Solid organ transplantation is a reality for patients with HIV infection

Current HIV/AIDS Reports

Volumn 3, Issue 3, 2006, Pages 132-138

  Roland, Michelle E ^a   Stock, Peter G ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADEFOVIR; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; ANTIRETROVIRUS AGENT; ATAZANAVIR; CALCINEURIN INHIBITOR; CYCLOSPORIN; EFAVIRENZ; EMTRICITABINE; ENTECAVIR; HEPATITIS A VACCINE; HEPATITIS B VACCINE; IMMUNOSUPPRESSIVE AGENT; LAMIVUDINE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PNEUMOCOCCUS VACCINE; PROTEINASE INHIBITOR; PROTON PUMP INHIBITOR; RAPAMYCIN; STAVUDINE; TENOFOVIR; TSUKUBAENOLIDE; ZIDOVUDINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

ARTICLE; BONE MARROW TOXICITY; CD4+ T LYMPHOCYTE; DRUG POTENTIATION; DRUG WITHDRAWAL; GRAFT REJECTION; HEALTH CARE PERSONNEL; HEALTH CARE POLICY; HEPATITIS B; HOSPITALIZATION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; KIDNEY ALLOGRAFT REJECTION; KIDNEY TRANSPLANTATION; LIVER GRAFT; NEPHROTOXICITY; ORGAN TRANSPLANTATION; PRACTICE GUIDELINE; REVIEW; TREATMENT OUTCOME;

ANTI-HIV AGENTS; GRAFT REJECTION; HIV INFECTIONS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; ORGAN TRANSPLANTATION; TREATMENT OUTCOME;

EID: 33750724747     PISSN: 15483568     EISSN: 15483576     Source Type: Journal    
DOI: 10.1007/BF02696657     Document Type: Article

References (50)

