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Volumn 177, Issue 10, 2006, Pages 7050-7058

The immunosuppressant cyclosporin A antagonizes human formyl peptide receptor through inhibition of cognate ligand binding

Author keywords

[No Author keywords available]

Indexed keywords

ASCOMYCIN; BETA GLUCURONIDASE; BUCLADESINE; CALCIUM ION; CYCLOSPORIN A; CYCLOSPORIN DERIVATIVE; CYCLOSPORIN H; FORMYLPEPTIDE RECEPTOR; IODINE 125; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; TRITIUM;

EID: 33750841010     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.177.10.7050     Document Type: Article
Times cited : (34)

References (40)
  • 1
    • 0001596987 scopus 로고
    • Role of chemotaxis in inflammation
    • Harris, H. 1954. Role of chemotaxis in inflammation. Physiol. Rev. 34: 529 -562.
    • (1954) Physiol. Rev. , vol.34 , pp. 529-562
    • Harris, H.1
  • 2
    • 0002803815 scopus 로고
    • Phagocytic cells: Stimulus-response coupling mechanisms
    • J. I. Gallin, I. M. Goldstein, and R. Snyderman, eds. Raven Press, New York
    • Snyderman, R., and R. J. Uhing. 1992. Phagocytic cells: stimulus-response coupling mechanisms. In Inflammation: Basic Principles and Clinical Correlates. J. I. Gallin, I. M. Goldstein, and R. Snyderman, eds. Raven Press, New York, pp. 421-439.
    • (1992) Inflammation: Basic Principles and Clinical Correlates , pp. 421-439
    • Snyderman, R.1    Uhing, R.J.2
  • 3
    • 0025615835 scopus 로고
    • The human n-formylpeptide receptor: Characterization of two cDNA isolates and evidence for a new subfamily of G-protein-coupled receptors
    • Boulay, F., M. Tardif, L. Brouchon, and P. Vignais. 1990. The human n-formylpeptide receptor: characterization of two cDNA isolates and evidence for a new subfamily of G-protein-coupled receptors. Biochemistry 29: 11123-11133.
    • (1990) Biochemistry , vol.29 , pp. 11123-11133
    • Boulay, F.1    Tardif, M.2    Brouchon, L.3    Vignais, P.4
  • 4
    • 0028202481 scopus 로고
    • The molecular biology of leukocyte chemoattractant receptors
    • Murphy, P. M. 1994. The molecular biology of leukocyte chemoattractant receptors. Annu. Rev. Immunol. 12: 593-633.
    • (1994) Annu. Rev. Immunol. , vol.12 , pp. 593-633
    • Murphy, P.M.1
  • 5
    • 0030748297 scopus 로고    scopus 로고
    • The N-formylpeptide receptor: A model for the study of chemoattractant receptor structure and function
    • Prossnitz, E. R., and R. D. Ye. 1997. The N-formylpeptide receptor: a model for the study of chemoattractant receptor structure and function. Pharmacol. Ther. 74: 73-102.
    • (1997) Pharmacol. Ther. , vol.74 , pp. 73-102
    • Prossnitz, E.R.1    Ye, R.D.2
  • 6
    • 0036839229 scopus 로고    scopus 로고
    • Formyl-peptide receptors revisited
    • Le, Y., P. M. Murphy, and J. M. Wang. 2002. Formyl-peptide receptors revisited. Trends Immunol. 23: 541-548.
    • (2002) Trends Immunol. , vol.23 , pp. 541-548
    • Le, Y.1    Murphy, P.M.2    Wang, J.M.3
  • 7
    • 0033557172 scopus 로고    scopus 로고
    • Impaired anti-bacterial host defense in mice lacking the N-formyl peptide receptor
    • Gao, J.-L., E. J. Lee, and P. M. Murphy. 1999. Impaired anti-bacterial host defense in mice lacking the N-formyl peptide receptor. J. Exp. Med. 189: 657-662.
    • (1999) J. Exp. Med. , vol.189 , pp. 657-662
    • Gao, J.-L.1    Lee, E.J.2    Murphy, P.M.3
  • 8
    • 0024953527 scopus 로고
    • Pharmacology of cyclosporine (sandimmune). V. Pharmacological effects on immune function: In vitro studies
    • Di Padova, F. E. 1990. Pharmacology of cyclosporine (sandimmune). V. Pharmacological effects on immune function: in vitro studies. Pharmacol. Rev. 41: 373-405.
    • (1990) Pharmacol. Rev. , vol.41 , pp. 373-405
    • Di Padova, F.E.1
  • 9
    • 0022872049 scopus 로고
    • Mechanism of action of cyclosporine: Role of calmodulin, cyclophilin, and other cyclosporine-binding proteins
