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Volumn 26, Issue 5 B, 2006, Pages 3761-3765

Gefitinib efficacy associated with multiple expression of HER family in non-small cell lung cancer

Author keywords

EGFR mutation; Gefitinib; HER2; Molecular target agent; NSCLC; Tyrosine kinase inhibitor

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; GEFITINIB;

EID: 33750723108     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (8)

References (25)
  • 1
    • 0037109014 scopus 로고    scopus 로고
    • ZD1839 (Iressa): An orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy
    • Wakeling AE, Guy SP, Woodburn JR et al: ZD1839 (Iressa): an orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy. Cancer Res 62: 5749-5754, 2002.
    • (2002) Cancer Res , vol.62 , pp. 5749-5754
    • Wakeling, A.E.1    Guy, S.P.2    Woodburn, J.R.3
  • 2
    • 0036569870 scopus 로고    scopus 로고
    • ZD1839, a selective oral epidermal growth factor receptor-tyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: Results of a phase I trial
    • Ranson M, Hammond LA, Ferry D et al: ZD1839, a selective oral epidermal growth factor receptor-tyrosine kinase inhibitor, is well tolerated and active in patients with solid, malignant tumors: results of a phase I trial. J Clin Oncol 20: 2240-2250, 2002.
    • (2002) J Clin Oncol , vol.20 , pp. 2240-2250
    • Ranson, M.1    Hammond, L.A.2    Ferry, D.3
  • 3
    • 0037106377 scopus 로고    scopus 로고
    • Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: Results of a phase I trial
    • Herbst RS, Maddox AM, Rothenberg ML et al: Selective oral epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 is generally well-tolerated and has activity in non-small-cell lung cancer and other solid tumors: results of a phase I trial. J Clin Oncol 20: 3815-3825, 2002.
    • (2002) J Clin Oncol , vol.20 , pp. 3815-3825
    • Herbst, R.S.1    Maddox, A.M.2    Rothenberg, M.L.3
  • 4
    • 0036842170 scopus 로고    scopus 로고
    • Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types
    • Baselga J, Rischin D, Ranson M et al: Phase I safety, pharmacokinetic, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types. J Clin Oncol 20: 4292-4302, 2002.
    • (2002) J Clin Oncol , vol.20 , pp. 4292-4302
    • Baselga, J.1    Rischin, D.2    Ranson, M.3
  • 5
    • 0012381722 scopus 로고    scopus 로고
    • Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer
    • Fukuoka M, Yano S, Giaccone G et al: Multi-institutional randomized phase II trial of gefitinib for previously treated patients with advanced non-small-cell lung cancer. J Clin Oncol 21: 2237-2246, 2003.
    • (2003) J Clin Oncol , vol.21 , pp. 2237-2246
    • Fukuoka, M.1    Yano, S.2    Giaccone, G.3
  • 6
    • 0037673681 scopus 로고    scopus 로고
    • Phase I pharmacokinetic trial of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor gefitinib ("Iressa*, ZD1839) in Japanese patients with solid malignant tumors
    • Nakagawa K, Tamura T, Negoro S et al: Phase I pharmacokinetic trial of the selective oral epidermal growth factor receptor tyrosine kinase inhibitor gefitinib ("Iressa*, ZD1839) in Japanese patients with solid malignant tumors. Ann Oncol 14: 922-930, 2003.
    • (2003) Ann Oncol , vol.14 , pp. 922-930
    • Nakagawa, K.1    Tamura, T.2    Negoro, S.3
  • 7
    • 0142055937 scopus 로고    scopus 로고
    • Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial
    • Kris MG, Natale RB, Herbst RS et al: Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. Jama 290: 2149-2158, 2003.
    • (2003) Jama , vol.290 , pp. 2149-2158
    • Kris, M.G.1    Natale, R.B.2    Herbst, R.S.3
  • 8
    • 0043132288 scopus 로고    scopus 로고