1. Puoti M, Bruno R, Soriano V, et al.: Hepatocellular carcinoma in HIV-infected patients: epidemiological features, clinical presentation and outcome. AIDS 2004, 18:2285-2293.
2. Rosenthal E, Poiree M, Pradier C, et al.: Mortality due to hepatitis C-related liver disease in HIV-infected patients in France (Mortavic 2001 study). AIDS 2003, 17:1803-1809.
3. Mocroft A, Soriano V, Rockstroh J, et al.: Is there evidence for an increase in the death rate from liver-related disease in patients with HIV? AIDS 2005, 19:2117-2125.
4. Ragni MV, Eghtesad B, Schlesinger KW, et al.: Pretransplant survival is shorter in HIV-positive than HIV-negative subjects with end-stage liver disease. Liver Transpl 2005, 11:1425-1430.
5. Thio CL, Seaberg EC, Skolasky R Jr, et al.: HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS). Lancet 2002, 360:1921-1926.
6. Stock PG: Rapid deterioration of HIV co-infected patients waiting for liver transplantation is not predicted by MELD. Liver Transpl 2005, 11:1315-1317.
7. Palella FJ Jr, Delaney KM, Moorman AC, et al.: Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators. N Engl J Med 1998, 338:853-860.
8. Halpern SD, Ubel PA, Caplan AL: Solid-organ transplantation in HIV-infected patients. N Engl J Med 2002, 347:284-287.
9. Roland ME, Havlir DV: Responding to organ failure in HIV-infected patients. N Engl J Med 2003, 348:2279-2281.
10. Roland ME, Lo B, Braff J, Stock PG: Key clinical, ethical, and policy ssues in the evaluation of the safety and effectiveness of solid organ transplantation in HIV-infected patients. Arch Intern Med 2003, 163:1773-1778.
11. Miro JM, Torre-Cisnero J, Moreno A, et al.: GESIDA/GESITRA-SEIMC, SPNS and ONT consensus document on solid organ transplant (SOT) in HIV-infected patient in Spain 2005. Enferm Infecc Microbiol Clin 2005, 23:353-362.
12. O'Grady J, Taylor C, Brook G: Guidelines for liver transplantation in patients with HIV infection (2005). HIV Med 2005, 6(Suppl 2):149-153.
13. Tien PC: Management and treatment of hepatitis C virus infection in HIV-infected adults: recommendations from the Veterans Affairs Hepatitis C Resource Center Program and National Hepatitis C Program Office. Am J Gastroenterol 2005, 100:2338-2354.
14. Stock PG, Roland ME, Carlson L, et al.: Kidney and liver transplantation in human immunodeficiency virus-infected patients: a pilot safety and efficacy study. Transplantation 2003, 76:370-375.
15. Roland ME, Adey D, Carlson LL, Terrault NA: Kidney and liver transplantation in HIV-infected patients: case presentations and review. AIDS Patient Care STDS 2003, 17:501-507.
16. • Roland ME, Stock PG: Review of solid-organ transplantation in HIV-infected patients. Transplantation 2003, 75:425-429. Contains combined retrospective and prospective multisite data on 45 liver and kidney transplant recipients with HIV infection, suggesting similar patient and graft survival outcomes as the general transplant population.
17. • Ragni MV, Belle SH, Im K, et al.: Survival of human immunodeficiency virus-infected liver transplant recipients. J Infect Dis 2003, 188:1412-1420. Multicenter analysis of liver transplant recipients with HIV infection again suggests that survival is similar in this group compared with the general transplant population. Hepatitis C is associated with poorer survival, and there is a trend towards worse survival in the HIV-HCV co-infected group compared with HCV monoinfected patients.
18. • Abbott KC, Swanson SJ, Agodoa LY, Kimmel PL: Human immunodeficiency virus infection and kidney transplantation in the era of highly active antiretroviral therapy and modern immunosuppression. J Am Soc Nephrol 2004, 15:1633-1639. Retrospective analysis of 47 kidney transplant recipients with HIV infection in a large database, demonstrating excellent patient and graft survival.
19. • Kumar MS, Sierka DR, Damask AM, et al.: Safety and success of kidney transplantation and concomitant immunosuppression in HIV-positive patients. Kidney Int 2005, 67:1622-1629. Prospective study of 40 kidney transplant recipients at Drexel University. Outcomes are good but not as good as in the study by Abbott et al. [18•].
20. Vogel M, Voigt E, Schafer N, et al.: Orthotopic liver transplantation in human immunodeficiency virus (HIV)-positive patients: outcome of 7 patients from the Bonn cohort. Liver Transpl 2005, 11:1515-1521.
21. • Carter JT, Melcher ML, Carlson LL, et al.: Thymoglobulin- associated Cd4+ T-cell depletion and infection risk in HIV-infected renal transplant recipients. Am J Transplant 2006, 6:753-760. Allograft rejection is more common in transplant recipients with HIV infection than in the general transplant population. Kidney transplant recipients who received thymoglobulin were at increased risk for serious non-AIDS-defining infections that required hospitalization.
22. • Frassetto L, Baluom M, Jacobsen W, et al.: Cyclosporine pharmacokinetics and dosing modifications in human immunodeficiency virus-infected liver and kidney transplant recipients. Transplantation 2005, 80:13-17. Cyclosporine doses must be reduced significantly when used with protease-inhibitor-containing antiretroviral regimens.
23. Toso C, Berney T, Oberholzer J, et al.: Kidney-pancreas transplantation in a long-term non-progressor HIV-infected recipient. Am J Transplant 2003, 3:631-633.
