Exposure of pregnant rats to uranium and restraint stress: Effects on postnatal development and behavior of the offspring

Toxicology

Volumn 228, Issue 2-3, 2006, Pages 323-332

  Sánchez, Domènec J ^a   Bellés, Montserrat ^a   Albina, Maria L ^a   Gómez, Mercedes ^a   Linares, Victoria ^a   Domingo, José L ^a  

^a UNIVERSITAT ROVIRA I VIRGILI   (Spain)

Author keywords

Behavior; Female rats; Maternal restraint; Oral exposure; Postnatal development; Uranyl acetate dihydrate (UAD)

Indexed keywords

DRINKING WATER; URANIUM; URANYL ACETATE;

ANALYTICAL PARAMETERS; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE LEVEL; BRAIN LEVEL; CELL MATURATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EVALUATION; EXPOSURE; FEMALE; FETUS; FETUS OUTCOME; IMMOBILIZATION STRESS; KIDNEY; LACTATION; MALE; MATING; MAZE TEST; MOTHER; MOTONEURON; NEWBORN; NONHUMAN; OBSERVATION; PASSIVE AVOIDANCE; PHYSICAL DEVELOPMENT; POSTNATAL DEVELOPMENT; PREGNANCY; PRIORITY JOURNAL; PROGENY; RAT;

ANIMALS; AVOIDANCE LEARNING; BEHAVIOR, ANIMAL; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FERTILITY; MALE; MAZE LEARNING; MEMORY; MOTOR ACTIVITY; MUSCULOSKELETAL EQUILIBRIUM; ORGANOMETALLIC COMPOUNDS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; REFLEX; RESTRAINT, PHYSICAL; STRESS, PSYCHOLOGICAL;

EID: 33750714483     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2006.09.017     Document Type: Article

References (39)

