7580-7584
-
-
Lin, F.K.1
Suggs, S.2
Lin, C.H.3
-
6
-
-
0034997401
-
Development and characterization of novel erythropoiesis stimulating protein (NESP)
-
Egrie J.C., and Browne J.K. Development and characterization of novel erythropoiesis stimulating protein (NESP). Br J Cancer 84 suppl 1 (2001) 3-10
-
(2001)
Br J Cancer
, vol.84
, Issue.SUPPL. 1
, pp. 3-10
-
-
Egrie, J.C.1
Browne, J.K.2
-
7
-
-
0032737391
-
Pharmacokinetics of novel erythropoiesis stimulating protein compared with epoetin alfa in dialysis patients
-
Macdougall I.C., Gray S.J., Elston O., et al. Pharmacokinetics of novel erythropoiesis stimulating protein compared with epoetin alfa in dialysis patients. J Am Soc Nephrol 10 (1999) 2392-2395
-
(1999)
J Am Soc Nephrol
, vol.10
, pp. 2392-2395
-
-
Macdougall, I.C.1
Gray, S.J.2
Elston, O.3
-
8
-
-
0036436322
-
Randomized trial of darbepoetin alfa for treatment of renal anemia at a reduced dose frequency compared with rHuEPO in dialysis patients
-
European/Australian NESP 970200 Study Group
-
Vanrenterghem Y., Barany P., Mann J.F., et al., European/Australian NESP 970200 Study Group. Randomized trial of darbepoetin alfa for treatment of renal anemia at a reduced dose frequency compared with rHuEPO in dialysis patients. Kidney Int 62 (2002) 2167-2175
-
(2002)
Kidney Int
, vol.62
, pp. 2167-2175
-
-
Vanrenterghem, Y.1
Barany, P.2
Mann, J.F.3
-
9
-
-
0036280663
-
Randomized, controlled trial of darbepoetin alfa for the treatment of anemia in hemodialysis patients
-
Nissenson A.R., Swan S.K., Lindberg J.S., et al. Randomized, controlled trial of darbepoetin alfa for the treatment of anemia in hemodialysis patients. Am J Kidney Dis 40 (2002) 110-118
-
(2002)
Am J Kidney Dis
, vol.40
, pp. 110-118
-
-
Nissenson, A.R.1
Swan, S.K.2
Lindberg, J.S.3
-
10
-
-
0037075272
-
Pure red-cell aplasia and anti-erythropoietin antibodies in patients treated with recombinant erythropoietin
-
Casadevall N., Nataf J., Viron B., et al. Pure red-cell aplasia and anti-erythropoietin antibodies in patients treated with recombinant erythropoietin. N Engl J Med 346 (2002) 469-475
-
(2002)
N Engl J Med
, vol.346
, pp. 469-475
-
-
Casadevall, N.1
Nataf, J.2
Viron, B.3
-
11
-
-
33750846176
-
Guideline on Comparability of Medicinal Products Containing Biotechnology-Derived Proteins as Active Substance
-
Committee for Proprietary Medicinal Products, Evaluation of Medicines for Human Use, The European Agency for the Evaluation of Medicinal Products, London
-
Committee for Proprietary Medicinal Products. Guideline on Comparability of Medicinal Products Containing Biotechnology-Derived Proteins as Active Substance. Quality Issues (2003), Evaluation of Medicines for Human Use, The European Agency for the Evaluation of Medicinal Products, London
-
(2003)
Quality Issues
-
-
-
12
-
-
19044395847
-
Follow-on biologics: Challenges of the 'next generation.'
-
Schellekens H. Follow-on biologics: Challenges of the 'next generation.'. Nephrol Dial Transplant 20 suppl 4 (2005) iv31-iv36
-
(2005)
Nephrol Dial Transplant
, vol.20
, Issue.SUPPL. 4
-
-
Schellekens, H.1
-
13
-
-
33644875091
-
CERA (continuous erythropoietin receptor activator): A new erythropoiesis-stimulating agent for the treatment of anemia
-
Macdougall I.C. CERA (continuous erythropoietin receptor activator): A new erythropoiesis-stimulating agent for the treatment of anemia. Curr Hematol Rep 4 (2005) 436-440
-
(2005)
Curr Hematol Rep
, vol.4
, pp. 436-440
-
-
Macdougall, I.C.1
-
14
-
-
0042363938
-
The discovery and characterization of CERA, an innovative agent for the treatment of anemia
-
(abstr)
-
Haselbeck A., Bailon P., Pahlke W., et al. The discovery and characterization of CERA, an innovative agent for the treatment of anemia. Blood 100 (2002) 227A (abstr)
-
(2002)
Blood
, vol.100
-
-
Haselbeck, A.1
Bailon, P.2
Pahlke, W.3
-
15
-
-
33748150635
-
CERA (continuous erythropoiesis receptor activator): Dose-response, pharmacokinetics and tolerability in phase I multiple ascending dose studies
-
(abstr, suppl 15).