    • Gefitinib in pretreated non-small-cell lung cancer (NSCLC): Analysis of efficacy and correlation with HER2 and epidermal growth factor receptor expression in locally advanced or metastatic NSCLC
    • Cappuzzo F, Gregorc V, Rossi E et al: Gefitinib in pretreated non-small-cell lung cancer (NSCLC): Analysis of efficacy and correlation with HER2 and epidermal growth factor receptor expression in locally advanced or metastatic NSCLC. J Clin Oncol 21: 2658-2663, 2003.
    • (2003) J Clin Oncol , vol.21 , pp. 2658-2663
    • Cappuzzo, F.1    Gregorc, V.2    Rossi, E.3
  • 9
    • 0346057793 scopus 로고    scopus 로고
    • Extensive experience of disease control with gefitinib and the role of prognostic markers
    • Cortes-Funes H and Soto Parra H: Extensive experience of disease control with gefitinib and the role of prognostic markers. Br J Cancer 89 Suppl 2: S3-8, 2003.
    • (2003) Br J Cancer , vol.89 , Issue.SUPPL. 2
    • Cortes-Funes, H.1    Soto Parra, H.2
  • 10
    • 9144244180 scopus 로고    scopus 로고
    • Activity of a specific inhibitor, gefitinib (Iressa, ZD1839), of epidermal growth factor receptor in refractory non-small-cell lung cancer
    • Santoro A, Cavina R, Latteri F et al: Activity of a specific inhibitor, gefitinib (Iressa, ZD1839), of epidermal growth factor receptor in refractory non-small-cell lung cancer. Ann Oncol 15: 33-37, 2004.
    • (2004) Ann Oncol , vol.15 , pp. 33-37
    • Santoro, A.1    Cavina, R.2    Latteri, F.3
  • 11
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch TJ, Bell DW, Sordella R et al: Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350: 2129-2139, 2004.
    • (2004) N Engl J Med , vol.350 , pp. 2129-2139
    • Lynch, T.J.1    Bell, D.W.2    Sordella, R.3
  • 12
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez JG, Janne PA, Lee JC et al: EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304: 1497-1500, 2004.
    • (2004) Science , vol.304 , pp. 1497-1500
    • Paez, J.G.1    Janne, P.A.2    Lee, J.C.3
  • 13
    • 4444344330 scopus 로고    scopus 로고
    • EGF receptor gene mutations are common in lung cancers from "never smokers* and are associated with sensitivity of tumors to gefitinib and erlotinib
    • Pao W, Miller V, Zakowski M et al: EGF receptor gene mutations are common in lung cancers from "never smokers* and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 101: 13306-13311, 2004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 13306-13311
    • Pao, W.1    Miller, V.2    Zakowski, M.3
  • 14
    • 0035476803 scopus 로고    scopus 로고
    • The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells
    • Moasser MM, Basso A, Averbuch SD and Rosen N: The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells. Cancer Res 61: 7184-7188, 2001.
    • (2001) Cancer Res , vol.61 , pp. 7184-7188
    • Moasser, M.M.1    Basso, A.2    Averbuch, S.D.3    Rosen, N.4
  • 15
    • 0037388251 scopus 로고    scopus 로고
    • ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells
    • Anido J, Matar P, Albanell J et al: ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells. Clin Cancer Res 9: 1274-1283, 2003.
    • (2003) Clin Cancer Res , vol.9 , pp. 1274-1283
    • Anido, J.1    Matar, P.2    Albanell, J.3
  • 17
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • Kaplan E and Meier P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53: 457-481, 1985.
    • (1985) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.1    Meier, P.2
  • 18
    • 1842509828 scopus 로고    scopus 로고
    • Bronchioloalveolar pathologic subtype and smoking history predict sensitivity to gefitinib in advanced non-small-cell lung cancer
    • Miller VA, Kris MG, Shah N et al: Bronchioloalveolar pathologic subtype and smoking history predict sensitivity to gefitinib in advanced non-small-cell lung cancer. J Clin Oncol 22: 1103-1109, 2004.