1. Abou-Donia M.B., Dechkovskaia A.M., Goldstein L.B., Shah D.U., Bullman S.L., and Kahn W.A. Uranyl-acetate-induced sensorimotor deficit and increased nitric oxide generation in the central nervous system in rats. Pharmacol. Biochem. Behav. 72 (2002) 881-890
2. Abu-Qare A.W., and Abou-Donia M.B. Depleted uranium-the growing concern. J. Appl. Toxicol. 22 (2002) 149-152
3. Albina M.L., Belles M., Gomez M., Sanchez D.J., and Domingo J.L. Influence of maternal stress on uranium-induced developmental toxicity in rats. Exp. Biol. Med. 28 (2003) 1072-1077
4. Albina M.L., Belles M., Linares V., Sanchez D.J., and Domingo J.L. Restraint stress does not enhance the uranium-induced developmental and behavioral effects in the offspring of uranium-exposed male rats. Toxicology 215 (2005) 69-79
5. ATSDR, Agency for Toxic Substances and Disease Registry, 1999. Toxicological profile for uranium. US Department of Health and Human Services, Atlanta, GA. Available at: http://www.atsdr.cdc.gov/tfacts150.html.
6. Bellés M., Albina M.L., Linares V., Gómez M., Sánchez D.J., and Domingo J.L. Combined action of uranium in the rat. I. Behavioral effects. Toxicol. Lett. 158 (2005) 176-185
7. Bleise A., Danesi P.R., and Burkart W. Properties, use and health effects of depleted uranium (DU): a general overview. J. Environ. Radioact. 64 (2003) 93-112
8. Briner W., and Murray J. Effects of short-term and long-term depleted uranium exposure on open-field behaviour and brain lipid oxidation in rats. Neurotoxicol. Teratol. 27 (2005) 135-144
9. Brugge D., de Lemos J.L., and Oldmixon B. Exposure pathways and health effects associated with chemical and radiological toxicity of natural uranium: a review. Rev. Environ. Health 20 (2005) 177-193
10. Bussy C., Lestaevel P., Dhieux B., Amourette C., Paquet F., Gourmelon P., and Houpert P. Chronic ingestion of uranyl nitrate perturbs acetylcholinesterase activity and monoamine metabolism in male rat brain. Neurotoxicology 27 (2006) 245-252
11. Colomina M.T., Albina M.L., Domingo J.L., and Corbella J. Effects of maternal stress on methylmercury-induced developmental toxicity in mice. Physiol. Behav. 58 (1995) 979-984
12. Colomina M.T., Albina M.L., Domingo J.L., and Corbella J. Influence of maternal restraint stress on arsenic-induced pre- and postnatal alterations in mice. Psychobiology 24 (1996) 227-234
13. Colomina M.T., Esparza J.L., Corbella J., and Domingo J.L. The effect of maternal stress on developmental toxicity of aluminum in mice. Neurotoxicol. Teratol. 20 (1998) 651-656
14. Colomina M.T., Sanchez D.J., Domingo J.L., and Sanchez-Turet M. Exposure of pregnant mice to aluminum and restraint stress: Effects on postnatal development and behavior of the offspring. Psychobiology 27 (1999) 521-529
15. Colomina M.T., Roig J.L., Sanchez D.J., and Domingo J.L. Influence of age on aluminum-induced neurobehavioral effects and morphological changes in rat brain. Neurotoxicology 23 (2002) 775-781
16. Colomina M.T., Roig J.L., Torrente M., Vicens P., and Domingo J.L. Concurrent exposure to aluminum and stress during pregnancy in rats: Effects on postnatal development and behavior of the offspring. Neurotoxicol. Teratol. 27 (2005) 565-574
17. Craft E.S., Abu-Qare A.W., Flaherty M.M., Garofolo M.C., Rincavage H.L., and Abou-Donia M.B. Depleted and natural uranium: chemistry and toxicological effects. J. Toxicol. Environ. Health Part B 7 (2004) 297-317
18. Domingo J.L. Chemical toxicity of uranium. Toxicol. Ecotoxicol. News 2 (1995) 74-78
19. Domingo J.L. Reproductive and developmental toxicity of natural and depleted uranium: a review. Reprod. Toxicol. 15 (2001) 603-809
20. Domingo J.L. Adverse effects of aluminum, uranium, and vanadium on reproduction and intrauterine development in mammals. In: Golub M.S. (Ed). Metals, Fertility, and Reproductive Toxicity (2006), CRC Press, Boca Raton, FL 65-91
21. Domingo J.L., Llobet J.M., Tomás J.M., and Corbella J. Acute toxicity of uranium in rats and mice. Bull. Environ. Contam. Toxicol. 39 (1987) 168-174
22. Domingo J.L., Domingo A., and Colomina M.T. Influence of maternal stress on metal-induced pre- and postnatal effects in mammals: a review. Biol. Trace Elem. Res. 98 (2004) 193-207
23. Golub M.S., Campbell M.A., Kaufman F.L., Iyer P., Li H.L., Donald J.M., and Morgan J.E. Effects of restraint stress in gestation: implications for rodent developmental toxicology studies. Birth Defects Res. B. Dev. Reprod. Toxicol. 71 (2004) 26-36
24. Lemercier V., Millot X., Ansoborlo E., Ménétrier F., Flüry-Hérard A., Rousselle Ch., and Scherrmann J.M. Study of uranium transfer across the blood-brain barrier. Radiat. Prot. Dosimetry 105 (2003) 243-245
25. Linares V., Bellés M., Albina M.L., Mayayo E., Sánchez D.J., and Domingo J.L. Combined action of uranium and stress in the rat. II. Effects on male reproduction. Toxicol. Lett. 158 (2005) 186-195
26. Llobet J.M., Sirvent J.J., Ortega A., and Domingo J.L. Influence of chronic exposure to uranium on male reproduction in mice. Fundam. Appl. Toxicol. 16 (1991) 821-829
27. Monleau M., Bussy C., Lestaevel P., Houpert P., Paquet F., and Chazel V. Bioaccumulation and behavioral effects of depleted uranium in rats exposed to repeated inhalations. Neurosci. Lett. 390 (2005) 31-36
28. Morris R. Developments of water-maze procedure for studying spatial learning in the rat. J. Neurosci. Meth. 11 (1984) 47-60
29. Nagahara A.H., Otto T., and Gallagher M. Entorhinal-perirhinal lesions impair performance of rats on two versions of place learning in the Morris water maze. Behav. Neurosci. 109 (1995) 3-9
30. Ozmen M., and Yurekli M. Subacute toxicity of uranyl acetate in Swiss-Albino mice. Environ. Toxicol. Pharmacol. 6 (1998) 111-115
31. Paquet F., Houpert P., Blanchardon E., Delissen O., Maubert C., Dhieux B., Moreels A.M., Frelon S., and Gourmelon P. Accumulation and distribution of uranium in rats after chronic exposure by ingestion. Health Phys. 90 (2006) 139-147
32. Paternain J.L., Domingo J.L., Ortega A., and Llobet J.M. The effects of uranium on reproduction, gestation and postnatal survival in mice. Ecotoxicol. Environ. Safety 17 (1989) 291-296
33. Souidi M., Gueguen Y., Linard C., Dudoignon N., Grison S., Baudelin C., Marquette C., Gourmelon P., Aigueperse J., and Dublineau I. In vivo effects of chronic contamination with depleted uranium on CYP3A and associated nuclear receptors PXR and CAR in the rat. Toxicology 214 (2005) 113-122
34. Tannenbaum A. Toxicology of Uranium (1951), McGraw-Hill, New York
35. Taylor D.M., and Taylor S.K. Environmental uranium and human health. Rev. Environ. Health 12 (1997) 147-157
36. Torrente M., Colomina M.T., and Domingo J.L. Effects of prenatal exposure to manganese on postnatal development and behavior in mice: Influence of maternal restraint. Neurotoxicol. Teratol. 24 (2002) 219-225
37. Torrente M., Colomina M.T., and Domingo J.L. Behavioral effects of adult rats concurrently exposed to high doses of oral manganese and restraint stress. Toxicology 211 (2005) 59-69
38. US EPA, 2002. Facts about uranium. Available at: http://www.epa.gov/superfund/resources/radiation/pdf/uranium.pdf.
39. Voetglin C., and Hodge H.C. The Pharmacology and Toxicology of Uranium Compounds (1953), McGraw-Hill, New York