-
Dougherty F.C., Reigner B., Jordan P., et al. CERA (continuous erythropoiesis receptor activator): Dose-response, pharmacokinetics and tolerability in phase I multiple ascending dose studies. J Clin Oncol 22 (2004) 14S (abstr, suppl 15).
-
(2004)
J Clin Oncol
, vol.22
-
-
Dougherty, F.C.1
Reigner, B.2
Jordan, P.3
-
16
-
-
33750863831
-
Pharmacologic profile of CERA (continuous erythropoietin receptor activator) in chronic kidney disease patients following intravenous and subcutaneous administration
-
Macdougall I.C., Robson R., Opatrna S., et al. Pharmacologic profile of CERA (continuous erythropoietin receptor activator) in chronic kidney disease patients following intravenous and subcutaneous administration. J Am Soc Nephrol 16 (2005) 759A
-
(2005)
J Am Soc Nephrol
, vol.16
-
-
Macdougall, I.C.1
Robson, R.2
Opatrna, S.3
-
17
-
-
1542322136
-
Subcutaneous CERA (continuous erythropoiesis receptor activator) has potent erythropoietic activity in dialysis patients with chronic renal anemia: An exploratory multiple-dose study
-
(abstr).
-
de Francisco A.L., Sulowicz W., and Dougherty F.C. Subcutaneous CERA (continuous erythropoiesis receptor activator) has potent erythropoietic activity in dialysis patients with chronic renal anemia: An exploratory multiple-dose study. J Am Soc Nephrol 14 (2003) 27A-28A (abstr).
-
(2003)
J Am Soc Nephrol
, vol.14
-
-
de Francisco, A.L.1
Sulowicz, W.2
Dougherty, F.C.3
-
18
-
-
22244441694
-
CERA (continuous erythropoietin receptor activator) administered up to once every 3 weeks corrects anemia in patients with chronic kidney disease not on dialysis
-
BA16528 Study Group (abstr)
-
Provenzano R., Besarab A., Macdougall I.C., et al., BA16528 Study Group. CERA (continuous erythropoietin receptor activator) administered up to once every 3 weeks corrects anemia in patients with chronic kidney disease not on dialysis. J Am Soc Nephrol 15 (2004) 544A (abstr)
-
(2004)
J Am Soc Nephrol
, vol.15
-
-
Provenzano, R.1
Besarab, A.2
Macdougall, I.C.3
-
20
-
-
33748332090
-
CERA (continuous erythropoietin receptor activator) maintains hemoglobin levels in dialysis patients when administered subcutaneously up to once every 4 weeks
-
BA16286 Study Group (abstr)
-
Locatelli F., Villa G., Arias M., et al., BA16286 Study Group. CERA (continuous erythropoietin receptor activator) maintains hemoglobin levels in dialysis patients when administered subcutaneously up to once every 4 weeks. J Am Soc Nephrol 15 (2004) 543A (abstr)
-
(2004)
J Am Soc Nephrol
, vol.15
-
-
Locatelli, F.1
Villa, G.2
Arias, M.3
-
21
-
-
33748323764
-
CERA (continuous erythropoietin receptor activator) in patients with multiple myeloma: An exploratory phase I-II dose escalation study
-
Dmoszynska A., Kloczko J., Rokicka M., et al. CERA (continuous erythropoietin receptor activator) in patients with multiple myeloma: An exploratory phase I-II dose escalation study. J Clin Oncol 22 suppl 15 (2004) 14S
-
(2004)
J Clin Oncol
, vol.22
, Issue.SUPPL. 15
-
-
Dmoszynska, A.1
Kloczko, J.2
Rokicka, M.3
-
22
-
-
9444236174
-
Small peptides as potent mimetics of the protein hormone erythropoietin
-
Wrighton N.C., Farrell F.X., Chang R., et al. Small peptides as potent mimetics of the protein hormone erythropoietin. Science 273 (1996) 458-464
-
(1996)
Science
, vol.273
, pp. 458-464
-
-
Wrighton, N.C.1
Farrell, F.X.2
Chang, R.3
-
23
-
-
33747601907
-
Preclinical evaluation of Hematide™, a novel erythropoietic receptor agonist for the treatment of anemia caused by kidney disease
-
(abstr)
-
Woodburn K., Fan Q., Holmes C.P., et al. Preclinical evaluation of Hematide™, a novel erythropoietic receptor agonist for the treatment of anemia caused by kidney disease. Blood 104 (2004) (abstr)
-
(2004)
Blood
, vol.104
-
-
Woodburn, K.1
Fan, Q.2
Holmes, C.P.3
-
24
-
-