    • Hess, A. D., and P. M. Colombani. 1986. Mechanism of action of cyclosporine: role of calmodulin, cyclophilin, and other cyclosporine-binding proteins. Transplant. Proc. 18: 219-237.
    • (1986) Transplant. Proc. , vol.18 , pp. 219-237
    • Hess, A.D.1    Colombani, P.M.2
  • 10
    • 0022556579 scopus 로고
    • Chemistry of the natural cyclosporin metabolites
    • von Wartburg, A., and R. Traber. 1986. Chemistry of the natural cyclosporin metabolites. Prog. Allergy 38: 28-45.
    • (1986) Prog. Allergy , vol.38 , pp. 28-45
    • Von Wartburg, A.1    Traber, R.2
  • 11
    • 0026072894 scopus 로고
    • Differential inhibition of human neutrophil activation by cyclosporins A, D, and H. Cyclosporin H is a potent and effective inhibitor of formyl peptide-induced superoxide formation
    • Wenzel-Seifert, K., L. Grunbaum, and R. Seifert. 1991. Differential inhibition of human neutrophil activation by cyclosporins A, D, and H. Cyclosporin H is a potent and effective inhibitor of formyl peptide-induced superoxide formation. J. Immunol. 147: 1940-1946.
    • (1991) J. Immunol. , vol.147 , pp. 1940-1946
    • Wenzel-Seifert, K.1    Grunbaum, L.2    Seifert, R.3
  • 12
    • 0027154675 scopus 로고
    • Cyclosporin H is a potent and selective formyl peptide receptor antagonist. Comparison with N-t-butoxycarbonyl-L-phenylalanyl-L-leucyl-L- phenylalanyl-L-leucyl-L-phenylalanine and cyclosporins A, B, C, D, and e
    • Wenzel-Seifert, K., and R. Seifert. 1993. Cyclosporin H is a potent and selective formyl peptide receptor antagonist. Comparison with N-t-butoxycarbonyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-leucyl-L- phenylalanine and cyclosporins A, B, C, D, and E. J. Immunol. 150: 4591-4599.
    • (1993) J. Immunol. , vol.150 , pp. 4591-4599
    • Wenzel-Seifert, K.1    Seifert, R.2
  • 13
    • 0032508632 scopus 로고    scopus 로고
    • High constitutive activity of the human formyl peptide receptor
    • Wenzel-Seifert, K., C. M. Hurt, and R. Seifert. 1998. High constitutive activity of the human formyl peptide receptor. J. Biol. Chem. 273: 24181-24189.
    • (1998) J. Biol. Chem. , vol.273 , pp. 24181-24189
    • Wenzel-Seifert, K.1    Hurt, C.M.2    Seifert, R.3
  • 14
    • 0037057560 scopus 로고    scopus 로고
    • Cyclosporins: Structure-activity relationships for the inhibition of the human FPR1 formylpeptide receptor
    • Loor, F., F. Tiberghien, T. Wenandy, A. Didier, and R. Traber. 2002. Cyclosporins: structure-activity relationships for the inhibition of the human FPR1 formylpeptide receptor. J. Med. Chem. 45: 4613-4628.
    • (2002) J. Med. Chem. , vol.45 , pp. 4613-4628
    • Loor, F.1    Tiberghien, F.2    Wenandy, T.3    Didier, A.4    Traber, R.5
  • 15
    • 0025787142 scopus 로고
    • Immunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription
    • Hultsch, T., M. W. Albers, S. L. Schreiber, and R. J. Hohman. 1991. Immunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription. Proc. Natl. Acad. Sci. USA 88: 6229-6233.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 6229-6233
    • Hultsch, T.1    Albers, M.W.2    Schreiber, S.L.3    Hohman, R.J.4
  • 16
    • 0026503793 scopus 로고
    • Identity of immunosuppressant FR-900520 with ascomycin
    • Morisaki, M., and T. Arai. 1992. Identity of immunosuppressant FR-900520 with ascomycin. J. Antibiot. 45: 126-128.
    • (1992) J. Antibiot. , vol.45 , pp. 126-128
    • Morisaki, M.1    Arai, T.2
  • 17
    • 0021282527 scopus 로고
    • Studies on cyclosporins produced by Fusarium solani sp. No. 4-11: Isolation, separation, purification and identification
    • Hong, L., X. Tang, C. Miao, and Y. Wang. 1984. Studies on cyclosporins produced by Fusarium solani sp. No. 4-11: isolation, separation, purification and identification. Kangshengsu 9: 5-15.
    • (1984) Kangshengsu , vol.9 , pp. 5-15
    • Hong, L.1    Tang, X.2    Miao, C.3    Wang, Y.4
  • 18
    • 0035685546 scopus 로고    scopus 로고
