Synthesis of antioxidative moscatilin and its bibenzyl derivatives

Chinese Pharmaceutical Journal

Volumn 55, Issue 5, 2003, Pages 381-390

  Chen, Chien Chih ^a   Huang, Yu Ling ^a   Shiao, Young Ji ^a   Huang, Ray Ling ^a   Fu, Tai Ti ^a   Shen, Chien Chang ^a  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

Author keywords

Antioxidant; Bibenzyl derivatives; Cytotoxic activity; Moscatilin

Indexed keywords

ALDEHYDES; CYTOLOGY; DERIVATIVES; SALTS; SYNTHESIS (CHEMICAL);

ANTIOXIDATIVE; CYTOTOXIC ACTIVITIES;

DRUG PRODUCTS;

ALDEHYDE DERIVATIVE; ANTIOXIDANT; BIBENZYL DERIVATIVE; MOSCATILIN; PHOSPHONIUM DERIVATIVE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL ASSAY; CHEMICAL REACTION; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MASS SPECTROMETRY; PROTON NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; WITTIG REACTION;

EID: 3142550536     PISSN: 10161015     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Majumder, P. L.; Sen, R. C. Moscatilin, a Bibenzyl Derivative from the Orchid Dendrobium moscatum. Phytochemistry 1987, 26, 2121-2124.
2. Chen, C.-C.; Wu, L.-G.; Ko, F.-N.; Teng, C.-M. Antiplatelet aggregation Principles of Dendrobium loddigesii. J. Nat. Prod. 1994, 57, 1271-1274.
3. Majumder, P. L.; Guha, S.; Sen, S. Bibenzyl Derivatives from the Orchid Dendrobium amoenum. Phytochemistry 1999, 52, 1365-1369.
4. Miyazawa, M.; Shimamura, H.; Nakamura, S.-I.; Sugiura, W.; Kosaka, H.; Kameoka, H. Moscatilin from Dendrobium nobile, a Naturally Occurring Bibenzyl Compound with Potential Antimutagenic Activity. J. Aric. Food Chem. 1999, 47, 2163-2167.
5. Fan, C.; Wang, W.; Wang, Y.; Qin, G.; Zhao, W. Chemical Constituents from Dendrobium densiflorum. Phytochemistry 2001, 57, 1255-1258.
6. Juneja, R. K.; Sharma, S. C.; Tandon, J. S. Two Substituted Bibenzyls and a Dihydrophenanthrene from Cymbidium aloifolium. Phytochemistry 1987, 26, 1123-1125.
7. Majumder, P. L.; Lahiri, S.; Mukhoti, N. Four Stilbenoids from the Orchid Agrostophyllum khasiyanum. Phytochemiostry 1996, 42, 1157-1161.
8. Chen, H.-Y. Screening for Antioxidants from Forsythiae Fructus and Ephemerantha lonchophylla to Inhibit LDL Lipid Peroxidation. Master Thesis: National Yang Ming University, Taipei, Taiwan, 1996.
9. Larrow, J. F.; Jacobsen, E. N.; Gao, Y.; Hong, Y.; Nie, X.; Zepp, C. M. A Practical Method for the Large-Scale Preparation of [N,N′-Bis(3,5-di- tert-butylsalicylidene)-1, 2-cyclohexanediaminato(2-)] manganese(III) Chloride, a Highly Enantioselective Epoxidation Catalyst. J. Org. Chem. 1994, 59, 1939-1942.
10. Pellegrini, N.; Re, R.; Yang, M.; and Rice-Evans, C. Screening of Dietary Carotenoids and Carotenoid-Rich Fruit Extracts for Antioxidant Activities Applying 2,2′-Azinobis(3-ethylenebenzothiazoline-6-sulfonic acid) Radical Cation Decolorization Assay. Meth. Enzymol. 1999, 299, 379-389.
11. Carmichael, J.; DeGraff, W. G.; Gazdar, A. F.; Minna, J. D.; Mitchell, J. B. Evaluation of a Tetrazolium-Based Semiautomated Colorimetric Assay: Assessment of Chemosensitivity Testing. Cancer Res. 1987, 47, 936-942.