A methodology for the graphical determination of operating conditions of chromatographic sequences incorporating the trade-offs between purity and yield

Journal of Chemical Technology and Biotechnology

Volumn 81, Issue 11, 2006, Pages 1803-1813

  Salisbury, Rebecca S ^a   Bracewell, Daniel G ^a   Titchener Hooker, Nigel J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Chromatography; Sequence modelling; Windows of operation

Indexed keywords

CHEMICAL OPERATIONS; COMPUTER SIMULATION; GRAPHIC METHODS; HYDROPHOBICITY; ION EXCHANGE; MATHEMATICAL MODELS;

HYDROPHOBIC INTERACTION; OPERATING CONDITIONS; SEQUENCE MODELLING;

CHROMATOGRAPHY;

PROTEIN;

CHEMICAL OPERATIONS; CHROMATOGRAPHY; COMPUTER SIMULATION; GRAPHIC METHODS; HYDROPHOBICITY; ION EXCHANGE; MATHEMATICAL MODELS;

ARTICLE; CHEMICAL INTERACTION; CHEMICAL PARAMETERS; CHEMICAL PROCEDURES; CHROMATOGRAPHY; CONTROLLED STUDY; DATA ANALYSIS SOFTWARE; DECISION MAKING; DRUG PURITY; DRUG SYNTHESIS; HYDROPHOBICITY; ION EXCHANGE; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; METHODOLOGY; PROCESS DESIGN; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; PURIFICATION; SEPARATION TECHNIQUE; SIMULATION; SYNTHESIS;

EID: 33750744782     PISSN: 02682575     EISSN: 10974660     Source Type: Journal    
DOI: 10.1002/jctb.1607     Document Type: Article

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