    • Cyclosporin H produced by Fusarium solani: Purification and structure identification
    • Zheng, W., J. Zhou, Q. Wen, and J. Zhang. 2001. Cyclosporin H produced by Fusarium solani: purification and structure identification. Chin. J. Antibiot. 26: 417-419.
    • (2001) Chin. J. Antibiot. , vol.26 , pp. 417-419
    • Zheng, W.1    Zhou, J.2    Wen, Q.3    Zhang, J.4
  • 19
    • 0034667987 scopus 로고    scopus 로고
    • The synthetic peptide Trp-Lys-Tyr-Met-Val-D-Met is a potent chemotactic agonist for mouse formyl peptide receptor
    • He, R., L. Tan, D. D. Browning, J. M. Wang, and R. D. Ye. 2000. The synthetic peptide Trp-Lys-Tyr-Met-Val-D-Met is a potent chemotactic agonist for mouse formyl peptide receptor. J. Immunol. 165: 4598-4605.
    • (2000) J. Immunol. , vol.165 , pp. 4598-4605
    • He, R.1    Tan, L.2    Browning, D.D.3    Wang, J.M.4    Ye, R.D.5
  • 20
    • 0021361891 scopus 로고
    • Isolation and reconstitution of the N-formylpeptide receptor from HL-60 derived neutrophils
    • Hoyle, P. C., and R. J. Freer. 1984. Isolation and reconstitution of the N-formylpeptide receptor from HL-60 derived neutrophils. FEBS 167: 277-280.
    • (1984) FEBS , vol.167 , pp. 277-280
    • Hoyle, P.C.1    Freer, R.J.2
  • 21
    • 0018717551 scopus 로고
    • Discontinuous density gradient separation of human mononuclear leucocytes using Percoll as gradient medium
    • Ulmer, A. J., and H. D. Flad. 1979. Discontinuous density gradient separation of human mononuclear leucocytes using Percoll as gradient medium. J. Immunol. Methods 30: 1-10.
    • (1979) J. Immunol. Methods , vol.30 , pp. 1-10
    • Ulmer, A.J.1    Flad, H.D.2
  • 23
    • 0033601289 scopus 로고    scopus 로고
    • Chemoattractant receptors activate distinct pathways for chemotaxis and secretion. Role of G-protein usage
    • Haribabu, B., D. V. Zhelev, B. C. Pridgen, R. M. Richardson, H. Ali, and R. Snyderman. 1999. Chemoattractant receptors activate distinct pathways for chemotaxis and secretion. Role of G-protein usage. J. Biol. Chem. 274: 37087-37092.
    • (1999) J. Biol. Chem. , vol.274 , pp. 37087-37092
    • Haribabu, B.1    Zhelev, D.V.2    Pridgen, B.C.3    Richardson, R.M.4    Ali, H.5    Snyderman, R.6
  • 25
    • 0030997435 scopus 로고    scopus 로고
    • Granules of the human neutrophilic polymorphonuclear leukocyte
    • Borregaard, N., and J. B. Cowland. 1997. Granules of the human neutrophilic polymorphonuclear leukocyte. Blood 89: 3503-3521.
    • (1997) Blood , vol.89 , pp. 3503-3521
    • Borregaard, N.1    Cowland, J.B.2
  • 26
    • 0018828937 scopus 로고
    • A subpopulation of cultured human promyelocytic leukemia cells (HL-60) displays the formyl peptide chemotactic receptor
    • Niedel, J., I. Kahane, L. Lachman, and P. Cuatrecasas. 1980. A subpopulation of cultured human promyelocytic leukemia cells (HL-60) displays the formyl peptide chemotactic receptor. Proc. Natl. Acad. Sci. USA 77: 1000-1004.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 1000-1004
    • Niedel, J.1    Kahane, I.2    Lachman, L.3    Cuatrecasas, P.4
  • 27
    • 0031695577 scopus 로고    scopus 로고
    • Ascomycin macrolactam derivative SDZ ASM 981 inhibits the release of granule-associated mediators and of newly synthesized cytokines in RBL 2H3 mast cells in an immunophilin-dependent manner
    • Hultsch, T., K. D. Muller, J. G. Meingassner, M. Grassberger, R. E. Schopf, and J. Knop. 1998. Ascomycin macrolactam derivative SDZ ASM 981 inhibits the release of granule-associated mediators and of newly synthesized cytokines in RBL 2H3 mast cells in an immunophilin-dependent manner. Arch. Dermatol. Res. 290: 501-507.
    • (1998) Arch. Dermatol. Res. , vol.290 , pp. 501-507
    • Hultsch, T.1    Muller, K.D.2    Meingassner, J.G.3    Grassberger, M.4    Schopf, R.E.5    Knop, J.6
  • 29
    • 0037057583 scopus 로고    scopus 로고
    • Cyclosporins: Structure-activity relationships for the inhibition of the human MDR1 P-glycoprotein ABC transporter