24. Tan HP, Kaczorowski DJ, Basu A, et al.: Living-related donor renal transplantation in HIV+ recipients using alemtuzumab preconditioning and steroid-free tacrolimus monotherapy: a single center preliminary experience. Transplantation 2004, 78:1683-1688.
25. Norris S, Taylor C, Muiesan P, et al.: Outcomes of liver transplantation in HIV-infected individuals: the impact of HCV and HBV infection. Liver Transpl 2004, 10:1271-1278.
26. Moreno S, Fortun J, Quereda C, et al.: Liver transplantation in HIV-infected recipients. Liver Transpl 2005, 11:76-81.
27. Rafecas A, Rufi G, Figueras J, et al.: Liver transplantation without steroid induction in HIV-infected patients. Liver Transpl 2004, 10:1320-1323.
28. Radecke K, Fruhauf NR, Miller M, et al.: Outcome after orthotopic liver transplantation in five HIV-infected patients with virus hepatitis-induced cirrhosis. Liver Int 2005, 25:101-108.
29. Honkoop P, Kazemier G, Perenboom RM, et al.: [Liver transplantation in a HIV-positive patient receiving potent antiretroviral therapy; the first case in The Netherlands]. Ned Tijdschr Geneeskd 2004, 148:2500-2504.
30. Terrault NA CJ, Carlson L, Roland M, Stock P. Outcome of patients with hepatitis B virus and human immunodeficiency virus infections referred for liver transplantation. Liver Transpl, In press.
31. Dave MB, Shabih K, Blum S: Maintenance hemodialysis in patients with HIV-associated nephropathy. Clin Nephrol 1998, 50:367-374.
32. Perinbasekar S, Brod-Miller C, Pal S, Mattana J: Predictors of survival in HIV-infected patients on hemodialysis. Am J Nephrol 1996, 16:280-286.
33. Schoenfeld P, Mendelson M, Rodriguez R: Survival of ESRD patients with HIV infection. J Am Soc Nephrol 1995, 6:561.
34. Jain A, Venkataramanan R, Shapiro R, et al.: The interaction between anti-retroviral agents and tacrolimus in liver and kidney transplant patients. Paper presented at the American Transplant Congress. Washington, DC; April 26-May 1, 2002.
35. Guaraldi G, Cocchi S, Codeluppi M, et al.: Role of therapeutic drug monitoring in a patient with human immunodeficiency virus infection and end-stage liver disease undergoing orthotopic liver transplantation. Transplant Proc 2005, 37:2609-2610.
36. Vogel M, Voigt E, Michaelis HC, et al.: Management of drug-to-drug interactions between cyclosporine A and the protease-inhibitor lopinavir/ritonavir in liver-transplanted HIV-infected patients. Liver Transpl 2004, 10:939-944.
37. Chapuis AG, Paolo Rizzardi G, D'Agostino C, et al.: Effects of mycophenolic acid on human immunodeficiency virus infection in vitro and in vivo. Nat Med 2000, 6:762-768.
38. Margolis DM, Kewn S, Coull JJ, et al.: The addition of mycophenolate mofetil to antiretroviral therapy including abacavir is associated with depletion of intracellular deoxyguanosine triphosphate and a decrease in plasma HIV-1 RNA. J Acquir Immune Defic Syndr 2002, 31:45-49.
39. Hossain MM, Coull JJ, Drusano GL, Margolis DM: Dose proportional inhibition of HIV-1 replication by mycophenolic acid and synergistic inhibition in combination with abacavir, didanosine, and tenofovir. Antiviral Res 2002, 55:41-52.
40. Dummer JS, Erb S, Breinig MK, et al.: Infection with human immunodeficiency virus in the Pittsburgh transplant population. A study of 583 donors and 1043 recipients, 1981-1986. Transplantation 1989, 47:134-140.
41. Poli F, Scalamogna M, Pizzi C, et al.: HIV infection in cadaveric renal allograft recipients in the North Italy Transplant Program. Transplantation 1989, 47:724-725.
42. Tzakis AG, Cooper MH, Dummer JS, et al.: Transplantation in HIV+ patients. Transplantation 1990, 49:354-358.
43. Erice A, Rhame FS, Heussner RC, et al.: Human immunodeficiency virus infection in patients with solid-organ transplants: report of five cases and review. Rev Infect Dis 1991, 13:537-547.
44. Bouscarat F, Samuel D, Simon F, et al.: An observational study of 11 French liver transplant recipients infected with human immunodeficiency virus type 1. Clin Infect Dis 1994, 19:854-859.
45. Ahuja TS, Zingman B, Glicklich D: Long-term survival in an HIV-infected renal transplant recipient. Am J Nephrol 1997, 17:480-482.
46. Ragni MV, Bontempo FA, Lewis JH: Organ transplantation in HIV-positive patients with hemophilia [letter]. N Engl J Med 1990, 322:1886-1887.
47. Calabrese LH, Albrecht M, Young J, et al.: Successful cardiac transplantation in an HIV-1-infected patient with advanced disease. N Engl J Med 2003, 348:2323-2328.
48. Vogel M, Voigt E, Wasmuth JC, Brackmann et al.: Orthotopic liver transplantation in HIV-positive patients: outcome of 10 patients from the Bonn cohort. Paper presented at the 12th Conference on Retroviruses and Opportunistic Infections. Boston, MA; February 22-25, 2005.
49. 1999 USPHS/IDSA guidelines for the prevention of opportunistic infections in persons infected with human immunodeficiency virus. U.S. Public Health Service (USPHS) and Infectious Diseases Society of America (IDSA). MMWR Recomm Rep 1999, 48:1-59, 61-66.
50. Palefsky JH, Holly EA. Efirdc JT, et al.: Anal intraepithelial neoplasia in the highly active antiretroviral therapy era among HIV-positive men who have sex with men. AIDS 2005, 19:1407-1414.