Short-term low-dose propofol anaesthesia associated with severe metabolic acidosis

Anaesthesia and Intensive Care

Volumn 34, Issue 5, 2006, Pages 651-655

  Chukwuemeka, A ^a,c   Ko, R ^b   Ralph Edwards, A ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c KING S COLLEGE HOSPITAL   (United Kingdom)

Author keywords

Acidosis; Anaesthesia; Propofol

Indexed keywords

ACETYLSALICYLIC ACID; ADRENALIN; AMIODARONE; DIPHENHYDRAMINE; DOPAMINE; FENTANYL; HEPARIN; HYDROCORTISONE; METOPROLOL; MIDAZOLAM; PANCURONIUM; PROPOFOL; PROTAMINE; ROCURONIUM;

ADULT; ANAPHYLACTIC SHOCK; ARTICLE; CASE REPORT; CORONARY ARTERY BYPASS GRAFT; CORONARY ARTERY OBSTRUCTION; DRUG WITHDRAWAL; GENERAL ANESTHESIA; HUMAN; INTENSIVE CARE; LACTIC ACIDOSIS; LOW DRUG DOSE; MALE; METABOLIC ACIDOSIS; RESUSCITATION; SEDATION;

EID: 33750627150     PISSN: 0310057X     EISSN: None     Source Type: Journal    
DOI: 10.1177/0310057x0603400503     Document Type: Article

References (18)

1. Glen JB, Hunter SC. Pharmacology of an emulsion formulation of ICI 35.868. Br J Anaesth 1984; 56:617-626.
2. Markowitz BP. Rare events often happen infrequently: propofol complications revisited. Crit Care Med 2000; 28:1367-1368.
3. Bray RJ. Propofol infusion in children. Paediatr Anaesth 1998; 8:491-499.
4. Hanna JP, Ramundo ML. Rhabdomyolysis and hypoida associated with prolonged propofol infusion in children. Neurology 1998; 50:301-303.
5. Perrier ND, Baerga-Varela Y, Murray MJ. Death related to propofol use in an adult patient. Crit Care Med 2000; 28:3071-3074.
6. Ernest D, French C. Propofol infusion syndrome - report of an adult fatality. Anaesth Intensive Care 2003; 31:316-319.
7. Brussel T, Thiessen JL, Vigfusson G et al. Haemodynamic and cardiodynamic effects of propofol and etomidate: negative inotropic properties of propofol. Anesth Anaig 1989; 69:35-40.
8. Burow BK, Johnson ME, Packer DL. Metabolic acidosis associated with propofol in the absence of other causative factors. Anesthesiology 2004; 101:239-241.
9. Bennett SN, McNeil MM, Bland LA et al. Postoperative infections traced to contamination of an intravenous anesthetic, propofol. N Engl J Med 1995; 333:147-154.
10. Prough DS, White RT. Acidosis associated with perioperative saline administration: dilution or delusion? Anesthesiology 2000; 93:1167-1169.
11. Vasile B, Rasulo F, Candiani A, Lantrico N. The pathophysiology of propofol infusion syndrome: a simple name for a complex syndrome. Intensive Care Med 2003; 29:1417-1425.
12. Kelly Df. Propofol infusion syndrome. J Neurosurg 2001; 95:925-926.
13. Wolf A, Weir P, Segar P, Stone J, Shield J. Impaired fatty acid oxidation in propofol infusion syndrome. Lancet 2001; 357:606-607.
14. Cray SH, Robinson BH, Cox PN. Lactic acidaemia and bradyarrythmia in a child sedated with propofol. Crit Care Med 1998; 26:2087-2092.
15. Mehta N, DeMunter C, Habibi P, Nadel S, Britto J. Short-term propofol infusions in children. Lancet 1999; 354:866-867.
16. Schenkman KA, Yan S. Propofol impairment of mitochondrial respiration in isolated perfused guinea pig hearts determined by reflectance spectroscopy. Crit Care Med 2000; 28:172-177.
17. Cohen BH, Gold DR. Mitochondrial cytopathy in adults: what we know so far. Cleveland Clinic J Med 2001; 68:629-642.
18. Munoz R, Goldberg ME, Cantillo J et al. Perioperative arrhythmias with a propofol-based anesthetic. J Clin Anesth 1991; 3:149-152.