Combined effects of atorvastatin and soybean isoflavones on hypercholesterolemia and lipoprotein metabolism

Chinese Journal of Pharmacology and Toxicology

Volumn 20, Issue 5, 2006, Pages 381-386

  He, Xu Dong ^a   Wu, Hong Hai ^a   Lou, Yi Jia ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Atorvastatin; Lipoproteins; Metabolism; Soybean isoflavones

Indexed keywords

APOLIPOPROTEIN A1; ATORVASTATIN; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; ISOFLAVONE DERIVATIVE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; OIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG INHIBITION; ENZYMATIC ASSAY; FROZEN SECTION; HYPERCHOLESTEROLEMIA; LIPID DIET; LIPOPROTEIN METABOLISM; LIVER CELL; NONHUMAN; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOYBEAN; STAINING; WESTERN BLOTTING;

GLYCINE MAX;

EID: 33750684949     PISSN: 10003002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Endo A. The discovery and development of HMG-CoA reductase inhibitors[J]. Lipid Res, 2003, 33(4):1569-1582.
2. Artaud-Wild SM, Connor SL, Sexton G. Differences in coronary mortality can be explained differences in cholesterol and saturated fat intakes in 40 countries but not in France and Finland[J]. Circulation, 1993, 99(5): 2771-2779.
3. Lovati MR, Manzoni C, Canavesi A. Soybean protein diet increases low density lipoprotein receptor activity in mononuclear cells from hypercholesterol patients[J]. Clin Invest, 1987, 80(7):1498-1502.
4. Potter SM, Baum JA, Teng H. Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women[J]. Am J Clin Nutr, 1998, 68 (1):1375-1379.
5. Williams KJ, Fless GM. Mechanism by which lipoprotein lipase alters cellular metabolism of lipoprotein(a), low density lipoprotein and nascent lipoproteins[J]. J Biol Chem, 1992, 267(19):13284-13292.
6. 1 genes in the rat[J]. Biochem Biophys Res, 1994, 27(3):1510-1517.
7. Bradford MM. A rapid and sensitive method for the quantification of microgram quantificaties of protein utilizing the principle of protein dye binding[J]. Anal Biochem, 1976, 72(1):248-254.
8. Brown AS, Bakker-Arkema RG. Treating patients with documented atherosclerosis to National Cholesterol Education Program-recommended low-density-lipoprotein cholesterol goals with atorvastatin, fluvastatin, lovastatin and simvastatin[J]. Am Coll Cardiol, 1998, 32(3): 665-672.
9. Kashyap ML, Evans R, Simmons PD. New combination niacin/statin formulation shows pronounced effects on major lipoproteins and is well tolerated [abstract][J]. Am Coll Cardiol, 2000, 35(Suppl A):326A.
10. Yamakoshi J, Piskula MK, Izumi T. Isoflavone, a glycone rich extract without soy protein attenuates atherosclerosis development in cholesterol-fed rabbits[J]. J Nutr, 2000, 130(1):1887-1893.
11. Stein EA. New statins and new doses of older statins [J]. Curr Atherosler Rep, 2000, 11(3):14-28.
12. 1 gene expression by posttranscriptional mechanism[J]. Biochem Mol Biol Int, 1994, 34(5):393-402.