Total synthesis and biological evaluation of viscolin, a 1,3-diphenylpropane as a novel potent anti-inflammatory agent

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 24, 2006, Pages 6155-6160

  Su, Chung Ren ^a   Shen, Yuh Chiang ^b   Kuo, Ping Chung ^a   Leu, Yann Lii ^c   Damu, Amooru G ^a   Wang, Yea Hwey ^d   Wu, Tian Shung ^a,b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^c CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^d NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Cytokine; Free radicals; Leukocyte; Microglial cells; Nitric oxide; Viscolin

Indexed keywords

1,3 DIPHENYLPROPANE; ANTIINFLAMMATORY AGENT; CYTOKINE; HERBACEOUS AGENT; HYDROXYL GROUP; NITRIC OXIDE; QUERCETIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VISCOLIN;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG ACTIVITY; DRUG INDICATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEUKOCYTE; MEDICINAL PLANT; MICROGLIA; MICROWAVE RADIATION; OLEFINATION; OXIDATIVE STRESS; PHARMACOLOGICAL BLOCKING; STRUCTURE ACTIVITY RELATION; VISCUM COLORATUM; WITTIG REACTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BIPHENYL COMPOUNDS; CYTOKINES; HUMANS; LEUKOCYTES; MICE; MICROGLIA; NG-NITROARGININE METHYL ESTER; PROPANE; VISCUM;

VISCUM;

EID: 33750717840     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.09.046     Document Type: Article

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