33750895632
-
-
™, a peptidic erythropoiesis stimulating agent that corrects anemia induced by partial nephrectomy and erythropoietin-specific antibodies in rats. Abstract presented at European Haematology Association, Stockholm, June, 2005
-
-
-
-
25
-
-
33750873380
-
-
Stead R, Lambert J, Wessels D, et al: Hematide™, a synthetic peptide-based erythropoiesis stimulating agent (ESA), demonstrates dose dependent activity in a phase 1 single dose, dose escalating study in normal healthy volunteers. Abstract presented at European Haematology Association, Stockholm, June, 2005
-
-
-
-
27
-
-
33744832240
-
Upregulation of endogenous EPO in healthy subjects by inhibition of HIF-PH
-
Urquilla P., Fong A., Oksanen S., et al. Upregulation of endogenous EPO in healthy subjects by inhibition of HIF-PH. J Am Soc Nephrol 15 (2004) 546A
-
(2004)
J Am Soc Nephrol
, vol.15
-
-
Urquilla, P.1
Fong, A.2
Oksanen, S.3
-
28
-
-
33745868930
-
Pharmacological stabilization of HIF increases hemoglobin concentration in anemic patients with chronic kidney disease
-
Wiecek A., Piecha G., Ignacy W., et al. Pharmacological stabilization of HIF increases hemoglobin concentration in anemic patients with chronic kidney disease. Nephrol Dial Transplant 20 suppl 5 (2005) v195
-
(2005)
Nephrol Dial Transplant
, vol.20
, Issue.SUPPL. 5
-
-
Wiecek, A.1
Piecha, G.2
Ignacy, W.3
-
29
-
-
0142182781
-
HIF-1: An oxygen response system with special relevance to the kidney
-
Maxwell P. HIF-1: An oxygen response system with special relevance to the kidney. J Am Soc Nephrol 14 (2003) 2712-2722
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 2712-2722
-
-
Maxwell, P.1
-
30
-
-
0037423148
-
Design and chemical synthesis of a homogeneous polymer-modified erythropoiesis protein
-
Kochendoerfer G.G., Chen S.Y., Mao F., et al. Design and chemical synthesis of a homogeneous polymer-modified erythropoiesis protein. Science 299 (2003) 884-887
-
(2003)
Science
, vol.299
, pp. 884-887
-
-
Kochendoerfer, G.G.1
Chen, S.Y.2
Mao, F.3
-
31
-
-
0033609857
-
An erythropoietin fusion protein comprised of identical repeating domains exhibits enhanced biological properties
-
Sytkowski A.J., Lunn E.D., Risinger M.A., et al. An erythropoietin fusion protein comprised of identical repeating domains exhibits enhanced biological properties. J Biol Chem 274 (1999) 24773-24778
-
(1999)
J Biol Chem
, vol.274
, pp. 24773-24778
-
-
Sytkowski, A.J.1
Lunn, E.D.2
Risinger, M.A.3
-
33
-
-
0028956353
-
Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals
-
Klingmuller U., Lorenz U., Cantley L.C., et al. Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell 80 (1995) 729-738
-
(1995)
Cell
, vol.80
, pp. 729-738
-
-
Klingmuller, U.1
Lorenz, U.2
Cantley, L.C.3
-
34
-
-
13544262341
-
Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer
-
Rivera V.M., Gao G.P., Grant R.L., et al. Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer. Blood 105 (2005) 1424-1430
-
(2005)
Blood
, vol.105
, pp. 1424-1430
-
-
Rivera, V.M.1
Gao, G.P.2
Grant, R.L.3
-
35
-
-
3142663065
-
Survival of encapsulated human primary fibroblasts and erythropoietin expression under xenogeneic conditions
-
Schwenter F., Schneider B.L., Pralong W.F., et al. Survival of encapsulated human primary fibroblasts and erythropoietin expression under xenogeneic conditions. Hum Gene Ther 15 (2004) 669-680
-
(2004)
Hum Gene Ther
, vol.15
, pp. 669-680
-
-
Schwenter, F.1
Schneider, B.L.2
Pralong, W.F.3
-
36
-
-
0036785428
-
Long-term reversal of chronic anemia using a hypoxia-regulated erythropoietin gene therapy
-
Binley K., Askham Z., Iqball S., et al. Long-term reversal of chronic anemia using a hypoxia-regulated erythropoietin gene therapy. Blood 100 (2002) 2406-2413
-
(2002)
Blood
, vol.100
, pp. 2406-2413
-
-
Binley, K.1
Askham, Z.2
Iqball, S.3
|