    • Loor, F., F. Tiberghien, T. Wenandy, A. Didier, and R. Traber. 2002. Cyclosporins: structure-activity relationships for the inhibition of the human MDR1 P-glycoprotein ABC transporter. J. Med. Chem. 45: 4598-4612.
    • (2002) J. Med. Chem. , vol.45 , pp. 4598-4612
    • Loor, F.1    Tiberghien, F.2    Wenandy, T.3    Didier, A.4    Traber, R.5
  • 31
    • 0027234360 scopus 로고
    • Partial inhibition of human neutrophil activation by FK-506 at supratherapeutic concentrations
    • Wenzel-Seifert, K., and R. Seifert. 1993. Partial inhibition of human neutrophil activation by FK-506 at supratherapeutic concentrations. Naunyn-Schmiedeberg's Arch. Pharmacol. 348: 7-13.
    • (1993) Naunyn-Schmiedeberg's Arch. Pharmacol. , vol.348 , pp. 7-13
    • Wenzel-Seifert, K.1    Seifert, R.2
  • 32
    • 0029776477 scopus 로고    scopus 로고
    • Cyclosporin H is a potent and selective competitive antagonist of human basophil activation by N-formyl-methionyl-leucyl-phenylalanine
    • de Paulis, A., A. Ciccarelli, G. de Crescenzo, R. Cirillo, V. Patella, and G. Marone. 1996. Cyclosporin H is a potent and selective competitive antagonist of human basophil activation by N-formyl-methionyl-leucyl- phenylalanine. J. Allergy Clin. Immunol. 98: 152-164.
    • (1996) J. Allergy Clin. Immunol. , vol.98 , pp. 152-164
    • De Paulis, A.1    Ciccarelli, A.2    De Crescenzo, G.3    Cirillo, R.4    Patella, V.5    Marone, G.6
  • 34
    • 0032562690 scopus 로고    scopus 로고
    • Identification of a ligand binding site in the human neutrophil formyl peptide receptor using a site-specific fluorescent photoaffinity label and mass spectrometry
    • Mills, J. S., H. M. Miettinen, D. Barnidge, M. J. Vlases, S. Wimer-Mackin, E. A. Dratz, J. Sunner, and A. J. Jesaitis. 1998. Identification of a ligand binding site in the human neutrophil formyl peptide receptor using a site-specific fluorescent photoaffinity label and mass spectrometry. J. Biol. Chem. 273: 10428-10435.
    • (1998) J. Biol. Chem. , vol.273 , pp. 10428-10435
    • Mills, J.S.1    Miettinen, H.M.2    Barnidge, D.3    Vlases, M.J.4    Wimer-Mackin, S.5    Dratz, E.A.6    Sunner, J.7    Jesaitis, A.J.8
  • 36
    • 0025021022 scopus 로고
    • Fluorescence analysis of the size of a binding pocket of a peptide receptor at natural abundance
    • Sklar, L. A., S. P. Fay, B. E. Seligmann, R. J. Freer, N. Muthukumaraswamy, and H. Mueller. 1990. Fluorescence analysis of the size of a binding pocket of a peptide receptor at natural abundance. Biochemistry 29: 313-316.
    • (1990) Biochemistry , vol.29 , pp. 313-316
    • Sklar, L.A.1    Fay, S.P.2    Seligmann, B.E.3    Freer, R.J.4    Muthukumaraswamy, N.5    Mueller, H.6
  • 37
    • 0032742013 scopus 로고    scopus 로고
    • Utilization of two seven-transmembrane, G-protein coupled receptors FPRL1 and FPR by the synthetic hexapeptide WKYMVm for human phagocyte activation
    • Le, Y., W. Gong, B. Li, N. M. Dunlop, W. Shen, S. B. Su, R. D. Ye, P. M. Murphy, and J. M. Wang. 1999. Utilization of two seven-transmembrane, G-protein coupled receptors FPRL1 and FPR by the synthetic hexapeptide WKYMVm for human phagocyte activation. J. Immunol. 163: 6777-6784.
    • (1999) J. Immunol. , vol.163 , pp. 6777-6784
    • Le, Y.1    Gong, W.2    Li, B.3    Dunlop, N.M.4    Shen, W.5    Su, S.B.6    Ye, R.D.7    Murphy, P.M.8    Wang, J.M.9
  • 38
    • 19044398874 scopus 로고    scopus 로고
    • Two-hour postdose concentration: A reliable marker for cyclosporine exposure in adolescents with stable renal transplants
    • John, U., S. Ullrich, M. Roskos, and J. Misselwitz. 2005. Two-hour postdose concentration: a reliable marker for cyclosporine exposure in adolescents with stable renal transplants. Transplant. Proc. 37: 1608-1611.
    • (2005) Transplant. Proc. , vol.37 , pp. 1608-1611
    • John, U.1    Ullrich, S.2    Roskos, M.3    Misselwitz, J.4
  • 40


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