    • (2004) J Clin Oncol , vol.22 , pp. 1103-1109
    • Miller, V.A.1    Kris, M.G.2    Shah, N.3
  • 19
    • 20044364933 scopus 로고    scopus 로고
    • EGFR mutations in non-small-cell lung cancer: Analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment
    • Marchetti A, Martella C, Felicioni L et al: EGFR mutations in non-small-cell lung cancer: analysis of a large series of cases and development of a rapid and sensitive method for diagnostic screening with potential implications on pharmacologic treatment. J Clin Oncol 23: 857-865, 2005.
    • (2005) J Clin Oncol , vol.23 , pp. 857-865
    • Marchetti, A.1    Martella, C.2    Felicioni, L.3
  • 20
    • 0000329007 scopus 로고    scopus 로고
    • A phase II trial of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor OSI-774, following platinum-based chemotherapy, in patients with advanced EGFR-expressing, non-small-cell lung cancer (NSCLC)
    • Perez-Soler R, Chachoua A, Huberman M et al: A phase II trial of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor OSI-774, following platinum-based chemotherapy, in patients with advanced EGFR-expressing, non-small-cell lung cancer (NSCLC). Proc Am Soc Clin Oncol 20: 310a, 2001.
    • (2001) Proc Am Soc Clin Oncol , vol.20
    • Perez-Soler, R.1    Chachoua, A.2    Huberman, M.3
  • 21
    • 0242668485 scopus 로고    scopus 로고
    • Tumor EGFR membrane staining is not clinically relevant for predicting response in patients receiving gefitinib ("Iressa", ZD1839) monotherapy for pretreated advanced non-small cell lung cacner: IDEAL 1 and 2
    • abstract LB-1170
    • Barily L, Kris M, Wolf M et al: Tumor EGFR membrane staining is not clinically relevant for predicting response in patients receiving gefitinib ("Iressa", ZD1839) monotherapy for pretreated advanced non-small cell lung cacner: IDEAL 1 and 2. Proc Am Assoc Cancer Res 44: 1362 (abstract LB-1170), 2004.
    • (2004) Proc Am Assoc Cancer Res , vol.44 , pp. 1362
    • Barily, L.1    Kris, M.2    Wolf, M.3
  • 22
    • 20144377465 scopus 로고    scopus 로고
    • HER2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells
    • Hirata A, Hosoi F, Miyagawa M et al: HER2 overexpression increases sensitivity to gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor, through inhibition of HER2/HER3 heterodimer formation in lung cancer cells. Cancer Res 65: 4253-4260, 2005.
    • (2005) Cancer Res , vol.65 , pp. 4253-4260
    • Hirata, A.1    Hosoi, F.2    Miyagawa, M.3
  • 23
    • 10844231985 scopus 로고    scopus 로고
    • Mutations of the epidermal growth factor receptor gene in lung cancer: Biological and clinical implications
    • Kosaka T, Yatabe Y, Endoh H et al: Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications. Cancer Res 64: 8919-8923, 2004.
    • (2004) Cancer Res , vol.64 , pp. 8919-8923
    • Kosaka, T.1    Yatabe, Y.2    Endoh, H.3
  • 24
    • 20244371965 scopus 로고    scopus 로고
    • EGFR Mutation status in Japanese lung cancer patients: Genotyping analysis using LightCycler
    • Sasaki H, Endo K, Konishi A et al: EGFR Mutation status in Japanese lung cancer patients: genotyping analysis using LightCycler. Clin Cancer Res 11: 2924-2929, 2005.
    • (2005) Clin Cancer Res , vol.11 , pp. 2924-2929
    • Sasaki, H.1    Endo, K.2    Konishi, A.3
  • 25
    • 17844390172 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer: Current knowledge and future directions
    • Pao W and Miller VA: Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer: current knowledge and future directions. J Clin Oncol 23: 2556-2568, 2005.
    • (2005) J Clin Oncol , vol.23 , pp. 2556-2568
    • Pao, W.1    Miller, V.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.