Papaya glutamine cyclotransferase shows a singular five-fold β-propeller architecture that suggests a novel reaction mechanism

Biological Chemistry

Volumn 387, Issue 10-11, 2006, Pages 1479-1486

  Guevara, Tibisay ^a,b   Mallorquí Fernández, Noemí ^a,b   García Castellanos, Raquel ^a,b   García Piqué, Sonia ^a,b   Petersen, Gitte Ebert ^c   Lauritzen, Conni ^c   Pedersen, John ^c   Arnau, José ^c   Gomis Rüth, F Xavier ^a,b   Solà, Maria ^a,b  

^a INSTITUT DE BIOLOGIA MOLECULAR DE BARCELONA   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c Unizyme Laboratories A/S   (Denmark)

Author keywords

Baculovirus expression system; Carica papaya plant glutaminyl cyclase; Insect cell culture; N terminal cyclisation; Pyroglutamate; Recombinant glutaminyl cyclase; X ray crystal structure

Indexed keywords

GLUTAMINYL CYCLOTRANSFERASE; RECOMBINANT ENZYME; UNCLASSIFIED DRUG;

ACID BASE BALANCE; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; BETA SHEET; CONFERENCE PAPER; CYCLIZATION; ENZYME ACTIVE SITE; ENZYME DEGRADATION; ENZYME DENATURATION; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; MOLECULAR INTERACTION; PAPAYA; PRIORITY JOURNAL; STRUCTURAL PROTEOMICS;

CARICA PAPAYA; INSECTA; MAMMALIA;

EID: 33750629800     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/BC.2006.185     Document Type: Conference Paper

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